2H12
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2HE0
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![BU of 2he0 by Molmil](/molmil-images/mine/2he0) | Crystal structure of a human Notch1 ankyrin domain mutant | Descriptor: | 1,2-ETHANEDIOL, Notch1 preproprotein variant | Authors: | Gupta, D, Ehebauer, M.T, Chirgadze, D.Y, Martinez Arias, A, Blundell, T.L. | Deposit date: | 2006-06-21 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of a human Notch1 ankyrin domain mutant TO BE PUBLISHED
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2H4Z
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7D5G
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2GJT
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![BU of 2gjt by Molmil](/molmil-images/mine/2gjt) | Crystal structure of the human receptor phosphatase PTPRO | Descriptor: | CHLORIDE ION, Receptor-type tyrosine-protein phosphatase PTPRO | Authors: | Barr, A, Ugochukwu, E, Eswaran, J, Das, S, Niesen, F, Savitsky, P, Turnbull, A, Sundstrom, M, Arrowsmith, C, Edwards, A, Weigelt, J, von Delft, F, Papagrigoriou, E, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2006-03-31 | Release date: | 2006-05-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Large-scale structural analysis of the classical human protein tyrosine phosphatome. Cell(Cambridge,Mass.), 136, 2009
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2GK7
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![BU of 2gk7 by Molmil](/molmil-images/mine/2gk7) | Structural and Functional insights into the human Upf1 helicase core | Descriptor: | PHOSPHATE ION, Regulator of nonsense transcripts 1 | Authors: | Cheng, Z, Muhlrad, D, Parker, R, Song, H. | Deposit date: | 2006-03-31 | Release date: | 2007-01-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and functional insights into the human Upf1 helicase core Embo J., 26, 2007
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2GO1
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![BU of 2go1 by Molmil](/molmil-images/mine/2go1) | NAD-dependent formate dehydrogenase from Pseudomonas sp.101 | Descriptor: | NAD-dependent formate dehydrogenase, SULFATE ION | Authors: | Filippova, E.V, Polyakov, K.M, Tikhonova, T.V, Stekhanova, T.N, Boiko, K.M, Popov, V.O. | Deposit date: | 2006-04-12 | Release date: | 2006-05-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of a new crystal modification of the bacterial NAD-dependent formate dehydrogenase with a resolution of 2.1 A Crystallography reports, 50, 2005
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2GKU
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![BU of 2gku by Molmil](/molmil-images/mine/2gku) | Monomeric human telomere DNA tetraplex with 3+1 strand fold topology, two edgewise loops and double-chain reversal loop, NMR, 12 structures | Descriptor: | Human telomere DNA | Authors: | Luu, K.N, Phan, A.T, Kuryavyi, V.V, Lacroix, L, Patel, D.J. | Deposit date: | 2006-04-03 | Release date: | 2006-08-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of the human telomere in k(+) solution: an intramolecular (3 + 1) g-quadruplex scaffold. J.Am.Chem.Soc., 128, 2006
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7DLH
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7DK2
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![BU of 7dk2 by Molmil](/molmil-images/mine/7dk2) | Crystal structure of SARS-CoV-2 Spike RBD in complex with MW07 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MW07 heavy chain, MW07 light chain, ... | Authors: | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M, Chen, S. | Deposit date: | 2020-11-22 | Release date: | 2021-12-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Architectural versatility of spike neutralization by a SARS-CoV-2 antibody To Be Published
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6LX1
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![BU of 6lx1 by Molmil](/molmil-images/mine/6lx1) | Potato D-enzyme complexed with Acarbose | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-1,5-anhydro-D-glucitol, 4-alpha-glucanotransferase, chloroplastic/amyloplastic, ... | Authors: | Unno, H, Imamura, K. | Deposit date: | 2020-02-10 | Release date: | 2020-08-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural analysis and reaction mechanism of the disproportionating enzyme (D-enzyme) from potato. Protein Sci., 29, 2020
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6M8P
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![BU of 6m8p by Molmil](/molmil-images/mine/6m8p) | Human ERAP1 bound to phosphinic pseudotripeptide inhibitor DG013 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Endoplasmic reticulum aminopeptidase 1, Nalpha-[(2S)-2-{[[(1R)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]methyl}-4-methylpentanoyl]-L-tryptophanamide, ... | Authors: | Maben, Z, Stern, L.J. | Deposit date: | 2018-08-22 | Release date: | 2019-12-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism. Nat Commun, 12, 2021
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6LSA
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![BU of 6lsa by Molmil](/molmil-images/mine/6lsa) | Complex structure of bovine herpesvirus 1 glycoprotein D and bovine nectin-1 IgV | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D, ... | Authors: | Yue, D, Chen, Z.J, Yang, F.L, Ye, F, Lin, S, Cheng, Y.W, Wang, J.C, Chen, Z.M, Lin, X, Yang, J, Chen, H, Zhang, Z.L, You, Y, Sun, H.L, Wen, A, Wang, L.L, Zheng, Y, Cao, Y, Li, Y.H, Lu, G.W. | Deposit date: | 2020-01-17 | Release date: | 2020-06-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.204 Å) | Cite: | Crystal structure of bovine herpesvirus 1 glycoprotein D bound to nectin-1 reveals the basis for its low-affinity binding to the receptor. Sci Adv, 6, 2020
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6LGI
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6DLP
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![BU of 6dlp by Molmil](/molmil-images/mine/6dlp) | Crystal structure of LRRK2 WD40 domain dimer | Descriptor: | Leucine-rich repeat serine/threonine-protein kinase 2, PLATINUM (II) ION | Authors: | Zhang, P, Ru, H, Wang, L, Wu, H. | Deposit date: | 2018-06-02 | Release date: | 2019-01-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Crystal structure of the WD40 domain dimer of LRRK2. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6DM1
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![BU of 6dm1 by Molmil](/molmil-images/mine/6dm1) | Open state GluA2 in complex with STZ and blocked by NASPM, after micelle signal subtraction | Descriptor: | CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, ... | Authors: | Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I. | Deposit date: | 2018-06-04 | Release date: | 2018-08-22 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors. Neuron, 99, 2018
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6DNU
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4W7S
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![BU of 4w7s by Molmil](/molmil-images/mine/4w7s) | Crystal structure of the yeast DEAD-box splicing factor Prp28 at 2.54 Angstroms resolution | Descriptor: | GLYCEROL, HEXAETHYLENE GLYCOL, MAGNESIUM ION, ... | Authors: | Jacewicz, A, Smith, P, Schwer, B, Shuman, S. | Deposit date: | 2014-08-22 | Release date: | 2014-10-29 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.542 Å) | Cite: | Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28. Nucleic Acids Res., 42, 2014
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6DQ4
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![BU of 6dq4 by Molmil](/molmil-images/mine/6dq4) | LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR GSK-J1 | Descriptor: | 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Horton, J.R, Cheng, X. | Deposit date: | 2018-06-10 | Release date: | 2018-11-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.392 Å) | Cite: | Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A. J. Med. Chem., 61, 2018
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6DQI
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7Z36
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![BU of 7z36 by Molmil](/molmil-images/mine/7z36) | Crystal structure of the KAP1 tripartite motif in complex with the ZNF93 KRAB domain | Descriptor: | Endolysin,Transcription intermediary factor 1-beta,Isoform 2 of Transcription intermediary factor 1-beta, SMARCAD1 CUE1 domain, ZINC ION, ... | Authors: | Stoll, G.A, Modis, Y. | Deposit date: | 2022-03-01 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure and functional mapping of the KRAB-KAP1 repressor complex. Embo J., 41, 2022
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4W97
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![BU of 4w97 by Molmil](/molmil-images/mine/4w97) | Structure of ketosteroid transcriptional regulator KstR2 of Mycobacterium tuberculosis | Descriptor: | CHLORIDE ION, HTH-type transcriptional repressor KstR2, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 3-[(3aS,4S,7aS)-7a-methyl-1,5-bis(oxidanylidene)-2,3,3a,4,6,7-hexahydroinden-4-yl]propanethioate | Authors: | Stogios, P.J, Evdokimova, E, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-08-27 | Release date: | 2014-11-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and Functional Characterization of a Ketosteroid Transcriptional Regulator of Mycobacterium tuberculosis. J.Biol.Chem., 290, 2015
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4W9S
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![BU of 4w9s by Molmil](/molmil-images/mine/4w9s) | 2-(4-(1H-tetrazol-5-yl)phenyl)-5-hydroxypyrimidin-4(3H)-one bound to influenza 2009 H1N1 endonuclease | Descriptor: | 5-hydroxy-2-[4-(1H-tetrazol-5-yl)phenyl]pyrimidin-4(3H)-one, MANGANESE (II) ION, Polymerase acidic protein, ... | Authors: | Bauman, J.D, Patel, D, Das, K, Arnold, E. | Deposit date: | 2014-08-27 | Release date: | 2014-10-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Phenyl Substituted 4-Hydroxypyridazin-3(2H)-ones and 5-Hydroxypyrimidin-4(3H)-ones: Inhibitors of Influenza A Endonuclease. J.Med.Chem., 57, 2014
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6DT3
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![BU of 6dt3 by Molmil](/molmil-images/mine/6dt3) | 1.2 Angstrom Resolution Crystal Structure of Nucleoside Triphosphatase NudI from Klebsiella pneumoniae in Complex with HEPES | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Nucleoside triphosphatase NudI | Authors: | Minasov, G, Shuvalova, L, Pshenychnyi, S, Endres, M, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-06-15 | Release date: | 2018-06-27 | Last modified: | 2023-06-14 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae. Microbiol Resour Announc, 12, 2023
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7YQ3
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![BU of 7yq3 by Molmil](/molmil-images/mine/7yq3) | human insulin receptor bound with A43 DNA aptamer and insulin | Descriptor: | IR-A43 aptamer, Insulin A chain, Insulin, ... | Authors: | Kim, J, Yunn, N, Ryu, S, Cho, Y. | Deposit date: | 2022-08-05 | Release date: | 2022-11-09 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures. Nat Commun, 13, 2022
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