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6R1I
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BU of 6r1i by Molmil
Structure of porcine Aichi virus polymerase
Descriptor: Genome polyprotein
Authors:Dubankova, A, Boura, E.
Deposit date:2019-03-14
Release date:2019-10-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.634 Å)
Cite:Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation.
J.Struct.Biol., 208, 2019
5XE0
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BU of 5xe0 by Molmil
Crystal structure of EV-D68-3Dpol in complex with GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein
Authors:Xie, W, Wang, C, Wang, Z, Li, Q, Wang, C.
Deposit date:2017-03-30
Release date:2017-06-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure and Thermostability Characterization of Enterovirus D68 3Dpol
J. Virol., 91, 2017
5JXS
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BU of 5jxs by Molmil
Mutant GC216/7AA of 3D polymerase from Foot-and-Mouth Disease Virus
Descriptor: MAGNESIUM ION, RNA Primer, RNA Template, ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2016-05-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication.
J.Virol., 90, 2016
5TSN
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BU of 5tsn by Molmil
Crystal structures of Norwalk virus polymerase bound to an RNA primer-template duplex
Descriptor: MANGANESE (II) ION, Norwalk virus polymerase, RNA (5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3')
Authors:Shaik, M.M, Ng, K.K.
Deposit date:2016-10-30
Release date:2017-04-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Norovirus RNA-dependent RNA polymerase: A computational study of metal-binding preferences.
Proteins, 85, 2017
1WNE
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BU of 1wne by Molmil
Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with a template-primer RNA
Descriptor: 5'-R(*CP*AP*UP*GP*GP*GP*CP*C)-3', 5'-R(*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ...
Authors:Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
Deposit date:2004-07-31
Release date:2004-08-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA
J.Biol.Chem., 279, 2004
6S2L
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BU of 6s2l by Molmil
FMDV 3D polymerase crystallized in presence of (F)uridylylated VPg peptide
Descriptor: GLYCEROL, Genome polyprotein
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2019-06-21
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:(F)uridylylated Peptides Linked to VPg1 of Foot-and- Mouth Disease Virus (FMDV): Design, Synthesis and X-Ray Crystallography of the Complexes with FMDV RNA-Dependent RNA Polymerase.
Molecules, 24, 2019
3DDK
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BU of 3ddk by Molmil
Coxsackievirus B3 3Dpol RNA Dependent RNA Polymerase
Descriptor: RNA polymerase B3 3Dpol, SODIUM ION, SULFATE ION
Authors:Campagnola, G, Weygandt, M.H, Scoggin, K.E, Peersen, O.B.
Deposit date:2008-06-05
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of Coxsackievirus B3 3Dpol Highlights Functional Importance of Residue 5 in Picornaviral Polymerases
J.Virol., 82, 2008
4B02
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BU of 4b02 by Molmil
The C-terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage phi6 RNA-Dependent RNA Polymerase
Descriptor: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
Authors:Sarin, L.P, Wright, S, Chen, Q, Degerth, L.H, Stuart, D.I, Grimes, J.M, Bamford, D.H, Poranen, M.M.
Deposit date:2012-06-27
Release date:2012-08-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The C-Terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage Phi6 RNA-Dependent RNA Polymerase.
Virology, 432, 2012
6QWT
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BU of 6qwt by Molmil
Sicinivirus 3Dpol RNA dependent RNA polymerase
Descriptor: Genome polyprotein
Authors:Dubankova, A, Boura, E.
Deposit date:2019-03-06
Release date:2019-10-09
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation.
J.Struct.Biol., 208, 2019
4IKA
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BU of 4ika by Molmil
Crystal structure of EV71 3Dpol-VPg
Descriptor: 3Dpol, NICKEL (II) ION, VPg
Authors:Chen, C, Wang, Y.X, Lou, Z.Y.
Deposit date:2012-12-25
Release date:2013-09-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: implication for a trans mechanism of VPg uridylylation
J.Virol., 87, 2013
7W9S
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BU of 7w9s by Molmil
Crystal structure of the enterovirus 71 polymerase elongation complex (C1S3 form)
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Genome polyprotein, MAGNESIUM ION, ...
Authors:Wang, M, Gong, P.
Deposit date:2021-12-10
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Crystal structure of a pre-chemistry viral RNA-dependent RNA polymerase suggests participation of two basic residues in catalysis.
Nucleic Acids Res., 50, 2022
5F8J
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BU of 5f8j by Molmil
Enterovirus 71 Polymerase Elongation Complex (C1S4 Form)
Descriptor: GLYCEROL, Genome polyprotein, MAGNESIUM ION, ...
Authors:Shu, B, Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.675 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
3CDU
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BU of 3cdu by Molmil
Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with a pyrophosphate
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B.
Deposit date:2008-02-27
Release date:2008-07-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
J.Virol., 82, 2008
3CDW
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BU of 3cdw by Molmil
Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with protein primer VPg and a pyrophosphate
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B.
Deposit date:2008-02-27
Release date:2008-07-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
J.Virol., 82, 2008
8C2P
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BU of 8c2p by Molmil
FMDV 3D polymerase in complex with 3B3
Descriptor: Protein 3B-3, RNA-directed RNA polymerase 3D-POL
Authors:Ferrer-Orta, C, Veraguer, N.
Deposit date:2022-12-22
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes.
Plos Pathog., 19, 2023
8C1N
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BU of 8c1n by Molmil
FMDV 3D polymerase in complex with 3B1 protein solved in P212121 space group
Descriptor: ACETATE ION, GLYCEROL, Protein 3B-1, ...
Authors:Ferrer-Orta, C, Veraguer, N.
Deposit date:2022-12-20
Release date:2023-04-26
Last modified:2023-05-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes.
Plos Pathog., 19, 2023
3H5Y
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BU of 3h5y by Molmil
Norovirus polymerase+primer/template+CTP complex at 6 mM MnCl2
Descriptor: 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', CYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S.
Deposit date:2009-04-22
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site.
J.Mol.Biol., 390, 2009
8IIB
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BU of 8iib by Molmil
Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta85 mutant (residues 86-546)
Descriptor: CADMIUM ION, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Fang, X, Lu, G, Hou, C, Gong, P.
Deposit date:2023-02-24
Release date:2023-06-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding.
Virol Sin, 38, 2023
8IIC
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BU of 8iic by Molmil
Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta40 mutant (residues 41-546)
Descriptor: Polymerase polyprotein
Authors:Fang, X, Lu, G, Hou, C, Gong, P.
Deposit date:2023-02-24
Release date:2023-06-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding.
Virol Sin, 38, 2023
5N8X
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BU of 5n8x by Molmil
Trigonal structure of mutant V173I of 3D polymerase from Foot-and-Mouth Disease Virus
Descriptor: 3D polymerase, GLYCEROL, MANGANESE (II) ION
Authors:Ferrer-Orta, C, Verdaguer, N.
Deposit date:2017-02-24
Release date:2017-05-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.
Genome Biol Evol, 9, 2017
5N95
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BU of 5n95 by Molmil
Tetragonal structure of mutant V173I of 3D polymerase from Foot-and-Mouth Disease Virus
Descriptor: 3D polymerase, TRIPHOSPHATE
Authors:Ferrer-Orta, C, Verdaguer, N.
Deposit date:2017-02-24
Release date:2017-05-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.
Genome Biol Evol, 9, 2017
6GVV
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BU of 6gvv by Molmil
Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus
Descriptor: GLYCEROL, RNA polymerase 3D
Authors:Verdaguer, N, Ferrer Orta, C.
Deposit date:2018-06-21
Release date:2018-08-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.
J.Virol., 92, 2018
6GVY
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BU of 6gvy by Molmil
Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with an template -primer RNA
Descriptor: GLYCEROL, Genome polyprotein, RNA (5'-R(P*CP*CP*GP*GP*G)-3'), ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2018-06-21
Release date:2018-08-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.
J. Virol., 92, 2018
3H5X
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BU of 3h5x by Molmil
Crystal Structure of 2'-amino-2'-deoxy-cytidine-5'-triphosphate bound to Norovirus GII RNA polymerase
Descriptor: 2'-amino-2'-deoxycytidine 5'-(tetrahydrogen triphosphate), 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', ...
Authors:Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S.
Deposit date:2009-04-22
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site.
J.Mol.Biol., 390, 2009
1RA7
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BU of 1ra7 by Molmil
Poliovirus Polymerase with GTP
Descriptor: ACETIC ACID, GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2003-10-31
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004

221051

數據於2024-06-12公開中

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