4FGA

Design of peptide inhibitors of group II phospholipase A2: Crystal structure of the complex of phospholipsae A2 with a designed tripeptide, Ala- Tyr- Lys at 2.3 A resolution

Summary for 4FGA

• Entry DOI: 10.2210/pdb4fga/pdb
• Related: 4EIX
• Descriptor: Phospholipase A2 VRV-PL-VIIIa, AYK (3 entities in total)
• Functional Keywords: pla2, anti-inflammatory, anti-coagulant, peptide-inhibitor, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Daboia russellii pulchella (Russell's viper); More
• Total number of polymer chains: 2
• Total formula weight: 14011.21

Authors

Shukla, P.K.,Sinha, M.,Dey, S.,Kaur, P.,Sharma, S.,Singh, T.P. (deposition date: 2012-06-04, release date: 2012-06-27, Last modification date: 2023-11-08)

• Primary citation: Shukla, P.K.,Sinha, M.,Dey, S.,Kaur, P.,Sharma, S.,Singh, T.P.; Design of peptide inhibitors of group II phospholipase A2: Crystal structure of the complex of phospholipsae A2 with a designed tripeptide, Ala- Tyr- Lys at 2.3 A resolution; To be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)