1IAZ

EQUINATOXIN II

Summary for 1IAZ

• Entry DOI: 10.2210/pdb1iaz/pdb
• Descriptor: EQUINATOXIN II, SULFATE ION (3 entities in total)
• Functional Keywords: beta-sandwich, toxin
• Biological source: Actinia equina
• Total number of polymer chains: 2
• Total formula weight: 40747.55

Authors

Athanasiadis, A.,Anderluh, G.,Macek, P.,Turk, D. (deposition date: 2001-03-24, release date: 2001-04-04, Last modification date: 2024-02-07)

Primary citation

Athanasiadis, A.,Anderluh, G.,Macek, P.,Turk, D.
Crystal structure of the soluble form of equinatoxin II, a pore-forming toxin from the sea anemone Actinia equina.
Structure, 9:341-346, 2001

PubMed Abstract: Membrane pore-forming toxins have a remarkable property: they adopt a stable soluble form structure, which, when in contact with a membrane, undergoes a series of transformations, leading to an active, membrane-bound form. In contrast to bacterial toxins, no structure of a pore-forming toxin from an eukaryotic organism has been determined so far, an indication that structural studies of equinatoxin II (EqtII) may unravel a novel mechanism.

PubMed: 11525171
DOI: 10.1016/S0969-2126(01)00592-5

Experimental method

X-RAY DIFFRACTION (1.9 Å)