PDB: 222415 resultsInfo pagesStatus searchChemie searchBIRD

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4EI9	Crystal structure of Bacillus cereus TubZ, GTP-form Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Plasmid replication protein RepX Authors: Hayashi, I, Hoshino, S. Deposit date: 2012-04-05 Release date: 2012-08-15 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Filament formation of the FtsZ/tubulin-like protein TubZ from the Bacillus cereus pXO1 plasmid. J.Biol.Chem., 287, 2012
4EIK	Crystal Structure of the Human Fyn SH3 domain in complex with the synthetic peptide VSL12 Descriptor: SODIUM ION, Tyrosine-protein kinase Fyn, VSL12 peptide Authors: Camara-Artigas, A. Deposit date: 2012-04-05 Release date: 2013-04-10 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystallization of and selenomethionine phasing strategy for a SETMAR-DNA complex. Acta Crystallogr F Struct Biol Commun, 72, 2016
4K9D	X-ray crystal structure of a Glyceraldehyde 3-phosphate dehydrogenase from Brugia malayi bound to the co-factor NAD Descriptor: 1,2-ETHANEDIOL, Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-04-19 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: X-ray crystal structure of a Glyceraldehyde 3-phosphate dehydrogenase from Brugia malayi bound to the co-factor NAD TO BE PUBLISHED
4ER6	Crystal structure of human DOT1L in complex with inhibitor SGC0946 Descriptor: 5-bromo-7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, BROMIDE ION, Histone-lysine N-methyltransferase, ... Authors: Wernimont, A.K, Tempel, W, Yu, W, Scopton, A, Li, Y, Nguyen, K.T, Vedadi, M, Bradner, J.E, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Brown, P.J, Structural Genomics Consortium (SGC) Deposit date: 2012-04-19 Release date: 2012-05-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun, 3, 2012
4K8K	Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 1-(4-methoxyphenyl)-1-cyclopropane and 2-aminoperimidine Descriptor: 1-(4-methoxyphenyl)cyclopropanecarboxylic acid, 1H-perimidin-2-amine, ADENOSINE, ... Authors: Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) Deposit date: 2013-04-18 Release date: 2013-05-01 Last modified: 2013-05-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 1-(4-methoxyphenyl)-1-cyclopropane and 2-aminoperimidine To be Published
4EWR	X-ray structure of WDR5-SETd1a Win motif peptide binary complex Descriptor: Histone-lysine N-methyltransferase SETD1A, WD repeat-containing protein 5 Authors: Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S. Deposit date: 2012-04-27 Release date: 2012-05-30 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.503 Å) Cite: Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases. J.Biol.Chem., 287, 2012
4EM8	The Structure of Ribose 5-phosphate Isomerase B from Anaplasma phagocytophilum Descriptor: Ribose 5-phosphate isomerase B Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-04-11 Release date: 2012-04-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: The Structure of Ribose 5-phosphate Isomerase B from Anaplasma phagocytophilum To be Published
4KMH	Crystal structure of Suppressor of Fused d20 Descriptor: Suppressor of fused homolog Authors: Zhang, Y, Qi, X, Zhang, Z, Wu, G. Deposit date: 2013-05-08 Release date: 2013-11-20 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.04 Å) Cite: Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci. Nat Commun, 4, 2013
4E51	Crystal structure of a histidyl-tRNA synthetase HisRS from Burkholderia thailandensis bound to histidine Descriptor: HISTIDINE, Histidine--tRNA ligase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-03-13 Release date: 2012-03-28 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms. Sci Rep, 7, 2017
4E5O	Crystal structure of mouse thymidylate synthase in complex with dUMP Descriptor: 1,4-BUTANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase Authors: Dowiercial, A, Jarmula, A, Rypniewski, W, Sokolowska, M, Fraczyk, T, Ciesla, J, Rode, W. Deposit date: 2012-03-14 Release date: 2012-04-18 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme Struct Chem, 2016
4EO9	Crystal structure of a phosphoglycerate mutase gpm1 from Mycobacterium leprae Descriptor: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, CHLORIDE ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-04-13 Release date: 2012-04-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4KMF	Crystal structure of Zalpha domain from Carassius auratus PKZ in complex with Z-DNA Descriptor: DNA (5'-D(*TP*CP*GP*CP*GP*CP*G)-3'), Interferon-inducible and double-stranded-dependent eIF-2kinase, MANGANESE (II) ION Authors: Kim, D, Kim, K.K. Deposit date: 2013-05-08 Release date: 2013-07-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Distinct Z-DNA binding mode of a PKR-like protein kinase containing a Z-DNA binding domain (PKZ). Nucleic Acids Res., 42, 2014
4KNJ	Crystal structure of human carbonic anhydrase isozyme II with 2-Chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide, Carbonic anhydrase 2, ... Authors: Smirnov, A, Manakova, E, Grazulis, S. Deposit date: 2013-05-10 Release date: 2013-11-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Benzenesulfonamides with pyrimidine moiety as inhibitors of human carbonic anhydrases I, II, VI, VII, XII, and XIII Bioorg.Med.Chem., 21, 2013
4EE2	Crystal Structure of Anthrax Protective Antigen K446M Mutant to 1.91-A Resolution Descriptor: CALCIUM ION, Protective antigen Authors: Kintzer, A.F, Krantz, B.A. Deposit date: 2012-03-28 Release date: 2012-10-24 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Anthrax toxin protective antigen integrates poly-gamma-D-glutamate and pH signals to sense the optimal environment for channel formation. Proc.Natl.Acad.Sci.USA, 109, 2012
4EFI	Crystal Structure of 3-oxoacyl-(Acyl-carrier protein) Synthase from Burkholderia Xenovorans LB400 Descriptor: 3-oxoacyl-(Acyl-carrier protein) synthase, CHLORIDE ION, FORMIC ACID, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Craig, T.K, Abendroth, J, Staker, B, Stewart, L, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-03-29 Release date: 2012-04-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
4EG4	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor Chem 1289 Descriptor: 2-({3-[(3,5-dibromo-2-ethoxybenzyl)amino]propyl}amino)quinolin-4(1H)-one, DIMETHYL SULFOXIDE, GLYCEROL, ... Authors: Koh, C.Y, Kim, J.E, Shibata, S, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. Deposit date: 2012-03-30 Release date: 2012-09-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.151 Å) Cite: Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection. Structure, 20, 2012
4K5B	Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W Descriptor: Apoptosis regulator BCL-W, Bcl-2-like protein 2 Authors: Schilling, J, Schoeppe, J, Sauer, E, Plueckthun, A. Deposit date: 2013-04-14 Release date: 2014-04-16 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Co-Crystallization with Conformation-Specific Designed Ankyrin Repeat Proteins Explains the Conformational Flexibility of BCL-W J.Mol.Biol., 426, 2014
4KRM	Nanobody/VHH domain 7D12 in complex with domain III of the extracellular region of EGFR, pH 3.5 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ... Authors: Ferguson, K.M, Schmitz, K.R. Deposit date: 2013-05-16 Release date: 2013-08-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.655 Å) Cite: Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains. Structure, 21, 2013
4NH4	Structure of the binary complex of a zingiber officinale double bond reductase in complex with NADP Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Zingiber officinale double bond reductase Authors: Langlois D'Estaintot, B, Buratto, J, Granier, T, Gallois, B, Willis, M.A, Sang, Y, Flores-Sanchez, I.J, Gang, D.R. Deposit date: 2013-11-04 Release date: 2014-11-05 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of zingiber officinale double bond reductase To be Published
4NHO	Structure of the spliceosomal DEAD-box protein Prp28 Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, MERCURY (II) ION, ... Authors: Moehlmann, S, Neumann, P, Ficner, R. Deposit date: 2013-11-05 Release date: 2014-06-18 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28. Acta Crystallogr.,Sect.D, 70, 2014
4NI5	Crystal Structure of a Short Chain Dehydrogenase from Brucella suis Descriptor: MAGNESIUM ION, Oxidoreductase, short-chain dehydrogenase/reductase family protein Authors: Dranow, D.M, Abendroth, J, Edwards, T.E, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-11-05 Release date: 2013-11-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal Structure of a Short Chain Dehydrogenase from Brucella suis TO BE PUBLISHED
4EMB	Crystal structure of a phosphoglycerate mutase gpmA from Borrelia burgdorferi B31 Descriptor: 1,2-ETHANEDIOL, 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, CHLORIDE ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-04-11 Release date: 2012-04-25 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of a phosphoglycerate mutase gpmA from Borrelia burgdorferi B31 To be Published
4EMZ	HIV-1 Nef in complex with MHC-I cytoplasmic domain and Mu1 adaptin subunit of AP1 adaptor (second domain) Descriptor: AP-1 complex subunit mu-1, MHC-I, Protein Nef Authors: Jia, X, Xiong, Y. Deposit date: 2012-04-12 Release date: 2012-06-20 Last modified: 2012-07-25 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef. Nat.Struct.Mol.Biol., 19, 2012
4NH5	Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 14-mer siRNA having 5'-pUU and UU-3' ends (2.55 Angstrom resolution) Descriptor: 5'-R(P*UP*UP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer Authors: Tian, Y, Simanshu, D.K, Patel, D.J. Deposit date: 2013-11-04 Release date: 2014-03-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.55 Å) Cite: A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer. Mol.Cell, 53, 2014
4NIV	Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) trigonal form Descriptor: CALCIUM ION, Cationic trypsin, GLYCEROL Authors: Schoepfel, M, Parthier, C, Stubbs, M.T. Deposit date: 2013-11-08 Release date: 2014-02-19 Last modified: 2014-03-19 Method: X-RAY DIFFRACTION (1 Å) Cite: N-terminal protein modification by substrate-activated reverse proteolysis. Angew.Chem.Int.Ed.Engl., 53, 2014

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