6B0G
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245
Summary for 6B0G
Entry DOI | 10.2210/pdb6b0g/pdb |
Related | 6AZZ 6B08 6B0A 6B0E |
Descriptor | 1245 Antibody, Light Chain, 1245 Antibody, Heavy Chain, 25 kDa ookinete surface antigen, ... (5 entities in total) |
Functional Keywords | transmission blocking vaccine, malaria, antibody, egf-like domain, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane ; Lipid-anchor, GPI-anchor : P13829 |
Total number of polymer chains | 3 |
Total formula weight | 69096.74 |
Authors | McLeod, B.,Scally, S.W.,Bosch, A.,King, C.R.,Julien, J.P. (deposition date: 2017-09-14, release date: 2017-11-08, Last modification date: 2023-10-04) |
Primary citation | Scally, S.W.,McLeod, B.,Bosch, A.,Miura, K.,Liang, Q.,Carroll, S.,Reponen, S.,Nguyen, N.,Giladi, E.,Ramisch, S.,Yusibov, V.,Bradley, A.,Lemiale, F.,Schief, W.R.,Emerling, D.,Kellam, P.,King, C.R.,Julien, J.P. Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8:1568-1568, 2017 Cited by PubMed: 29146922DOI: 10.1038/s41467-017-01924-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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