8W50
Crystal structure of DNA binding and cleavage core of human topoisomerase 2-alpha in a DNA binding-competent conformation
Summary for 8W50
Entry DOI | 10.2210/pdb8w50/pdb |
Descriptor | DNA topoisomerase 2-alpha, SULFATE ION (3 entities in total) |
Functional Keywords | eukaryotic dna topoisomerase g-segment dna binding cleavage center assembly, dna binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 371959.19 |
Authors | |
Primary citation | Chan, N.L.,Liu, K.T.,Chen, S.F. Structural Basis for the Assembly of Type IIA Topoisomerase DNA Cleavage/Religation Center To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.67 Å) |
Structure validation
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