5M4W

Structure of DNA AGCGA-quadruplex adopted by 15-mer oligonucleotide found in regulatory region of the PLEKHG3 human gene with G11 to I11 mutation, d(GCGAGGGAGCIAGGG),VK34_I11

Summary for 5M4W

• Entry DOI: 10.2210/pdb5m4w/pdb
• NMR Information: BMRB: 34056
• Descriptor: DNA (5'-D(*GP*CP*GP*AP*GP*GP*GP*AP*GP*CP*IP*AP*GP*GP*G)-3') (1 entity in total)
• Functional Keywords: agcga-quadruplex, agcga-quadruplex family, g-g n1-carboniyl symmetric base pair, plekhg3 gene, dna, inosine
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 9500.14

Authors

Kocman, V.,Plavec, J. (deposition date: 2016-10-19, release date: 2017-05-31, Last modification date: 2019-05-08)

• Primary citation: Kocman, V.,Plavec, J.; Tetrahelical structural family adopted by AGCGA-rich regulatory DNA regions.; Nat Commun, 8:15355-15355, 2017; PubMed: 28513602; DOI: 10.1038/ncomms15355

Experimental method

SOLUTION NMR