8VLI
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![BU of 8vli by Molmil](/molmil-images/mine/8vli) | Cryo-EM structure of human HGSNAT bound with CoA and product analog | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-methyl-2-oxo-2H-1-benzopyran-7-yl 2-acetamido-2-deoxy-beta-D-glucopyranoside, ... | Authors: | Li, F, Zhao, B. | Deposit date: | 2024-01-11 | Release date: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome To Be Published
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8VEL
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![BU of 8vel by Molmil](/molmil-images/mine/8vel) | IsPETase - ACCCC mutant | Descriptor: | Poly(ethylene terephthalate) hydrolase, SULFATE ION | Authors: | Joho, Y, Royan, S, Newton, S, Caputo, A.T, Ardevol Grau, A, Jackson, C. | Deposit date: | 2023-12-19 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.624 Å) | Cite: | Enhancing PET Degrading Enzymes: A Combinatory Approach. Chembiochem, 25, 2024
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1IAR
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![BU of 1iar by Molmil](/molmil-images/mine/1iar) | INTERLEUKIN-4 / RECEPTOR ALPHA CHAIN COMPLEX | Descriptor: | PROTEIN (INTERLEUKIN-4 RECEPTOR ALPHA CHAIN), PROTEIN (INTERLEUKIN-4) | Authors: | Hage, T, Sebald, W, Reinemer, P. | Deposit date: | 1999-02-25 | Release date: | 2000-03-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface. Cell(Cambridge,Mass.), 97, 1999
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1IAZ
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![BU of 1iaz by Molmil](/molmil-images/mine/1iaz) | EQUINATOXIN II | Descriptor: | EQUINATOXIN II, SULFATE ION | Authors: | Athanasiadis, A, Anderluh, G, Macek, P, Turk, D. | Deposit date: | 2001-03-24 | Release date: | 2001-04-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the soluble form of equinatoxin II, a pore-forming toxin from the sea anemone Actinia equina. Structure, 9, 2001
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8W50
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![BU of 8w50 by Molmil](/molmil-images/mine/8w50) | |
1I83
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![BU of 1i83 by Molmil](/molmil-images/mine/1i83) | BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH N1,N14-BIS((S-METHYL)ISOTHIOUREIDO)TETRADECANE (H4B FREE) | Descriptor: | ACETATE ION, GLYCEROL, N1,N14-BIS((S-METHYL)ISOTHIOUREIDO)TETRADECANE, ... | Authors: | Raman, C.S, Li, H, Martasek, P, Babu, B.R, Griffith, O.W, Masters, B.S.S, Poulos, T.L. | Deposit date: | 2001-03-12 | Release date: | 2001-08-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase. J.Biol.Chem., 276, 2001
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8U4T
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![BU of 8u4t by Molmil](/molmil-images/mine/8u4t) | |
8TQM
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![BU of 8tqm by Molmil](/molmil-images/mine/8tqm) | |
8UI0
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![BU of 8ui0 by Molmil](/molmil-images/mine/8ui0) | |
8UBZ
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![BU of 8ubz by Molmil](/molmil-images/mine/8ubz) | Choline-bound FLVCR1 | Descriptor: | CHOLESTEROL HEMISUCCINATE, CHOLINE ION, Heme transporter FLVCR1 | Authors: | Hite, R.K, Son, Y. | Deposit date: | 2023-09-25 | Release date: | 2024-03-27 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1. Nature, 629, 2024
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8UFP
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![BU of 8ufp by Molmil](/molmil-images/mine/8ufp) | Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine dihydrochloride | Descriptor: | (7M)-4-methyl-7-(4-methyl-2,3,4,5-tetrahydro-1,4-benzoxazepin-7-yl)quinolin-2-amine, GLYCEROL, Nitric oxide synthase, ... | Authors: | Li, H, Poulos, T.L. | Deposit date: | 2023-10-04 | Release date: | 2024-03-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic and Computational Insights into Isoform-Selective Dynamics in Nitric Oxide Synthase. Biochemistry, 63, 2024
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8UFR
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![BU of 8ufr by Molmil](/molmil-images/mine/8ufr) | Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine dihydrochloride | Descriptor: | (7M)-4-methyl-7-(4-methyl-2,3,4,5-tetrahydro-1,4-benzoxazepin-7-yl)quinolin-2-amine, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, ... | Authors: | Li, H, Poulos, T.L. | Deposit date: | 2023-10-04 | Release date: | 2024-03-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.871 Å) | Cite: | Crystallographic and Computational Insights into Isoform-Selective Dynamics in Nitric Oxide Synthase. Biochemistry, 63, 2024
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8UHD
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![BU of 8uhd by Molmil](/molmil-images/mine/8uhd) | Structure of paused transcription complex Pol II-DSIF-NELF - post-translocated | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... | Authors: | Su, B.G, Vos, S.M. | Deposit date: | 2023-10-08 | Release date: | 2024-03-20 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 84, 2024
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1I5H
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8UBX
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![BU of 8ubx by Molmil](/molmil-images/mine/8ubx) | Ethanolamine-bound FLVCR1 | Descriptor: | CHOLESTEROL HEMISUCCINATE, ETHANOLAMINE, Heme transporter FLVCR1 | Authors: | Hite, R.K, Son, Y. | Deposit date: | 2023-09-25 | Release date: | 2024-03-27 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1. Nature, 629, 2024
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8TRM
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![BU of 8trm by Molmil](/molmil-images/mine/8trm) | Actin 1 from T. gondii in filaments bound to MgADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, MAGNESIUM ION | Authors: | Hvorecny, K.L, Sladewski, T.E, Heaslip, A.T, Kollman, J.M. | Deposit date: | 2023-08-09 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Toxoplasma gondii actin filaments are tuned for rapid disassembly and turnover. Nat Commun, 15, 2024
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8UHG
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![BU of 8uhg by Molmil](/molmil-images/mine/8uhg) | |
1I8Z
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![BU of 1i8z by Molmil](/molmil-images/mine/1i8z) | CARBONIC ANHYDRASE II COMPLEXED WITH AL-6629 2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE, 2-(3-METHOXYPHENYL)-3-(4-MORPHOLINYL)-, 1,1-DIOXIDE | Descriptor: | 6-[N-(3-METHOXY-PHENYL)-3-(MORPHOLIN-4-YLMETHYL)-2H-THIENO[3,2-E]-1,2-THIAZINE-1,1,-DIOXIDE]-SULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... | Authors: | Kim, C.-Y, Chang, J.S, Liao, J, May, J.A, Christianson, D.W. | Deposit date: | 2001-03-16 | Release date: | 2001-03-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structural aspects of isozyme selectivity in the binding of inhibitors to carbonic anhydrases II and IV. J.Med.Chem., 45, 2002
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8UQP
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![BU of 8uqp by Molmil](/molmil-images/mine/8uqp) | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Ebright, R.H. | Deposit date: | 2023-10-24 | Release date: | 2024-05-29 | Last modified: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of RfaH-mediated transcription-translation coupling. Nat.Struct.Mol.Biol., 2024
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8TTG
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![BU of 8ttg by Molmil](/molmil-images/mine/8ttg) | NorA single mutant - E222Q at pH 7.5 | Descriptor: | FabDA1 CDRH3 loop, Quinolone resistance protein NorA | Authors: | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | Deposit date: | 2023-08-13 | Release date: | 2024-05-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Proton-coupled transport mechanism of the efflux pump NorA. Nat Commun, 15, 2024
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1I9Q
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![BU of 1i9q by Molmil](/molmil-images/mine/1i9q) | CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4-(AMINOSULFONYL)-N-[(3,4,5-TRIFLUOROPHENYL)METHYL]-BENZAMIDE | Descriptor: | 4-(AMINOSULFONYL)-N-[(3,4,5-TRIFLUOROPHENYL)METHYL]-BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... | Authors: | Kim, C.-Y, Chandra, P.P, Jain, A, Christianson, D.W. | Deposit date: | 2001-03-20 | Release date: | 2001-03-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Fluoroaromatic-fluoroaromatic interactions between inhibitors bound in the crystal lattice of human carbonic anhydrase II. J.Am.Chem.Soc., 123, 2001
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8U3F
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1I90
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![BU of 1i90 by Molmil](/molmil-images/mine/1i90) | CARBONIC ANHYDRASE II COMPLEXED WITH AL-8520 2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE, 4-AMINO-3,4-DIHYDRO-2-(3-METHOXYPROPYL)-, 1,1-DIOXIDE, (R) | Descriptor: | 4-AMINO-6-[N-(3-METHOXYLPROPYL)-2H-THIENO[3,2-E][1,2]THIAZINE 1,1-DIOXIDE]-SULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... | Authors: | Kim, C.-Y, Chang, J.S, Liao, J, May, J.A, Christianson, D.W. | Deposit date: | 2001-03-16 | Release date: | 2001-03-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural aspects of isozyme selectivity in the binding of inhibitors to carbonic anhydrases II and IV. J.Med.Chem., 45, 2002
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8U3D
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8U53
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![BU of 8u53 by Molmil](/molmil-images/mine/8u53) | Mechanically activated ion channel OSCA3.1 in nanodiscs | Descriptor: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CSC1-like protein ERD4, PALMITIC ACID, ... | Authors: | Jojoa-Cruz, S, Lee, W.H, Ward, A.B. | Deposit date: | 2023-09-12 | Release date: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structure-guided mutagenesis of OSCAs reveals differential activation to mechanical stimuli. Elife, 12, 2024
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