6B0G
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | 1245 Antibody, Light Chain | polymer | 219 | 24081.8 | 1 | Homo sapiens (Human) | ||
| 2 | B (D) | 1245 Antibody, Heavy Chain | polymer | 228 | 24450.4 | 1 | Homo sapiens (Human) | ||
| 3 | C (E) | 25 kDa ookinete surface antigen | polymer | 183 | 20104.2 | 1 | UniProt (P13829) Pfam (PF06247) | Plasmodium falciparum | Pfs25 |
| 4 | D, E, F, G, H (D, E) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | I, J, K (C, D, E) | water | water | 18.0 | 546 | Chemie (HOH) |
Sequence modifications
E: 1 - 172 (UniProt: P13829)
| PDB | External Database | Details |
|---|---|---|
| Thr -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gln 91 | Asn 112 | conflict |
| Gln 144 | Asn 165 | conflict |
| Gln 166 | Asn 187 | conflict |
| Gly 173 | - | expression tag |
| Thr 174 | - | expression tag |
| Lys 175 | - | expression tag |
| His 176 | - | expression tag |
| His 177 | - | expression tag |
| His 178 | - | expression tag |
| His 179 | - | expression tag |
| His 180 | - | expression tag |
| His 181 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 68636.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 460.5 | |
| All* | Total formula weight | 69096.7 |
