1SHR
 
 | | Crystal structure of ferrocyanide bound human hemoglobin A2 at 1.88A resolution | | Descriptor: | CYANIDE ION, FE (III) ION, Hemoglobin alpha chain, ... | | Authors: | Sen, U, Dasgupta, J, Choudhury, D, Datta, P, Chakrabarti, A, Chakrabarty, S.B, Chakrabarty, A, Dattagupta, J.K. | | Deposit date: | 2004-02-26 | | Release date: | 2004-10-26 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Crystal structures of HbA2 and HbE and modeling of hemoglobin delta4: interpretation of the thermal stability and the antisickling effect of HbA2 and identification of the ferrocyanide binding site in Hb
Biochemistry, 43, 2004
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1SI4
 | | Crystal structure of Human hemoglobin A2 (in R2 state) at 2.2 A resolution | | Descriptor: | CYANIDE ION, Hemoglobin alpha chain, Hemoglobin delta chain, ... | | Authors: | Sen, U, Dasgupta, J, Choudhury, D, Datta, P, Chakrabarti, A, Chakrabarty, S.B, Chakrabarty, A, Dattagupta, J.K. | | Deposit date: | 2004-02-27 | | Release date: | 2004-10-26 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of HbA2 and HbE and modeling of hemoglobin delta4: interpretation of the thermal stability and the antisickling effect of HbA2 and identification of the ferrocyanide binding site in Hb.
Biochemistry, 43, 2004
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8DW8
 | | Host-guest structure of BLMA2 partially bound to 5'-ATTAGTTATAACTAAT-3' | | Descriptor: | BLEOMYCIN A2, DNA (5'-D(*AP*TP*TP*AP*GP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*CP*TP*AP*AP*T)-3'), ... | | Authors: | Georgiadis, M.M. | | Deposit date: | 2022-07-31 | | Release date: | 2023-01-11 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.58 Å) | | Cite: | Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A 2 and B 2 bound to duplex 5'-TAGTT sites.
Bioorg.Med.Chem., 77, 2023
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8DU2
 | | HnRNPA2 D290V LCD PM1 | | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1 | | Authors: | Eisenberg, D.S, Lu, J, Ge, P, Boyer, D.R. | | Deposit date: | 2022-07-26 | | Release date: | 2023-08-02 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation.
J.Biol.Chem., 300, 2023
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8DUW
 | | HnRNPA2 D290V LCD PM2 | | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1 | | Authors: | Eisenberg, D.S, Lu, J, Ge, P, Boyer, D.R. | | Deposit date: | 2022-07-27 | | Release date: | 2023-08-02 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation.
J.Biol.Chem., 300, 2023
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8EC7
 | | HnRNPA2 D290V LCD PM3 | | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1 | | Authors: | Eisenberg, D.S, Lu, J, Ge, P, Boyer, D.R. | | Deposit date: | 2022-09-01 | | Release date: | 2023-09-06 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation.
J.Biol.Chem., 300, 2023
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9GLA
 | | Crystal structure of a CDK2-based CDK7 mimic with inhibitor SY5609 | | Descriptor: | 7-dimethylphosphoryl-3-[2-[[(3~{S})-6,6-dimethylpiperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1~{H}-indole-6-carbonitrile, Cyclin-A2, Cyclin-dependent kinase 2, ... | | Authors: | Skerlova, J, Krejcirikova, V, Rezacova, P. | | Deposit date: | 2024-08-27 | | Release date: | 2025-04-02 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | CDK2-based CDK7 mimic as a tool for structural analysis: Biochemical validation and crystal structure with SY5609.
Int.J.Biol.Macromol., 294, 2025
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8ESB
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8ESA
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8ES9
 | | CryoEM structure of PN45428 TCR-CD3 in complex with HLA-A2 MAGEA4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | | Authors: | Saotome, K, Franklin, M.C. | | Deposit date: | 2022-10-13 | | Release date: | 2023-05-03 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM.
Nat Commun, 14, 2023
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8ES8
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6PTE
 | | Crystal Structure of ILNAMITKI peptide bound to HLA-A2 | | Descriptor: | Beta-2-microglobulin, GLYCEROL, HAUS augmin-like complex subunit 3, ... | | Authors: | Smith, A.R, Arbuiso, A, Keller, G.L.J, Baker, B.M. | | Deposit date: | 2019-07-15 | | Release date: | 2019-09-04 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.901 Å) | | Cite: | Structure Based Prediction of Neoantigen Immunogenicity.
Front Immunol, 10, 2019
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6PTB
 | | Crystal Structure of ILNAMIAKI peptide bound to HLA-A2 | | Descriptor: | Beta-2-microglobulin, GLYCEROL, HAUS augmin-like complex subunit 3, ... | | Authors: | Keller, G.L.J, Arbuiso, A, Baker, B.M. | | Deposit date: | 2019-07-15 | | Release date: | 2019-09-04 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure Based Prediction of Neoantigen Immunogenicity.
Front Immunol, 10, 2019
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6RPA
 | | Crystal structure of the T-cell receptor NYE_S2 bound to HLA A2*01-SLLMWITQV | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | | Authors: | Coles, C.H, Mulvaney, R, Malla, S, Lloyd, A, Smith, K, Chester, F, Knox, A, Stacey, A.R, Dukes, J, Baston, E, Griffin, S, Vuidepot, A, Jakobsen, B.K, Harper, S. | | Deposit date: | 2019-05-14 | | Release date: | 2020-01-15 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex.
J Immunol., 204, 2020
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6RP9
 | | Crystal structure of the T-cell receptor NYE_S3 bound to HLA A2*01-SLLMWITQV | | Descriptor: | Beta-2-microglobulin, Cancer/testis antigen 1, HLA class I histocompatibility antigen, ... | | Authors: | Coles, C.H, Mulvaney, R, Malla, S, Lloyd, A, Smith, K, Chester, F, Knox, A, Stacey, A.R, Dukes, J, Baston, E, Griffin, S, Vuidepot, A, Jakobsen, B.K, Harper, S. | | Deposit date: | 2019-05-14 | | Release date: | 2020-01-15 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3.12 Å) | | Cite: | TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex.
J Immunol., 204, 2020
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1AQD
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1K3M
 | | NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALA, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES | | Descriptor: | INSULIN | | Authors: | Xu, B, Hua, Q.-X, Nakagawa, S.H, Jia, W, Chu, Y.-C, Katsoyannis, P.G, Weiss, M.A. | | Deposit date: | 2001-10-03 | | Release date: | 2001-10-17 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | A cavity-forming mutation in insulin induces segmental unfolding of a surrounding alpha-helix.
Protein Sci., 11, 2002
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8JMX
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6UZ1
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4GZA
 | | Complex of mouse Plexin A2 - Semaphorin 3A - Neuropilin-1 | | Descriptor: | CALCIUM ION, Neuropilin-1, Plexin-A2, ... | | Authors: | Janssen, B.J.C, Malinauskas, T, Siebold, C, Jones, E.Y. | | Deposit date: | 2012-09-06 | | Release date: | 2012-10-17 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (7 Å) | | Cite: | Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex.
Nat.Struct.Mol.Biol., 19, 2012
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8XDA
 | | Cryo-EM structure of urea bound human urea transporter A2. | | Descriptor: | UREA, Urea transporter 2 | | Authors: | Huang, S, Liu, L, Sun, J, Zhizheng, H. | | Deposit date: | 2023-12-10 | | Release date: | 2024-12-04 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into the mechanisms of urea permeation and distinct inhibition modes of urea transporters.
Nat Commun, 15, 2024
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8XD9
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8XDD
 | | Cryo-EM structure of human urea transporter A2. | | Descriptor: | 1-(3-methoxyphenyl)methanamine, 8-hydroxyquinoline-2-carboxylic acid, Urea transporter 2 | | Authors: | Huang, S, Liu, L, Sun, J. | | Deposit date: | 2023-12-10 | | Release date: | 2024-12-04 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into the mechanisms of urea permeation and distinct inhibition modes of urea transporters.
Nat Commun, 15, 2024
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5E00
 | | Structure of HLA-A2 P130 | | Descriptor: | Beta-2-microglobulin, GLY-VAL-TRP-ILE-ARG-THR-PRO-PRO-ALA, HLA class I histocompatibility antigen, ... | | Authors: | Zhang, Y, Wu, Y, Qi, J, Liu, J, Gao, G.F, Meng, S. | | Deposit date: | 2015-09-26 | | Release date: | 2017-01-18 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018
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3EBB
 | | PLAP/P97 complex | | Descriptor: | MAGNESIUM ION, PHOSPHOLIPASE A2-ACTIVATING PROTEIN, TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE (TER ATP | | Authors: | Walker, J.R, Qiu, L, Akutsu, M, Slessarev, Y, Amaya, M.F, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-08-27 | | Release date: | 2009-02-24 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure and function of the PLAA/Ufd3-p97/Cdc48 complex.
J.Biol.Chem., 285, 2010
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