2HE0

Crystal structure of a human Notch1 ankyrin domain mutant

Summary for 2HE0

• Entry DOI: 10.2210/pdb2he0/pdb
• Related: 1YYH
• Descriptor: Notch1 preproprotein variant, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: notch, ankyrin, signalling, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Single-pass type I membrane protein (By similarity). Notch 1 intracellular domain: Nucleus (By similarity): P46531
• Total number of polymer chains: 2
• Total formula weight: 55331.45

Authors

Gupta, D.,Ehebauer, M.T.,Chirgadze, D.Y.,Martinez Arias, A.,Blundell, T.L. (deposition date: 2006-06-21, release date: 2006-07-04, Last modification date: 2023-08-30)

• Primary citation: Gupta, D.,Ehebauer, M.T.,Chirgadze, D.Y.,Martinez Arias, A.,Blundell, T.L.; Crystal structure of a human Notch1 ankyrin domain mutant; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (1.9 Å)