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1I8Z

CARBONIC ANHYDRASE II COMPLEXED WITH AL-6629 2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE, 2-(3-METHOXYPHENYL)-3-(4-MORPHOLINYL)-, 1,1-DIOXIDE

Summary for 1I8Z
Entry DOI10.2210/pdb1i8z/pdb
Related1I90 1I91
DescriptorCARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (5 entities in total)
Functional Keywordscarbonic anhydrase ii, al-6629, lyase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm : P00918
Total number of polymer chains1
Total formula weight29895.43
Authors
Kim, C.-Y.,Chang, J.S.,Liao, J.,May, J.A.,Christianson, D.W. (deposition date: 2001-03-16, release date: 2001-03-28, Last modification date: 2024-02-07)
Primary citationKim, C.Y.,Whittington, D.A.,Chang, J.S.,Liao, J.,May, J.A.,Christianson, D.W.
Structural aspects of isozyme selectivity in the binding of inhibitors to carbonic anhydrases II and IV.
J.Med.Chem., 45:888-893, 2002
Cited by
PubMed: 11831900
DOI: 10.1021/jm010163d
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.93 Å)
Structure validation

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