6B0G

Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0009986	cellular_component	cell surface
E	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue GOL D 301

Chain	Residue
D	VAL89
D	GLN105
D	GLY106
D	THR108
D	HOH439
D	HOH498

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site_id	AC2
Number of Residues	7
Details	binding site for residue GOL D 302

Chain	Residue
D	ASP95
D	HOH401
D	HOH438
D	HOH457
C	PRO96
D	TRP50
D	LYS58

---

site_id	AC3
Number of Residues	12
Details	binding site for residue GOL D 303

Chain	Residue
C	GLN160
C	GLU161
C	SER162
C	SER176
C	SER177
C	THR178
D	PHE171
D	PRO172
D	SER182
D	LEU183
D	SER184
D	HOH408

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL E 201

Chain	Residue
E	VAL92
E	GLN125
E	LYS127
E	HOH316

---

site_id	AC5
Number of Residues	3
Details	binding site for residue GOL E 202

Chain	Residue
E	LYS142
E	GLU145
E	HOH311

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
C	TYR192-HIS198
D	TYR199-HIS205

---

site_id	PS01186
Number of Residues	14
Details	EGF_2 EGF-like domain signature 2. CkCnlGYdmvnnv..C

Chain	Residue	Details
E	CYS71-CYS84
E	CYS156-CYS171

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	29
Details	Domain: {"description":"EGF-like 1; truncated"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	44
Details	Domain: {"description":"EGF-like 3"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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