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8FHE

Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and GW9662

Summary for 8FHE
Entry DOI10.2210/pdb8fhe/pdb
DescriptorPeroxisome proliferator-activated receptor gamma, Nuclear receptor corepressor 1, 2-chloro-5-nitro-N-phenylbenzamide, ... (4 entities in total)
Functional Keywordsnuclear receptors, tzds, drug design, therapeutic targets, transcription, transcription-agonist complex
Biological sourceHomo sapiens (human)
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Total number of polymer chains2
Total formula weight34235.02
Authors
Shang, J.,Kojetin, D.J. (deposition date: 2022-12-14, release date: 2024-03-20)
Primary citationShang, J.,Kojetin, D.J.
Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and GW9662
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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PDB entries from 2024-04-24

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