7Q6K
Crystal structure of the human GDAP1 CMT2 mutant-R120W
Summary for 7Q6K
| Entry DOI | 10.2210/pdb7q6k/pdb |
| Related | 7AIA 7ALM 7Q6J |
| Descriptor | Ganglioside-induced differentiation-associated protein 1 (1 entity in total) |
| Functional Keywords | charcot-marie-tooth, cmt2, mutation, mitochondria, signaling protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 32803.45 |
| Authors | Sutinen, A.,Kursula, P. (deposition date: 2021-11-08, release date: 2022-06-08, Last modification date: 2024-01-31) |
| Primary citation | Sutinen, A.,Nguyen, G.T.T.,Raasakka, A.,Muruganandam, G.,Loris, R.,Ylikallio, E.,Tyynismaa, H.,Bartesaghi, L.,Ruskamo, S.,Kursula, P. Structural insights into Charcot-Marie-Tooth disease-linked mutations in human GDAP1. Febs Open Bio, 12:1306-1324, 2022 Cited by PubMed: 35509130DOI: 10.1002/2211-5463.13422 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.41 Å) |
Structure validation
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