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1KHW
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BU of 1khw by Molmil
Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Mn2+
Descriptor: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
Authors:Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N.
Deposit date:2001-12-01
Release date:2002-01-16
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase.
J.Biol.Chem., 277, 2002
1ONV
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BU of 1onv by Molmil
NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNAP II CTD Phosphatase FCP1
Descriptor: Transcription initiation factor IIF, alpha subunit, serine phosphatase FCP1a
Authors:Nguyen, B.D, Abbott, K.L, Potempa, K, Kobor, M.S, Archambault, J, Greenblatt, J, Legault, P, Omichinski, J.G.
Deposit date:2003-03-02
Release date:2003-05-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1
Proc.Natl.Acad.Sci.USA, 100, 2003
3CJ2
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BU of 3cj2 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Kissinger, c.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
1UVK
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BU of 1uvk by Molmil
The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 dead-end complex
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M.
Deposit date:2004-01-21
Release date:2004-02-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
1ARO
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BU of 1aro by Molmil
T7 RNA POLYMERASE COMPLEXED WITH T7 LYSOZYME
Descriptor: MERCURY (II) ION, T7 LYSOZYME, T7 RNA POLYMERASE
Authors:Steitz, T, Jeruzalmi, D.
Deposit date:1997-08-08
Release date:1998-10-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of T7 RNA polymerase complexed to the transcriptional inhibitor T7 lysozyme.
EMBO J., 17, 1998
3CJ3
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BU of 3cj3 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Kissinger, c.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ4
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BU of 3cj4 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: 4-[(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)amino]-4-oxobutanoic acid, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Antonysamy, s.s.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
4QJF
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BU of 4qjf by Molmil
X-ray crystal structure of Thermocuccus kodakarensis RNA polymerase Rpp4/Rpo7 (RpoF/RpoE) complex
Descriptor: DNA-directed RNA polymerase, subunit E', subunit F
Authors:Murakami, K.S.
Deposit date:2014-06-03
Release date:2014-10-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.312 Å)
Cite:Crystal structure of euryarchaeal RNA polymerase and insight into the evolution of RNA polymerase II structure
Nat.Commun., 2014
6IRZ
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BU of 6irz by Molmil
Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA
Descriptor: 1,2-ETHANEDIOL, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, PDX1 C-terminal-inhibiting factor 1, ...
Authors:Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O.
Deposit date:2018-11-15
Release date:2018-12-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase.
Science, 363, 2019
5D98
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BU of 5d98 by Molmil
Influenza C Virus RNA-dependent RNA Polymerase - Space group P43212
Descriptor: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Hengrung, N, El Omari, K, Serna Martin, I, Vreede, F.T, Cusack, S, Rambo, R.P, Vonrhein, C, Bricogne, G, Stuart, D.I, Grimes, J.M, Fodor, E.
Deposit date:2015-08-18
Release date:2015-10-21
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
Nature, 527, 2015
1EF4
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BU of 1ef4 by Molmil
SOLUTION STRUCTURE OF THE ESSENTIAL RNA POLYMERASE SUBUNIT RPB10 FROM METHANOBACTERIUM THERMOAUTOTROPHICUM
Descriptor: DNA-DIRECTED RNA POLYMERASE, ZINC ION
Authors:Mackereth, C.D, Arrowsmith, C.H, Edwards, A.M, Mcintosh, L.P, Northeast Structural Genomics Consortium (NESG)
Deposit date:2000-02-07
Release date:2000-06-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Zinc-bundle structure of the essential RNA polymerase subunit RPB10 from Methanobacterium thermoautotrophicum.
Proc.Natl.Acad.Sci.USA, 97, 2000
4NC7
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BU of 4nc7 by Molmil
N-terminal domain of delta-subunit of RNA polymerase complexed with I3C and nickel ions
Descriptor: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, DNA-directed RNA polymerase subunit delta, NICKEL (II) ION
Authors:Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M.
Deposit date:2013-10-24
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase.
J.Struct.Biol., 187, 2014
4PN0
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BU of 4pn0 by Molmil
Structure of S. pombe Pct1 RNA triphosphatase
Descriptor: mRNA-capping enzyme subunit beta
Authors:Lima, C.D, Doamekpor, S.K.
Deposit date:2014-05-22
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Fission yeast RNA triphosphatase reads an Spt5 CTD code.
Rna, 21, 2015
4PN1
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BU of 4pn1 by Molmil
Structure of S. pombe Pct1 RNA triphosphatase in complex with the Spt5 CTD
Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, Synthetic peptide, ...
Authors:Lima, C.D, Doamekpor, S.K.
Deposit date:2014-05-22
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Fission yeast RNA triphosphatase reads an Spt5 CTD code.
Rna, 21, 2015
2R7Z
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BU of 2r7z by Molmil
Cisplatin lesion containing RNA polymerase II elongation complex
Descriptor: 5'-D(*CP*AP*AP*GP*TP*AP*G)-3', 5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3', 5'-R(*UP*UP*UP*GP*AP*GP*GP*AP*GP*G)-3', ...
Authors:Damsma, G.E, Alt, A, Brueckner, F, Carell, T, Cramer, P.
Deposit date:2007-09-10
Release date:2007-11-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Mechanism of transcriptional stalling at cisplatin-damaged DNA.
Nat.Struct.Mol.Biol., 14, 2007
8BYQ
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BU of 8byq by Molmil
RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-14
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
8BZ1
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BU of 8bz1 by Molmil
RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-14
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
8BVW
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BU of 8bvw by Molmil
RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-20
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
7XSZ
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BU of 7xsz by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC115)
Descriptor: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
Authors:Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2022-05-15
Release date:2022-09-07
Last modified:2022-10-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
7XT7
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BU of 7xt7 by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC49B)
Descriptor: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
Authors:Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2022-05-16
Release date:2022-10-12
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
7XTD
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BU of 7xtd by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC58oct)
Descriptor: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
Authors:Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2022-05-16
Release date:2022-09-07
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
7XTI
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BU of 7xti by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC58hex)
Descriptor: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
Authors:Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2022-05-17
Release date:2022-10-12
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
7XSX
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BU of 7xsx by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC49)
Descriptor: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
Authors:Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2022-05-15
Release date:2022-09-07
Last modified:2022-10-12
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
7XSE
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BU of 7xse by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC42)
Descriptor: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
Authors:Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2022-05-13
Release date:2022-09-07
Last modified:2022-10-12
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
7XN7
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BU of 7xn7 by Molmil
RNA polymerase II elongation complex containing Spt4/5, Elf1, Spt6, Spn1 and Paf1C
Descriptor: Chromatin elongation factor SPT5, Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, ...
Authors:Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2022-04-28
Release date:2022-09-07
Last modified:2022-10-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022

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數據於2024-06-12公開中

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