PDB: 2596 resultsInfo pagesStatus searchChemie searchBIRD

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2RLY	FBP28WW2 domain in complex with PTPPPLPP peptide Descriptor: Formin-1, Transcription elongation regulator 1 Authors: Ramirez-Espain, X, Ruiz, L, Martin-Malpartida, P, Oschkinat, H, Macias, M.J. Deposit date: 2007-09-03 Release date: 2007-11-06 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural Characterization of a New Binding Motif and a Novel Binding Mode in Group 2 WW Domains J.Mol.Biol., 373, 2007
2OEN	Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors glucose-6-phosphate and fructose-1,6-bisphosphate Descriptor: Catabolite control protein, Phosphocarrier protein HPr Authors: Schumacher, M.A, Seidel, G, Hillen, W, Brennan, R.G. Deposit date: 2006-12-30 Release date: 2007-05-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.17 Å) Cite: Structural Mechanism for the Fine-tuning of CcpA Function by The Small Molecule Effectors Glucose 6-Phosphate and Fructose 1,6-Bisphosphate. J.Mol.Biol., 368, 2007
8FKF	Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR36706 Descriptor: 1,2-ETHANEDIOL, 2-chloro-N-(5-fluoropyridin-3-yl)-5-nitrobenzamide, GLYCEROL, ... Authors: MacTavish, B.S, Kojetin, D.J. Deposit date: 2022-12-21 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and SR36706 To Be Published
1PFB	Structural Basis for specific binding of polycomb chromodomain to histone H3 methylated at K27 Descriptor: ACETIC ACID, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... Authors: Min, J.R, Zhang, Y, Xu, R.-M. Deposit date: 2003-05-24 Release date: 2003-10-07 Last modified: 2017-10-11 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27. Genes Dev., 17, 2003
8FKD	Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR33068 Descriptor: 1,2-ETHANEDIOL, 2-chloro-N-(6-cyanopyridin-3-yl)-5-nitrobenzamide, Nuclear receptor corepressor 1, ... Authors: MacTavish, B.S, Kojetin, D.J. Deposit date: 2022-12-21 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and SR33068 To Be Published
8FKG	Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR33486 Descriptor: 1,2-ETHANEDIOL, 2-chloro-N-(5-cyanopyridin-2-yl)-5-nitrobenzamide, GLYCEROL, ... Authors: MacTavish, B.S, Kojetin, D.J. Deposit date: 2022-12-21 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and SR33486 To Be Published
8FKC	Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR33544 Descriptor: 1,2-ETHANEDIOL, 2-chloro-N-(5-cyanopyridin-3-yl)-5-nitrobenzamide, Nuclear receptor corepressor 1, ... Authors: MacTavish, B.S, Kojetin, D.J. Deposit date: 2022-12-21 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and SR33544 To Be Published
8FKE	Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR32904 Descriptor: 1,2-ETHANEDIOL, 2-chloro-N-(2-methylpyridin-4-yl)-5-nitrobenzamide, Nuclear receptor corepressor 1, ... Authors: MacTavish, B.S, Kojetin, D.J. Deposit date: 2022-12-21 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and SR32904 To Be Published
8FHE	Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and GW9662 Descriptor: 2-chloro-5-nitro-N-phenylbenzamide, Nuclear receptor corepressor 1, Peroxisome proliferator-activated receptor gamma Authors: Shang, J, Kojetin, D.J. Deposit date: 2022-12-14 Release date: 2024-03-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and GW9662 To Be Published
8FHG	Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and ZINC5672437 Descriptor: N-(4-carbamoylphenyl)-2-chloro-5-nitrobenzamide, Nuclear receptor corepressor 1, Peroxisome proliferator-activated receptor gamma Authors: Shang, J, Kojetin, D.J. Deposit date: 2022-12-14 Release date: 2024-03-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and ZINC5672437 To Be Published
8FQJ	LSD1-CoREST in complex with T14, short soaking Descriptor: Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2S,3R,4R)-2,3,4-trihydroxy-5-[(1R,3S,3aS,13R)-1-hydroxy-10,11-dimethyl-3-{4-[(5-methyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl}-4,6-dioxo-2,3,5,6-tetrahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]pentyl dihydrogen diphosphate Authors: Caroli, J, Mattevi, A. Deposit date: 2023-01-06 Release date: 2024-06-26 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 To be published
8FDV	LSD1-CoREST in complex N-formyl FAD and SNAG peptide Descriptor: Lysine-specific histone demethylase 1A, REST corepressor 1, Zinc finger protein SNAI1, ... Authors: Caroli, J, Mattevi, A. Deposit date: 2022-12-05 Release date: 2024-06-12 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 to be published
8FJ6	LSD1-CoREST in complex with T108, long soaking Descriptor: Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-[7,8-dimethyl-2,4-dioxo-5-{3-[3-(phenylcarbamoyl)phenyl]propanoyl}-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate Authors: Caroli, J, Mattevi, A. Deposit date: 2022-12-19 Release date: 2024-06-26 Method: X-RAY DIFFRACTION (2.63 Å) Cite: Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 to be published
2OV7	The first domain of the ribosomal protein L1 from Thermus thermophilus Descriptor: 50S ribosomal protein L1 Authors: Kljashtorny, V, Tishchenko, S, Nevskaya, N, Nikonov, S, Davydova, N, Garber, M. Deposit date: 2007-02-13 Release date: 2007-12-25 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Domain I of ribosomal protein L1 is sufficient for specific RNA binding. Nucleic Acids Res., 35, 2007
1MVT	Analysis of Two Polymorphic Forms of a Pyrido[2,3-d]pyrimidine N9-C10 Reverse-Bridge Antifolate Binary Complex with Human Dihydrofolate Reductase Descriptor: 2,4-DIAMINO-6-[N-(3',4',5'-TRIMETHOXYBENZYL)-N-METHYLAMINO]PYRIDO[2,3-D]PYRIMIDINE, Dihydrofolate Reductase, SULFATE ION Authors: Cody, V, Galitsky, N, Luft, J.R, Pangborn, W.A, Gangjee, A. Deposit date: 2002-09-26 Release date: 2003-04-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Analysis of two polymorphic forms of a pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolate binary complex with human dihydrofolate reductase. Acta Crystallogr.,Sect.D, 59, 2003
8FJ4	LSD1-CoREST in complex with T108, short soaking Descriptor: 3-[(1R,2S)-2-(cyclobutylamino)cyclopropyl]-N-phenylbenzamide, Lysine-specific histone demethylase 1A, REST corepressor 1, ... Authors: Caroli, J, Mattevi, A. Deposit date: 2022-12-19 Release date: 2024-06-26 Method: X-RAY DIFFRACTION (2.76 Å) Cite: Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 to be published
8FJ7	LSD1-CoREST in complex with T108 and SNAG peptide Descriptor: Lysine-specific histone demethylase 1A, REST corepressor 1, Zinc finger protein SNAI1, ... Authors: Caroli, J, Mattevi, A. Deposit date: 2022-12-19 Release date: 2024-06-26 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 to be published
8HCU	Crystal structure of BCOR/PCGF1/KDM2B complex Descriptor: ACETIC ACID, BCL-6 corepressor, Polycomb group RING finger protein 1, ... Authors: Shen, F, Chen, R, Xu, J, Liu, J. Deposit date: 2022-11-03 Release date: 2023-11-15 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of BCOR/PCGF1/KDM2B complex to be published
1MVS	Analysis of Two Polymorphic Forms of a Pyrido[2,3-d]pyrimidine N9-C10 Reverse-Bridge Antifolate Binary Complex with Human Dihydrofolate Reductase Descriptor: 2,4-DIAMINO-6-[N-(3',4',5'-TRIMETHOXYBENZYL)-N-METHYLAMINO]PYRIDO[2,3-D]PYRIMIDINE, Dihydrofolate Reductase, SULFATE ION Authors: Cody, V, Galitsky, N, Luft, J.R, Pangborn, W.A, Gangjee, A. Deposit date: 2002-09-26 Release date: 2003-04-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Analysis of two polymorphic forms of a pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolate binary complex with human dihydrofolate reductase. Acta Crystallogr.,Sect.D, 59, 2003
6XZZ	Crystal structure of the BCL6 BTB domain in complex with the NCoR1 BBD2 peptide Descriptor: B-cell lymphoma 6 protein, CHLORIDE ION, Nuclear receptor corepressor 1, ... Authors: Zacharchenko, T, Wright, S.C. Deposit date: 2020-02-05 Release date: 2020-12-02 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.39 Å) Cite: Functionalization of the BCL6 BTB domain into a noncovalent crystallization chaperone. Iucrj, 8, 2021
8Q1H	LSD1 Y391K-CoREST bound to Histone H3 N-terminal tail Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.3C, Lysine-specific histone demethylase 1A, ... Authors: Barone, M, Mattevi, A. Deposit date: 2023-07-31 Release date: 2024-05-15 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nat.Chem.Biol., 2024
8Q1G	LSD1-CoREST bound to Acetylated K14 of Histone H3 Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.3C, Lysine-specific histone demethylase 1A, ... Authors: Barone, M, Mattevi, A. Deposit date: 2023-07-31 Release date: 2024-05-15 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nat.Chem.Biol., 2024
8Q1J	LSD1 Y391K-CoREST bound to Acetylated K14 of Histone H3 Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.3C, Lysine-specific histone demethylase 1A, ... Authors: Barone, M, Mattevi, A. Deposit date: 2023-07-31 Release date: 2024-05-15 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (2.87 Å) Cite: Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nat.Chem.Biol., 2024
6W9K	Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with Prednisolone and PGC1a coregulator fragment Descriptor: GLYCEROL, Glucocorticoid Receptor, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ... Authors: Liu, X, Ortlund, E.A. Deposit date: 2020-03-23 Release date: 2020-11-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment. Proc.Natl.Acad.Sci.USA, 117, 2020
4O8B	Crystal structure of transcriptional regulator BswR Descriptor: Uncharacterized protein Authors: Ye, F.Z, Wang, C, Kumar, V, Zhang, L.H, Gao, Y.G. Deposit date: 2013-12-26 Release date: 2014-02-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: BswR controls bacterial motility and biofilm formation in Pseudomonas aeruginosa through modulation of the small RNA rsmZ. Nucleic Acids Res., 42, 2014

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