1AQD

HLA-DR1 (DRA, DRB1 0101) HUMAN CLASS II HISTOCOMPATIBILITY PROTEIN (EXTRACELLULAR DOMAIN) COMPLEXED WITH ENDOGENOUS PEPTIDE

Summary for 1AQD

DescriptorHLA-DR1 CLASS II HISTOCOMPATIBILITY PROTEIN, HLA-A2, ... (4 entities in total)
Functional Keywordscomplex (mhc protein-antigen), histocompatibility antigen, complex (mhc protein-antigen) complex, complex (mhc protein/antigen)
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Single-pass type I membrane protein P01903 P04229
Membrane; Single-pass type I membrane protein P01892
Total number of polymer chains12
Total molecular weight188146.67
Authors
Murthy, V.L.,Stern, L.J. (deposition date: 1997-07-28, release date: 1998-01-28, Last modification date: 2011-07-13)
Primary citation
Murthy, V.L.,Stern, L.J.
The class II MHC protein HLA-DR1 in complex with an endogenous peptide: implications for the structural basis of the specificity of peptide binding.
Structure, 5:1385-1396, 1997
PubMed: 9351812 (PDB entries with the same primary citation)
DOI: 10.1016/S0969-2126(97)00288-8
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.45 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.264140.3%4.7%2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution