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5WZS

Crystal structure of human secreted phospholipase A2 group IIE with Compound 8

Summary for 5WZS
Entry DOI10.2210/pdb5wzs/pdb
Related5WZM 5WZO 5WZT 5WZU 5WZV 5WZW
DescriptorGroup IIE secretory phospholipase A2, 2-[2-methyl-1-(naphthalen-1-ylmethyl)-3-oxamoyl-indol-4-yl]oxyethanoic acid, CALCIUM ION, ... (7 entities in total)
Functional Keywordsphospholipase a2, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological sourceHomo sapiens (Human)
Cellular locationSecreted: Q9NZK7
Total number of polymer chains1
Total formula weight14648.32
Authors
Hou, S.,Xu, J.,Xu, T.,Liu, J. (deposition date: 2017-01-18, release date: 2018-01-24, Last modification date: 2023-11-22)
Primary citationHou, S.,Xu, T.,Xu, J.,Qu, L.,Xu, Y.,Chen, L.,Liu, J.
Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE
Sci Rep, 7:10815-10815, 2017
Cited by
PubMed: 28883454
DOI: 10.1038/s41598-017-11219-8
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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