5Y5E

Crystal structure of phospholipase A2 with inhibitor

Summary for 5Y5E

• Entry DOI: 10.2210/pdb5y5e/pdb
• Descriptor: Group IIE secretory phospholipase A2, GLYCEROL, 2-[2-methyl-3-oxamoyl-1-[[2-(trifluoromethyl)phenyl]methyl]indol-4-yl]oxyethanoic acid, ... (8 entities in total)
• Functional Keywords: mutant, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 14978.21

Authors

Hou, S.,Xu, J.,Xu, T.,Liu, J. (deposition date: 2017-08-08, release date: 2018-06-20, Last modification date: 2023-11-22)

• Primary citation: Hou, S.,Xu, T.,Xu, J.,Qu, L.,Xu, Y.,Chen, L.,Liu, J.; Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2group IIE; Sci Rep, 7:10815-10815, 2017; PubMed: 28883454; DOI: 10.1038/s41598-017-11219-8

Experimental method

X-RAY DIFFRACTION (1.8 Å)