2EA2
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![BU of 2ea2 by Molmil](/molmil-images/mine/2ea2) | h-MetAP2 complexed with A773812 | Descriptor: | 3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}-2-METHYLBENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2 | Authors: | Park, C.H. | Deposit date: | 2007-01-30 | Release date: | 2008-02-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids Bioorg.Med.Chem.Lett., 17, 2007
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4OZ5
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![BU of 4oz5 by Molmil](/molmil-images/mine/4oz5) | Bacillus subtilis HmoB | Descriptor: | Bacillus subtilis HmoB, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Choe, J, Park, S. | Deposit date: | 2014-02-13 | Release date: | 2015-02-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Bacillus subtilis HmoB To Be Published
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3S3R
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![BU of 3s3r by Molmil](/molmil-images/mine/3s3r) | Structure of cathepsin B1 from Schistosoma mansoni in complex with K11777 inhibitor | Descriptor: | Cathepsin B-like peptidase (C01 family), Nalpha-[(4-methylpiperazin-1-yl)carbonyl]-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-phenylalaninamide | Authors: | Rezacova, P, Jilkova, A, Brynda, J, Horn, M, Mares, M. | Deposit date: | 2011-05-18 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni. J.Biol.Chem., 286, 2011
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3T67
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![BU of 3t67 by Molmil](/molmil-images/mine/3t67) | |
4POO
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![BU of 4poo by Molmil](/molmil-images/mine/4poo) | The crystal structure of Bacillus subtilis YtqB in complex with SAM | Descriptor: | Putative RNA methylase, S-ADENOSYLMETHIONINE | Authors: | Park, S.C, Song, W.S, Yoon, S.I. | Deposit date: | 2014-02-26 | Release date: | 2014-04-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural analysis of a putative SAM-dependent methyltransferase, YtqB, from Bacillus subtilis Biochem.Biophys.Res.Commun., 446, 2014
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3SZ9
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![BU of 3sz9 by Molmil](/molmil-images/mine/3sz9) | |
3PR2
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![BU of 3pr2 by Molmil](/molmil-images/mine/3pr2) | Tryptophan synthase indoline quinonoid structure with F9 inhibitor in alpha site | Descriptor: | (Z)-N-[(1E)-1-carboxy-2-(2,3-dihydro-1H-indol-1-yl)ethylidene]{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1H)-ylidene}methanaminium, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, CESIUM ION, ... | Authors: | Lai, J, Niks, D, Wang, Y, Domratcheva, T, Barends, T.R.M, Schwarz, F, Olsen, R.A, Elliott, D.W, Fatmi, M.Q, Chang, C.A, Schlichting, I, Dunn, M.F, Mueller, L.J. | Deposit date: | 2010-11-29 | Release date: | 2011-02-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | X-ray and NMR Crystallography in an Enzyme Active Site: The Indoline Quinonoid Intermediate in Tryptophan Synthase. J.Am.Chem.Soc., 133, 2011
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1D2V
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![BU of 1d2v by Molmil](/molmil-images/mine/1d2v) | CRYSTAL STRUCTURE OF BROMIDE-BOUND HUMAN MYELOPEROXIDASE ISOFORM C AT PH 5.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, BROMIDE ION, ... | Authors: | Fiedler, T.J, Davey, C.A, Fenna, R.E. | Deposit date: | 1999-09-28 | Release date: | 2000-04-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | X-ray crystal structure and characterization of halide-binding sites of human myeloperoxidase at 1.8 A resolution. J.Biol.Chem., 275, 2000
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1D5L
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![BU of 1d5l by Molmil](/molmil-images/mine/1d5l) | CRYSTAL STRUCTURE OF CYANIDE-BOUND HUMAN MYELOPEROXIDASE ISOFORM C AT PH 5.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | Authors: | Fiedler, T.J, Davey, C.A, Fenna, R.E. | Deposit date: | 1999-10-07 | Release date: | 2001-12-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution. Biochemistry, 40, 2001
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1CXP
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4PON
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![BU of 4pon by Molmil](/molmil-images/mine/4pon) | The crystal structure of a putative SAM-dependent methyltransferase, YtqB, from Bacillus subtilis | Descriptor: | Putative RNA methylase | Authors: | Park, S.C, Song, W.S, Yoon, S.I. | Deposit date: | 2014-02-26 | Release date: | 2014-04-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural analysis of a putative SAM-dependent methyltransferase, YtqB, from Bacillus subtilis Biochem.Biophys.Res.Commun., 446, 2014
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2ZED
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![BU of 2zed by Molmil](/molmil-images/mine/2zed) | Crystal structure of the human glutaminyl cyclase mutant S160A at 1.7 angstrom resolution | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | Authors: | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | Deposit date: | 2007-12-12 | Release date: | 2008-04-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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2ZEH
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![BU of 2zeh by Molmil](/molmil-images/mine/2zeh) | Crystal structure of the human glutaminyl cyclase mutant E201Q at 1.8 angstrom resolution | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | Authors: | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | Deposit date: | 2007-12-12 | Release date: | 2008-04-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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1I84
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![BU of 1i84 by Molmil](/molmil-images/mine/1i84) | CRYO-EM STRUCTURE OF THE HEAVY MEROMYOSIN SUBFRAGMENT OF CHICKEN GIZZARD SMOOTH MUSCLE MYOSIN WITH REGULATORY LIGHT CHAIN IN THE DEPHOSPHORYLATED STATE. ONLY C ALPHAS PROVIDED FOR REGULATORY LIGHT CHAIN. ONLY BACKBONE ATOMS PROVIDED FOR S2 FRAGMENT. | Descriptor: | SMOOTH MUSCLE MYOSIN ESSENTIAL LIGHT CHAIN, SMOOTH MUSCLE MYOSIN HEAVY CHAIN, SMOOTH MUSCLE MYOSIN REGULATORY LIGHT CHAIN | Authors: | Wendt, T, Taylor, D, Trybus, K.M, Taylor, K. | Deposit date: | 2001-03-12 | Release date: | 2001-03-28 | Last modified: | 2022-12-21 | Method: | ELECTRON CRYSTALLOGRAPHY (20 Å) | Cite: | Three-dimensional image reconstruction of dephosphorylated smooth muscle heavy meromyosin reveals asymmetry in the interaction between myosin heads and placement of subfragment 2. Proc.Natl.Acad.Sci.USA, 98, 2001
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7Q6J
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![BU of 7q6j by Molmil](/molmil-images/mine/7q6j) | Crystal structure of the human GDAP1 CMT2 mutant-H123R | Descriptor: | DI(HYDROXYETHYL)ETHER, Ganglioside-induced differentiation-associated protein 1 | Authors: | Sutinen, A, Kursula, P. | Deposit date: | 2021-11-08 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insights into Charcot-Marie-Tooth disease-linked mutations in human GDAP1. Febs Open Bio, 12, 2022
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2ZEO
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![BU of 2zeo by Molmil](/molmil-images/mine/2zeo) | Crystal structure of the human glutaminyl cyclase mutant D305E at 1.66 angstrom resolution | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | Authors: | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | Deposit date: | 2007-12-13 | Release date: | 2008-04-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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2ZEF
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![BU of 2zef by Molmil](/molmil-images/mine/2zef) | Crystal structure of the human glutaminyl cyclase mutant E201D at 1.67 angstrom resolution | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | Authors: | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | Deposit date: | 2007-12-12 | Release date: | 2008-04-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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2ZEL
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![BU of 2zel by Molmil](/molmil-images/mine/2zel) | Crystal structure of the human glutaminyl cyclase mutant D248A at 1.97 angstrom resolution | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | Authors: | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | Deposit date: | 2007-12-13 | Release date: | 2008-04-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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6F3X
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![BU of 6f3x by Molmil](/molmil-images/mine/6f3x) | Backbone structure of Des-Arg10-Kallidin (DAKD) peptide in frozen DDM/CHS detergent micelle solution determined by DNP-enhanced MAS SSNMR | Descriptor: | Kininogen-1 | Authors: | Mao, J, Kuenze, G, Joedicke, L, Meiler, J, Michel, H, Glaubitz, C. | Deposit date: | 2017-11-29 | Release date: | 2018-01-10 | Last modified: | 2024-06-19 | Method: | SOLID-STATE NMR | Cite: | The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors. Nat. Chem. Biol., 14, 2018
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6ZMA
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![BU of 6zma by Molmil](/molmil-images/mine/6zma) | Structure of the tRNA-Monooxygenase enzyme MiaE frozen under 140 bar of krypton using the soak and freeze methodology | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | Authors: | Carpentier, P, Atta, M. | Deposit date: | 2020-07-02 | Release date: | 2020-09-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural, biochemical and functional analyses of tRNA-monooxygenase enzyme MiaE from Pseudomonas putida provide insights into tRNA/MiaE interaction. Nucleic Acids Res., 48, 2020
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7Q6K
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2ZEG
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![BU of 2zeg by Molmil](/molmil-images/mine/2zeg) | Crystal structure of the human glutaminyl cyclase mutant E201L at 2.08 angstrom resolution | Descriptor: | Glutaminyl-peptide cyclotransferase, IMIDAZOLE, SULFATE ION, ... | Authors: | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | Deposit date: | 2007-12-12 | Release date: | 2008-04-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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2ZEM
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![BU of 2zem by Molmil](/molmil-images/mine/2zem) | Crystal structure of the human glutaminyl cyclase mutant D248Q at 2.18 angstrom resolution | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | Authors: | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | Deposit date: | 2007-12-13 | Release date: | 2008-04-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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2ZEP
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![BU of 2zep by Molmil](/molmil-images/mine/2zep) | Crystal structure of the human glutaminyl cyclase mutant H319L at 2.1 angstrom resolution | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | Authors: | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | Deposit date: | 2007-12-13 | Release date: | 2008-04-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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2ZEE
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![BU of 2zee by Molmil](/molmil-images/mine/2zee) | Crystal structure of the human glutaminyl cyclase mutant S160G at 1.99 angstrom resolution | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | Authors: | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | Deposit date: | 2007-12-12 | Release date: | 2008-04-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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