2ZP4
| Carboxylic ester hydrolase, single mutant h48n of bovine pancreatic pla2 enzyme | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Kanaujia, S.P, Sekar, K. | Deposit date: | 2008-06-27 | Release date: | 2008-11-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures and molecular-dynamics studies of three active-site mutants of bovine pancreatic phospholipase A(2) Acta Crystallogr.,Sect.D, 64, 2008
|
|
3R0L
| Crystal structure of crotoxin | Descriptor: | ACETATE ION, CHLORIDE ION, Crotoxin chain A, ... | Authors: | Saul, F.A, Faure, G. | Deposit date: | 2011-03-08 | Release date: | 2011-10-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Crystal Structure of Crotoxin Reveals Key Residues Involved in the Stability and Toxicity of This Potent Heterodimeric Beta-Neurotoxin J.Mol.Biol., 412, 2011
|
|
3QNL
| Crystal structure of PrTX-I complexed to Rosmarinic Acid | Descriptor: | (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ISOPROPYL ALCOHOL, ... | Authors: | dos Santos, J.I, Fontes, M.R.M. | Deposit date: | 2011-02-08 | Release date: | 2012-02-29 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA(2) Inhibition. Plos One, 6, 2011
|
|
3BJW
| Crystal Structure of ecarpholin S complexed with suramin | Descriptor: | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Phospholipase A2 | Authors: | Zhou, X, Sivaraman, J. | Deposit date: | 2007-12-04 | Release date: | 2007-12-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Characterization of Myotoxic Ecarpholin S from Echis carinatus Venom Biophys.J., 95, 2008
|
|
3BP2
| |
3U8B
| Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism | Descriptor: | CALCIUM ION, CHLORIDE ION, Phospholipase A2, ... | Authors: | Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F. | Deposit date: | 2011-10-16 | Release date: | 2012-10-17 | Last modified: | 2013-06-12 | Method: | X-RAY DIFFRACTION (2.299 Å) | Cite: | Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes. J.Biol.Chem., 288, 2013
|
|
4G5I
| Crystal Structure of Porcine pancreatic PlA2 in complex with DBP | Descriptor: | CALCIUM ION, CHLORIDE ION, Phospholipase A2, ... | Authors: | Prasanth, G.K, Naveen, C.D, Mandal, P.K, Karthe, P, Haridas, M, Sadasivan, C. | Deposit date: | 2012-07-18 | Release date: | 2012-11-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of Porcine pancreatic PlA2 in complex with DBP TO BE PUBLISHED
|
|
4GFY
| Design of peptide inhibitors of phospholipase A2: crystal Structure of phospholipase A2 complexed with a designed tetrapeptide Val - Ilu- Ala - Lys at 2.7 A resolution | Descriptor: | Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, VIAK | Authors: | Shukla, P.K, Sinha, M, Dey, S, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2012-08-04 | Release date: | 2012-08-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Design of peptide inhibitors of phospholipase A2: crystal Structure of phospholipase A2 complexed with a designed tetrapeptide Val - Ilu- Ala - Lys at 2.7 A resolution To be Published
|
|
4GLD
| Crystal Structure of the complex of type II phospholipase A2 with a designed peptide inhibitor Phe - Leu - Ala - Tyr - Lys at 1.69 A resolution | Descriptor: | ACETATE ION, FLAYK, Phospholipase A2 VRV-PL-VIIIa, ... | Authors: | Shukla, P.K, Sinha, M, Dey, S, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2012-08-14 | Release date: | 2012-08-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Crystal Structure of the complex of type II phospholipase A2 with a designed peptide inhibitor Phe - Leu - Ala - Tyr - Lys at 1.69 A resolution To be Published
|
|
4HG9
| Crystal structure of AhV_bPA, a basic PLA2 from Agkistrodon halys pallas venom | Descriptor: | Basic phospholipase A2 B, CALCIUM ION, CITRIC ACID, ... | Authors: | Zeng, F, Niu, L, Li, X, Teng, M. | Deposit date: | 2012-10-07 | Release date: | 2012-10-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of AhV_bPA, a basic PLA2 from Agkistrodon halys pallas venom TO BE PUBLISHED
|
|
4H0S
| |
4HMB
| Crystal Structure of the complex of group II phospholipase A2 with a 3-{3-[(Dimethylamino)methyl]-1H-indol-7-yl}propan-1-ol at 2.21 A Resolution | Descriptor: | 3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL, Phospholipase A2 VRV-PL-VIIIa | Authors: | Shukla, P.K, Haridas, M, Chandra, D.N, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2012-10-18 | Release date: | 2012-11-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Crystal Structure of the complex of group II phospholipase A2 with a 3-{3-[(Dimethylamino)methyl]-1H-indol-7-yl}propan-1-ol at 2.21 A Resolution To be Published
|
|
4FGA
| Design of peptide inhibitors of group II phospholipase A2: Crystal structure of the complex of phospholipsae A2 with a designed tripeptide, Ala- Tyr- Lys at 2.3 A resolution | Descriptor: | AYK, Phospholipase A2 VRV-PL-VIIIa | Authors: | Shukla, P.K, Sinha, M, Dey, S, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2012-06-04 | Release date: | 2012-06-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Design of peptide inhibitors of group II phospholipase A2: Crystal structure of the complex of phospholipsae A2 with a designed tripeptide, Ala- Tyr- Lys at 2.3 A resolution To be Published
|
|
1MH2
| Crystal Structure of a Zinc Containing Dimer of Phospholipase A2 from the Venom of Indian Cobra (Naja Naja Sagittifera) | Descriptor: | ACETIC ACID, PHOSPHOLIPASE A2, ZINC ION | Authors: | Jabeen, T, Varma, A.K, Paramasivam, M, Singh, N, Singh, R.K, Sharma, S, Srinivasan, A, Singh, T.P. | Deposit date: | 2002-08-19 | Release date: | 2003-05-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of a Zinc Containing Dimer of Phospholipase A2 from the Venom of Indian cobra (Naja Naja Saggittifera) To be Published
|
|
1MH7
| |
1MC2
| monomeric LYS-49 phospholipase A2 homologue purified from AG | Descriptor: | Acutohaemonlysin, ISOPROPYL ALCOHOL | Authors: | Liu, Q, Huang, Q.Q, Zhang, R.G, Weeks, C.M, Jelsch, C, Teng, M.K, Niu, L.W. | Deposit date: | 2002-08-05 | Release date: | 2002-08-21 | Last modified: | 2018-02-14 | Method: | X-RAY DIFFRACTION (0.85 Å) | Cite: | The crystal structure of a novel, inactive, lysine 49 PLA2 from Agkistrodon acutus venom: an ultrahigh resolution, AB initio structure determination J.Biol.Chem., 278, 2003
|
|
1MH8
| Crystal Structure of a Phopholipase A2 Monomer with Isoleucine at Second Position | Descriptor: | PHOSPHOLIPASE A2 | Authors: | Jabeen, T, Jasti, J, Singh, N, Singh, R.K, Sharma, S, Singh, T.P. | Deposit date: | 2002-08-19 | Release date: | 2003-06-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystal Structure of a Phospholipase A2 Monomer with Isoleucine at Second Position To be Published
|
|
1MKS
| |
1MF4
| Structure-based design of potent and selective inhibitors of phospholipase A2: Crystal structure of the complex formed between phosholipase A2 from Naja Naja sagittifera and a designed peptide inhibitor at 1.9 A resolution | Descriptor: | CALCIUM ION, Phospholipase A2, VAL-ALA-PHE-ARG-SER | Authors: | Singh, R.K, Vikram, P, Paramsivam, M, Jabeen, T, Sharma, S, Makker, J, Dey, S, Kaur, P, Srinivasan, A, Singh, T.P. | Deposit date: | 2002-08-09 | Release date: | 2003-09-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Design of specific peptide inhibitors for group I phospholipase A2: structure of a complex formed between phospholipase A2 from Naja naja sagittifera (group I) and a designed peptide inhibitor Val-Ala-Phe-Arg-Ser (VAFRS) at 1.9 A resolution reveals unique features Biochemistry, 42, 2003
|
|
1N28
| Crystal structure of the H48Q mutant of human group IIA phospholipase A2 | Descriptor: | CALCIUM ION, Phospholipase A2, membrane associated | Authors: | Edwards, S.H, Thompson, D, Baker, S.F, Wood, S.P, Wilton, D.C. | Deposit date: | 2002-10-22 | Release date: | 2003-10-28 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The crystal structure of the H48Q active site mutant of human group IIA secreted phospholipase A2 at 1.5 A resolution provides an insight into the catalytic mechanism Biochemistry, 41, 2002
|
|
1N29
| Crystal structure of the N1A mutant of human group IIA phospholipase A2 | Descriptor: | CALCIUM ION, Phospholipase A2, membrane associated | Authors: | Edwards, S.H, Thompson, D, Baker, S.F, Wood, S.P, Wilton, D.C. | Deposit date: | 2002-10-22 | Release date: | 2003-10-28 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The crystal structure of the H48Q active site mutant of human group IIA secreted phospholipase A2 at 1.5 A resolution provides an insight into the catalytic mechanism Biochemistry, 41, 2002
|
|
5TFV
| |
5VFM
| |
5VFJ
| |
5VFH
| |