1I83

BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH N1,N14-BIS((S-METHYL)ISOTHIOUREIDO)TETRADECANE (H4B FREE)

Summary for 1I83

Entry DOI	10.2210/pdb1i83/pdb
Related	1D1X 1D1Y
Descriptor	NITRIC OXIDE SYNTHASE, ACETATE ION, ZINC ION, ... (7 entities in total)
Functional Keywords	alpha-beta fold, oxidoreductase
Biological source	Bos taurus (cattle)
Cellular location	Cell membrane: P29473
Total number of polymer chains	2
Total formula weight	102129.28
Authors	Raman, C.S.,Li, H.,Martasek, P.,Babu, B.R.,Griffith, O.W.,Masters, B.S.S.,Poulos, T.L. (deposition date: 2001-03-12, release date: 2001-08-08, Last modification date: 2011-07-13)
Primary citation	Raman, C.S.,Li, H.,Martasek, P.,Babu, B.R.,Griffith, O.W.,Masters, B.S.,Poulos, T.L. Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase. J.Biol.Chem., 276:26486-26491, 2001 Cited by PubMed: 11331290 DOI: 10.1074/jbc.M102255200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation