PDB: 2624 resultsInfo pagesStatus searchChemie searchBIRD

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8GIR	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.2mM Mn2+ Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-03-14 Release date: 2024-04-17 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIO	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.1mM Mn2+ Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-03-14 Release date: 2024-04-17 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.67 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIT	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 1mM Mn2+ Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-03-14 Release date: 2024-04-17 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.72 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
4YXM	Structure of Thermotoga maritima DisA D75N mutant with reaction product c-di-AMP Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, (4S)-2-METHYL-2,4-PENTANEDIOL, DNA integrity scanning protein DisA Authors: Mueller, M, Deimling, T, Hopfner, K.-P, Witte, G. Deposit date: 2015-03-23 Release date: 2015-06-03 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural analysis of the diadenylate cyclase reaction of DNA-integrity scanning protein A (DisA) and its inhibition by 3'-dATP. Biochem.J., 469, 2015
4YXJ	Structure of Thermotoga maritima DisA in complex with ApCpp Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA integrity scanning protein DisA Authors: Mueller, M, Deimling, T, Hopfner, K.-P, Witte, G. Deposit date: 2015-03-23 Release date: 2015-06-03 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structural analysis of the diadenylate cyclase reaction of DNA-integrity scanning protein A (DisA) and its inhibition by 3'-dATP. Biochem.J., 469, 2015
4U0M	Structure of the Vibrio cholerae di-nucleotide cyclase (DncV) mutant D193N in complex with ATP, GTP and 5MTHFGLU2 Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic AMP-GMP synthase, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Zhu, D, Xiang, Y. Deposit date: 2014-07-12 Release date: 2014-09-17 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural Biochemistry of a Vibrio cholerae Dinucleotide Cyclase Reveals Cyclase Activity Regulation by Folates. Mol.Cell, 55, 2014
1WY5	Crystal structure of isoluecyl-tRNA lysidine synthetase Descriptor: Hypothetical UPF0072 protein AQ_1887 Authors: Nakanishi, K, Fukai, S, Ikeuchi, Y, Soma, A, Sekine, Y, Suzuki, T, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-02-06 Release date: 2005-05-03 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain. Proc.Natl.Acad.Sci.Usa, 102, 2005
8GIN	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.015mM Mn2+ Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-03-14 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.75 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIM	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-03-14 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.63 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8G1J	Structure of Ternary Complex of cGAS with dsDNA and Bound ATP and ITP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-02-02 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIP	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.040mM Mn2+ Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-03-14 Release date: 2024-05-22 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
3FEM	Structure of the synthase subunit Pdx1.1 (Snz1) of PLP synthase from Saccharomyces cerevisiae Descriptor: Pyridoxine biosynthesis protein SNZ1 Authors: Strohmeier, M, Windeisen, V, Sinning, I, Tews, I. Deposit date: 2008-11-30 Release date: 2009-06-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.02 Å) Cite: X-ray crystal structure of Saccharomyces cerevisiae Pdx1 provides insights into the oligomeric nature of PLP synthases. Febs Lett., 583, 2009
8GZU	Cryo-EM structure of Tetrahymena thermophila respiratory Megacomplex MC (IV2+I+III2+II)2 Descriptor: 2 iron, 2 sulfur cluster-binding protein, 2-oxoglutarate/malate carrier protein, ... Authors: Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L. Deposit date: 2022-09-27 Release date: 2023-06-14 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (4.18 Å) Cite: Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae. Nat Commun, 14, 2023
8GYM	Cryo-EM structure of Tetrahymena thermophila respiratory mega-complex MC IV2+(I+III2+II)2 Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... Authors: Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L. Deposit date: 2022-09-23 Release date: 2023-06-14 Last modified: 2024-10-30 Method: ELECTRON MICROSCOPY (2.96 Å) Cite: Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae. Nat Commun, 14, 2023
3FPA	Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase complexed with dethiobiotin and phosphate Descriptor: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, Dethiobiotin synthetase, MAGNESIUM ION, ... Authors: Dey, S, Sacchettini, J.C. Deposit date: 2009-01-04 Release date: 2009-06-30 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase. Biochemistry, 49, 2010
6PK7	cryoEM structure of the product-bound human CTP synthase 2 filament Descriptor: ADENOSINE-5'-DIPHOSPHATE, CTP synthase 2, CYTIDINE-5'-TRIPHOSPHATE Authors: Lynch, E.M, Kollman, J.M. Deposit date: 2019-06-28 Release date: 2019-12-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Coupled structural transitions enable highly cooperative regulation of human CTPS2 filaments. Nat.Struct.Mol.Biol., 27, 2020
3FGN	Crystal structure of dethiobiotin synthetase in Mycobacterium tuberculosis Descriptor: Dethiobiotin synthetase Authors: Dey, S, Sacchettini, J.C. Deposit date: 2008-12-08 Release date: 2009-06-30 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase . Biochemistry, 49, 2010
8I1M	Crystal structure of oxidated APSK1 domain from human PAPSS1 in complex with APS and ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-PHOSPHOSULFATE, PAPSS1 protein, ... Authors: Zhang, L, Song, W.Y, Zhang, L. Deposit date: 2023-01-13 Release date: 2023-06-28 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.699 Å) Cite: Redox switching mechanism of the adenosine 5'-phosphosulfate kinase domain (APSK2) of human PAPS synthase 2. Structure, 31, 2023
4YCW	Crystal structure of cladosporin in complex with plasmodium like human lysyl-tRNA synthetase mutant Descriptor: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, LYSINE, Lysine--tRNA ligase, ... Authors: Fang, P, Wang, J, Guo, M. Deposit date: 2015-02-20 Release date: 2015-06-10 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural Basis for Specific Inhibition of tRNA Synthetase by ATP Competitive Inhibitor Chem.Biol., 22, 2015
2NZ2	Crystal structure of human argininosuccinate synthase in complex with aspartate and citrulline Descriptor: ASPARTIC ACID, Argininosuccinate synthase, CITRULLINE, ... Authors: Karlberg, T, Uppenberg, J, Arrowsmith, C, Berglund, H, Busam, R.D, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Hogbom, M, Johansson, I, Kotenyova, T, Magnusdottir, A, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) Deposit date: 2006-11-22 Release date: 2006-12-05 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure of human argininosuccinate synthetase. Acta Crystallogr.,Sect.D, 64, 2008
3FMI	Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase complexed with 7-Keto 8-aminopelargonic acid Descriptor: 7-KETO-8-AMINOPELARGONIC ACID, Dethiobiotin synthetase, SULFATE ION Authors: Dey, S, Sacchettini, J.C. Deposit date: 2008-12-22 Release date: 2009-06-30 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase . Biochemistry, 49, 2010
1VCO	Crystal Structure of T.th. HB8 CTP synthetase complex with Glutamine Descriptor: CTP synthetase, GLUTAMINE Authors: Goto, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2004-03-10 Release date: 2004-08-31 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal Structures of CTP Synthetase Reveal ATP, UTP, and Glutamine Binding Sites Structure, 12, 2004
1VCM	Crystal Structure of T.th. HB8 CTP synthetase Descriptor: CTP synthetase Authors: Goto, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2004-03-10 Release date: 2004-08-31 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal Structures of CTP Synthetase Reveal ATP, UTP, and Glutamine Binding Sites Structure, 12, 2004
1VCN	Crystal Structure of T.th. HB8 CTP synthetase complex with Sulfate anion Descriptor: CTP synthetase, SULFATE ION Authors: Goto, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2004-03-10 Release date: 2004-08-31 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Crystal Structures of CTP Synthetase Reveal ATP, UTP, and Glutamine Binding Sites Structure, 12, 2004
3FMF	Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase complexed with 7,8 diaminopelargonic acid carbamate Descriptor: 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID, Dethiobiotin synthetase Authors: Dey, S, Sacchettini, J.C. Deposit date: 2008-12-21 Release date: 2009-06-30 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase . Biochemistry, 49, 2010

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