1R6Z

The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion)

Summary for 1R6Z

Entry DOI	10.2210/pdb1r6z/pdb
Related PRD ID	PRD_900001
Descriptor	Chimera of Maltose-binding periplasmic protein and Argonaute 2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, NICKEL (II) ION, ... (4 entities in total)
Functional Keywords	deviant ob fold, rnai, gene regulation
Biological source	Escherichia coli (, fruit fly) More
Total number of polymer chains	3
Total formula weight	170956.09
Authors	Song, J.J.,Liu, J.,Tolia, N.H.,Schneiderman, J.,Smith, S.K.,Martienssen, R.A.,Hannon, G.J.,Joshua-Tor, L. (deposition date: 2003-10-17, release date: 2004-01-13, Last modification date: 2023-08-23)
Primary citation	Song, J.J.,Liu, J.,Tolia, N.H.,Schneiderman, J.,Smith, S.K.,Martienssen, R.A.,Hannon, G.J.,Joshua-Tor, L. The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat.Struct.Biol., 10:1026-1032, 2003 Cited by PubMed: 14625589 DOI: 10.1038/nsb1016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation