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1RAU	SOLUTION STRUCTURE OF AN UNUSUALLY STABLE RNA TETRAPLEX CONTAINING G-AND U-QUARTET STRUCTURES Descriptor: RNA (5'-R(*UP*GP*GP*GP*GP*U)-3') Authors: Cheong, C, Moore, P.B. Deposit date: 1993-07-29 Release date: 1994-01-31 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution structure of an unusually stable RNA tetraplex containing G- and U-quartet structures. Biochemistry, 31, 1992
7YOT	Cryo-EM structure of RNA polymerase in complex with P protein tetramer of Newcastle disease virus Descriptor: NDV P protein, RNA-directed RNA polymerase L Authors: Chen, Y, Jingyuan, C. Deposit date: 2022-08-02 Release date: 2023-02-15 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein. Nat Commun, 14, 2023
7YOU	Cryo-EM structure of RNA polymerase in complex with P protein tetramer of Newcastle disease virus Descriptor: NDV P protein, RNA-directed RNA polymerase L Authors: Chen, Y, Jingyuan, C, Xiaoying, F. Deposit date: 2022-08-02 Release date: 2023-02-15 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (3.41 Å) Cite: Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein. Nat Commun, 14, 2023
7YOV	Cryo-EM structure of RNA polymerase in complex with P protein tetramer of Newcastle disease virus Descriptor: NDV P protein, RNA-directed RNA polymerase L Authors: Chen, Y, Jingyuan, C, Xiaoying, F. Deposit date: 2022-08-02 Release date: 2023-02-15 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (3.25 Å) Cite: Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein. Nat Commun, 14, 2023
1BE1	GLUTAMATE MUTASE (B12-BINDING SUBUNIT), NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: GLUTAMATE MUTASE Authors: Tollinger, M, Konrat, R, Hilbert, B.H, Marsh, E.N.G, Kraeutler, B. Deposit date: 1998-05-19 Release date: 1998-08-26 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: How a protein prepares for B12 binding: structure and dynamics of the B12-binding subunit of glutamate mutase from Clostridium tetanomorphum Structure, 6, 1998
1ORW	Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26) in Complex with a Peptidomimetic Inhibitor Descriptor: (2S)-PYRROLIDIN-2-YLMETHYLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Engel, M, Hoffmann, T, Wagner, L, Wermann, M, Heiser, U, Kiefersauer, R, Huber, R, Bode, W, Demuth, H.U, Brandstetter, H. Deposit date: 2003-03-16 Release date: 2003-05-06 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.84 Å) Cite: The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals its Functional Regulation and Enzymatic Mechanism Proc.Natl.Acad.Sci.USA, 100, 2003
5M4W	Structure of DNA AGCGA-quadruplex adopted by 15-mer oligonucleotide found in regulatory region of the PLEKHG3 human gene with G11 to I11 mutation, d(GCGAGGGAGCIAGGG),VK34_I11 Descriptor: DNA (5'-D(*GP*CP*GP*AP*GP*GP*GP*AP*GP*CP*IP*AP*GP*GP*G)-3') Authors: Kocman, V, Plavec, J. Deposit date: 2016-10-19 Release date: 2017-05-31 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Tetrahelical structural family adopted by AGCGA-rich regulatory DNA regions. Nat Commun, 8, 2017
2WQJ	Crystal structure of a truncated variant of the human p73 tetramerization domain Descriptor: TUMOR PROTEIN P73 Authors: Joerger, A.C. Deposit date: 2009-08-21 Release date: 2009-10-06 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation. Proc.Natl.Acad.Sci.USA, 106, 2009
1H5V	Thiopentasaccharide complex of the endoglucanase Cel5A from Bacillus agaradharens at 1.1 A resolution in the tetragonal crystal form Descriptor: CALCIUM ION, ENDOGLUCANASE 5A, SODIUM ION, ... Authors: Varrot, A, Sulzenbacher, G, Schulein, M, Driguez, H, Davies, G.J. Deposit date: 2001-05-28 Release date: 2002-05-23 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Atomic Resolution Structure of Endoglucanase Cel5A in Complex with Methyl 4,4II,4III,4Iv-Tetrathio-Alpha-Cellopentoside Highlights the Alternative Binding Modes Targeted by Substrate Mimics Acta Crystallogr.,Sect.D, 57, 2001
2WQI	Crystal structure of the human p73 tetramerization domain Descriptor: TUMOR PROTEIN P73 Authors: Joerger, A.C. Deposit date: 2009-08-21 Release date: 2009-10-06 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation. Proc.Natl.Acad.Sci.USA, 106, 2009
1WNT	Structure of the tetrameric form of Human L-Xylulose Reductase Descriptor: L-xylulose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: El-Kabbani, O, Carbone, V, Darmanin, C, Ishikura, S, Hara, A. Deposit date: 2004-08-09 Release date: 2005-07-19 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of the tetrameric form of human L-Xylulose reductase: Probing the inhibitor-binding site with molecular modeling and site-directed mutagenesis Proteins, 60, 2005
7JUP	Structure of human TRPA1 in complex with antagonist compound 21 Descriptor: 1-({3-[(3R,5R)-5-(4-fluorophenyl)oxolan-3-yl]-1,2,4-oxadiazol-5-yl}methyl)-7-methyl-1,7-dihydro-6H-purin-6-one, Transient receptor potential cation channel subfamily A member 1 Authors: Rohou, A, Rouge, L. Deposit date: 2020-08-20 Release date: 2021-03-31 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.05 Å) Cite: Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy. J.Med.Chem., 64, 2021
2WTT	Structure of the human p73 tetramerization domain (crystal form II) Descriptor: TUMOR PROTEIN P73 Authors: Joerger, A.C. Deposit date: 2009-09-21 Release date: 2009-10-13 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation. Proc.Natl.Acad.Sci.USA, 106, 2009
352D	THE CRYSTAL STRUCTURE OF A PARALLEL-STRANDED PARALLEL-STRANDED GUANINE TETRAPLEX AT 0.95 ANGSTROM RESOLUTION Descriptor: CALCIUM ION, DNA (5'-D(*TP*GP*GP*GP*GP*T)-3'), SODIUM ION Authors: Phillips, K, Dauter, Z, Murchie, A.I.H, Lilley, D.M.J, Luisi, B. Deposit date: 1997-09-04 Release date: 1997-11-10 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (0.95 Å) Cite: The crystal structure of a parallel-stranded guanine tetraplex at 0.95 A resolution. J.Mol.Biol., 273, 1997
1ORV	Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... Authors: Engel, M, Hoffmann, T, Wagner, L, Wermann, M, Heiser, U, Kiefersauer, R, Huber, R, Bode, W, Demuth, H.U, Brandstetter, H. Deposit date: 2003-03-16 Release date: 2003-05-06 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals its Functional Regulation and Enzymatic Mechanism Proc.Natl.Acad.Sci.USA, 100, 2003
5MS4	Kallikrein-related peptidase 8 leupeptin inhibitor complex Descriptor: CALCIUM ION, Kallikrein-8, LEUPEPTIN, ... Authors: Debela, M, Magdolen, V, Skala, W, Bode, W, Brandstetter, H, Goettig, P. Deposit date: 2016-12-30 Release date: 2018-01-17 Last modified: 2019-10-09 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin. Sci Rep, 8, 2018
1EMQ	NMR OBSERVATION OF T-TETRADS IN A PARALLEL STRANDED DNA QUADRUPLEX FORMED BY SACCHAROMYCES CEREVISIAE TELOMERE REPEATS Descriptor: DNA (5'-D(*TP*GP*GP*TP*GP*GP*C)-3') Authors: Hosur, R.V, Patel, P.K. Deposit date: 2000-03-17 Release date: 2000-04-04 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: NMR observation of T-tetrads in a parallel stranded DNA quadruplex formed by Saccharomyces cerevisiae telomere repeats. Nucleic Acids Res., 27, 1999
5O7E	Crystal structure of the peptidase domain of collagenase H from Clostridium histolyticum in complex with N-aryl mercaptoacetamide-based inhibitor Descriptor: CALCIUM ION, ColH protein, ZINC ION, ... Authors: Schoenauer, E, Brandstetter, H. Deposit date: 2017-06-08 Release date: 2018-01-31 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Discovery of a Potent Inhibitor Class with High Selectivity toward Clostridial Collagenases. J. Am. Chem. Soc., 139, 2017
244D	THE HIGH-RESOLUTION CRYSTAL STRUCTURE OF A PARALLEL-STRANDED GUANINE TETRAPLEX Descriptor: CALCIUM ION, DNA (5'-D(*TP*GP*GP*GP*GP*T)-3'), SODIUM ION Authors: Laughlan, G, Murchie, A.I.H, Norman, D.G, Moore, M.H, Moody, P.C.E, Lilley, D.M.J, Luisi, B. Deposit date: 1995-10-19 Release date: 1996-02-23 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.2 Å) Cite: The high-resolution crystal structure of a parallel-stranded guanine tetraplex. Science, 265, 1994
1EVM	NMR OBSERVATION OF A-TETRAD Descriptor: DNA (5'-D(*AP*GP*GP*GP*T)-3') Authors: Patel, P.K, Koti, A.S.R, Hosur, R.V. Deposit date: 2000-04-20 Release date: 2000-05-22 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: NMR studies on truncated sequences of human telomeric DNA: observation of a novel A-tetrad. Nucleic Acids Res., 27, 1999
1NMS	Caspase-3 tethered to irreversible inhibitor Descriptor: 5-[4-(1-CARBOXYMETHYL-2-OXO-PROPYLCARBAMOYL)-BENZYLSULFAMOYL]-2-HYDROXY-BENZOIC ACID, Caspase-3 Authors: Erlanson, D.A, Lam, J, Wiesmann, C, Luong, T.N, Simmons, R.L, DeLano, W.L, Choong, I.C, Flanagan, W.M, Lee, D, O'Brian, T. Deposit date: 2003-01-10 Release date: 2003-03-11 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.7 Å) Cite: In situ assembly of enzyme inhibitors using extended tethering. Nat.Biotechnol., 21, 2003
1NME	Structure of Casp-3 with tethered salicylate Descriptor: 2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID, 3-(2-MERCAPTO-ACETYLAMINO)-4-OXO-PENTANOIC ACID, Caspase-3 Authors: Erlanson, D.A, Lam, J, Wiesmann, C, Luong, T.N, Simmons, B, DeLano, W, Choong, I.C, Flanagan, M, Lee, D, O'Brian, T. Deposit date: 2003-01-09 Release date: 2003-03-11 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.6 Å) Cite: In situ assembly of enzyme inhibitors using extended tethering. Nat.Biotechnol., 21, 2003
1EVO	NMR OBSERVATION OF A NOVEL C-TETRAD Descriptor: DNA (5'-D(*TP*GP*GP*GP*CP*GP*GP*T)-3') Authors: Patel, P.K, Bhavesh, N.S, Hosur, R.V. Deposit date: 2000-04-20 Release date: 2000-05-01 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: NMR observation of a novel C-tetrad in the structure of the SV40 repeat sequence GGGCGG. Biochem.Biophys.Res.Commun., 270, 2000
1EVN	NMR OBSERVATION OF A-TETRAD Descriptor: DNA (5'-D(*AP*GP*GP*GP*T)-3') Authors: Patel, P.K, Koti, A.S.R, Hosur, R.V. Deposit date: 2000-04-20 Release date: 2000-05-22 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: NMR studies on truncated sequences of human telomeric DNA: observation of a novel A-tetrad. Nucleic Acids Res., 27, 1999
1Z7J	Human transthyretin (also called prealbumin) complex with 3, 3',5,5'-tetraiodothyroacetic acid (t4ac) Descriptor: 3,3',5,5'-TETRAIODOTHYROACETIC ACID, Transthyretin Authors: Neumann, P, Wojtczak, A, Cody, V. Deposit date: 2005-03-25 Release date: 2005-06-07 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Ligand binding at the transthyretin dimer-dimer interface: structure of the transthyretin-T4Ac complex at 2.2 Angstrom resolution. Acta Crystallogr.,Sect.D, 61, 2005

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