6AZZ

Crystal structure of Pfs25 in complex with the transmission blocking antibody 1190

Summary for 6AZZ

• Entry DOI: 10.2210/pdb6azz/pdb
• Descriptor: 1190 antibody, heavy chain, 1190 antibody, light chain, Pfs25, ... (6 entities in total)
• Functional Keywords: transmission blocking vaccine, malaria, antibody, egf-like domain, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 135067.67

Authors

Scally, S.W.,McLeod, B.,Bosch, A.,King, C.R.,Julien, J.P. (deposition date: 2017-09-13, release date: 2017-11-08, Last modification date: 2023-10-04)

• Primary citation: Scally, S.W.,McLeod, B.,Bosch, A.,Miura, K.,Liang, Q.,Carroll, S.,Reponen, S.,Nguyen, N.,Giladi, E.,Ramisch, S.,Yusibov, V.,Bradley, A.,Lemiale, F.,Schief, W.R.,Emerling, D.,Kellam, P.,King, C.R.,Julien, J.P.; Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.; Nat Commun, 8:1568-1568, 2017; PubMed: 29146922; DOI: 10.1038/s41467-017-01924-3

Experimental method

X-RAY DIFFRACTION (2.4 Å)