3OB4

MBP-fusion protein of the major peanut allergen Ara h 2

Summary for 3OB4

Entry DOI	10.2210/pdb3ob4/pdb
Related PRD ID	PRD_900009
Descriptor	Maltose ABC transporter periplasmic protein,Arah 2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, SULFATE ION, ... (5 entities in total)
Functional Keywords	alpha-amylase inhibitors (aai), lipid transfer (lt) and seed storage (ss) protein family, seed storage protein, allergen, fusion protein, chimera protein
Biological source	Escherichia coli More
Total number of polymer chains	1
Total formula weight	56628.31
Authors	Mueller, G.A.,Gosavi, R.A.,Moon, A.F.,London, R.E.,Pedersen, L.C. (deposition date: 2010-08-06, release date: 2011-02-02, Last modification date: 2024-10-09)
Primary citation	Mueller, G.A.,Gosavi, R.A.,Pomes, A.,Wunschmann, S.,Moon, A.F.,London, R.E.,Pedersen, L.C. Ara h 2: crystal structure and IgE binding distinguish two subpopulations of peanut allergic patients by epitope diversity. Allergy, 66:878-885, 2011 Cited by PubMed Abstract: Peanut allergy affects 1% of the population and causes the most fatal food-related anaphylactic reactions. The protein Ara h 2 is the most potent peanut allergen recognized by 80-90% of peanut allergic patients. PubMed: 21255036 DOI: 10.1111/j.1398-9995.2010.02532.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.706 Å)

Structure validation