Crystal structure of the yeast DEAD-box splicing factor Prp28 at 2.54 Angstroms resolution

Summary for 4W7S

DescriptorPre-mRNA-splicing ATP-dependent RNA helicase PRP28, HEXAETHYLENE GLYCOL, GLYCEROL, ... (6 entities in total)
Functional Keywordssplicing factor, dead-box protein, atpase, hydrolase
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains2
Total molecular weight108887.37
Jacewicz, A.,Smith, P.,Schwer, B.,Shuman, S. (deposition date: 2014-08-22, release date: 2014-10-29, Last modification date: 2019-12-25)
Primary citation
Jacewicz, A.,Schwer, B.,Smith, P.,Shuman, S.
Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28.
Nucleic Acids Res., 42:12885-12898, 2014
PubMed: 25303995 (PDB entries with the same primary citation)
DOI: 10.1093/nar/gku930
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21980 1.6% 2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21