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6PHC
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BU of 6phc by Molmil
Pfs25 in complex with the human transmission blocking antibody 2544
Descriptor: 25 kDa ookinete surface antigen, 2544 Antibody Fab, Heavy Chain, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHB
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BU of 6phb by Molmil
Pfs25 in complex with the human transmission blocking antibody 2530
Descriptor: 1,2-ETHANEDIOL, 25 kDa ookinete surface antigen, 2530 Antibody Fab, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6BA5
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BU of 6ba5 by Molmil
Potent and Selective Antitumor Activity of a T-Cell Engaging Bispecific Antibody Targeting a Membrane-Proximal Epitope of ROR1
Descriptor: Inactive tyrosine-protein kinase transmembrane receptor ROR1, Variable domain Heavy chain, antibody R11, ...
Authors:Park, H, Rader, C.
Deposit date:2017-10-12
Release date:2018-06-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4QT5
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BU of 4qt5 by Molmil
Crystal Structure of 3BD10: A Monoclonal Antibody against the TSH Receptor
Descriptor: 3BD10 mouse monoclonal antibody, heavy chain, light chain
Authors:Hubbard, P.A, Chen, C.R, McLachlan, S.M, Rapoport, B, Murali, R.
Deposit date:2014-07-07
Release date:2015-04-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a TSH receptor monoclonal antibody: insight into Graves' disease pathogenesis.
Mol.Endocrinol., 29, 2015
6CWK
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BU of 6cwk by Molmil
Anti-RTA VHH antibody
Descriptor: 1,2-ETHANEDIOL, Anti-Ricin antibody, CHLORIDE ION, ...
Authors:Rudolph, M.J, Mantis, N.
Deposit date:2018-03-30
Release date:2019-01-16
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.256 Å)
Cite:Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.
Protein Eng. Des. Sel., 31, 2018
1FH5
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BU of 1fh5 by Molmil
CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF THE MONOCLONAL ANTIBODY MAK33
Descriptor: MONOCLONAL ANTIBODY MAK33
Authors:Augustine, J.G, de la Calle, A, Knarr, G, Buchner, J, Frederick, C.A.
Deposit date:2000-07-31
Release date:2000-09-13
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of the fab fragment of the monoclonal antibody MAK33. Implications for folding and interaction with the chaperone bip.
J.Biol.Chem., 276, 2001
6P62
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BU of 6p62 by Molmil
HIV Env BG505 NFL TD+ in complex with antibody E70 fragment antigen binding
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env BG505 NFL TD+, ...
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2019-05-31
Release date:2019-11-20
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability.
Immunity, 51, 2019
6B0E
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BU of 6b0e by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1260
Descriptor: 1260 antibody, heavy chain, light chain, ...
Authors:Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-14
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B0G
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BU of 6b0g by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245
Descriptor: 1245 Antibody, Heavy Chain, Light Chain, ...
Authors:McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-14
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6CWG
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BU of 6cwg by Molmil
Ricin catalytic subunit bound go A9 VHH antibody
Descriptor: CHLORIDE ION, Ricin, VHH antibody
Authors:Rudolph, M.J, Mantis, N.
Deposit date:2018-03-30
Release date:2019-01-16
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.
Protein Eng. Des. Sel., 31, 2018
6AZZ
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BU of 6azz by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1190
Descriptor: 1190 antibody, heavy chain, light chain, ...
Authors:Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-13
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
2BFV
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BU of 2bfv by Molmil
MONOCLONAL ANTIBODY FRAGMENT FV4155 FROM E. COLI
Descriptor: ESTRIOL 3-(B-D-GLUCURONIDE), FV4155
Authors:Trinh, C.H, Phillips, S.E.V.
Deposit date:1997-05-27
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Antibody fragment Fv4155 bound to two closely related steroid hormones: the structural basis of fine specificity.
Structure, 5, 1997
5EOR
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BU of 5eor by Molmil
Structure of the murine antibody Fab 8E3 bound to the vaccinia virus A27 peptide 101-110
Descriptor: Protein A27, SODIUM ION, anti vaccinia virus A27 antibody 8E3 heavy chain, ...
Authors:Matho, M.H, Zajonc, D.M.
Deposit date:2015-11-10
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox.
J.Virol., 90, 2016
4GQ9
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BU of 4gq9 by Molmil
Chikungunya virus neutralizing antibody 9.8B Fab fragment
Descriptor: Chikungunya virus neutralizing antibody 9.8B Fab fragment heavy chain, Chikungunya virus neutralizing antibody 9.8B Fab fragment light chain
Authors:Sun, S, Rossmann, M.G.
Deposit date:2012-08-22
Release date:2013-07-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.995 Å)
Cite:Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.
Elife, 2, 2013
6M58
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BU of 6m58 by Molmil
Crystal structure of a complex between human serum albumin and the antibody Fab SL335
Descriptor: Heavy chain of the SL335 antibody fab, Light chain of the SL335 antibody Fab, Serum albumin
Authors:Cho, S.Y, Yoon, S.I.
Deposit date:2020-03-10
Release date:2020-04-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural basis of serum albumin recognition by SL335, an antibody Fab extending the serum half-life of protein therapeutics.
Biochem.Biophys.Res.Commun., 526, 2020
6B0A
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BU of 6b0a by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1269
Descriptor: 1269 antibody, heavy chain, light chain, ...
Authors:Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-14
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B08
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BU of 6b08 by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1276
Descriptor: 1276 antibody, heavy chain, light chain, ...
Authors:Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-14
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B0H
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BU of 6b0h by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1262
Descriptor: 1,2-ETHANEDIOL, 1262 antibody, heavy chain, ...
Authors:McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-14
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6MUI
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BU of 6mui by Molmil
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-42 antibody
Descriptor: E1, E2, EEEV-42 antibody heavy chain, ...
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-23
Release date:2018-12-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6CK8
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BU of 6ck8 by Molmil
Crystal structure of anti-influenza single-domain llama antibody SD38
Descriptor: GLYCEROL, Llama antibody SD38, PENTAETHYLENE GLYCOL, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2018-02-27
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
5XQW
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BU of 5xqw by Molmil
Catalytic antibody 7B9
Descriptor: Fab fragment of catalytic antibody 7B9, heavy chain, light chain, ...
Authors:Ito, N, Fujii, I, Tsumuraya, T.
Deposit date:2017-06-07
Release date:2018-04-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of the broad substrate tolerance of the antibody 7B9-catalyzed hydrolysis of p-nitrobenzyl esters.
Bioorg. Med. Chem., 26, 2018
8R9Y
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BU of 8r9y by Molmil
S1B domain of the PDCoV spike glycoprotein in complex with the 67B12 and 42H3 antibody Fab fragments
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 42H3 antibody heavy chain, ...
Authors:Debski-Antoniak, O, Hurdiss, D.L.
Deposit date:2023-11-30
Release date:2024-06-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein.
Nat Commun, 15, 2024
4QCI
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BU of 4qci by Molmil
PDGF-B blocking antibody bound to PDGF-BB
Descriptor: Platelet-derived growth factor subunit B, anti-PDGF-BB antibody - Light Chain, anti-PDGF-BB antibody - Heavy chain
Authors:Kuai, J, Mosyak, L, Tam, M, LaVallie, E, Pullen, N, Carven, G.
Deposit date:2014-05-12
Release date:2015-03-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)-B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity Needed for PDGF-BB To Bind PDGF Receptor-beta.
Biochemistry, 54, 2015
6DF0
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BU of 6df0 by Molmil
anti-phosphotyrosine antibody 4G10-4D5 Fab complexed with sulfate
Descriptor: 4G10-4D5 Antibody Light chain, 4G10-4D5 Antibody heavy chain, SULFATE ION
Authors:Mou, K, Leung, K, Wells, J.A.
Deposit date:2018-05-13
Release date:2018-11-28
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Engineering Improved Antiphosphotyrosine Antibodies Based on an Immunoconvergent Binding Motif.
J. Am. Chem. Soc., 140, 2018
6DEZ
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BU of 6dez by Molmil
Anti-phosphotyrosine antibody PY20-4D5 Fab complexed with sulfate
Descriptor: Anti-phosphotyrosine antibody PY20-4D5 heavy chain, Anti-phosphotyrosine antibody PY20-4D5 light chain, SULFATE ION
Authors:Mou, K, Leung, K, Wells, J.A.
Deposit date:2018-05-13
Release date:2018-11-28
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Engineering Improved Antiphosphotyrosine Antibodies Based on an Immunoconvergent Binding Motif.
J. Am. Chem. Soc., 140, 2018

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數據於2024-07-24公開中

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