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5MDU
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BU of 5mdu by Molmil
Structure of the RNA recognition motif (RRM) of Seb1 from S. pombe.
Descriptor: CHLORIDE ION, GLYCEROL, Rpb7-binding protein seb1, ...
Authors:Wittmann, S, Renner, M, El Omari, K, Adams, O, Vasiljeva, L, Grimes, J.
Deposit date:2016-11-13
Release date:2017-04-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA.
Nat Commun, 8, 2017
6IZY
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BU of 6izy by Molmil
The RNA-dependent RNA polymerase domain of dengue 2 NS5
Descriptor: COBALT (II) ION, Genome polyprotein, ZINC ION
Authors:Shimizu, H, Sekine, S.
Deposit date:2018-12-20
Release date:2019-12-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase.
Plos Negl Trop Dis, 13, 2019
5N5Y
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BU of 5n5y by Molmil
Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation III)
Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
Authors:Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P.
Deposit date:2017-02-14
Release date:2017-04-05
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Structural Basis of RNA Polymerase I Transcription Initiation.
Cell, 169, 2017
5N5Z
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BU of 5n5z by Molmil
Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation II)
Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
Authors:Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P.
Deposit date:2017-02-14
Release date:2017-04-05
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Structural Basis of RNA Polymerase I Transcription Initiation.
Cell, 169, 2017
5N60
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BU of 5n60 by Molmil
Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation I)
Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
Authors:Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P.
Deposit date:2017-02-14
Release date:2017-04-05
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Structural Basis of RNA Polymerase I Transcription Initiation.
Cell, 169, 2017
7VBA
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BU of 7vba by Molmil
Structure of the pre state human RNA Polymerase I Elongation Complex
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (5'-D(P*A*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*GP*C)-3'), DNA (5'-D(P*GP*CP*CP*AP*GP*AP*GP*AP*CP*AP*GP*CP*GP*AP*GP*TP*CP*AP*GP*CP*AP*A)-3'), ...
Authors:Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y.
Deposit date:2021-08-31
Release date:2022-02-16
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structure of the human RNA polymerase I elongation complex.
Cell Discov, 7, 2021
7VBC
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BU of 7vbc by Molmil
Back track state of human RNA Polymerase I Elongation Complex
Descriptor: DNA (5'-D(*GP*TP*AP*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*G)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*AP*GP*CP*GP*TP*GP*TP*CP*AP*GP*CP*AP*AP*TP*A)-3'), DNA-directed RNA polymerase I subunit RPA1, ...
Authors:Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y.
Deposit date:2021-08-31
Release date:2022-02-16
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structure of the human RNA polymerase I elongation complex.
Cell Discov, 7, 2021
7VBB
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BU of 7vbb by Molmil
Structure of the post state human RNA Polymerase I Elongation Complex
Descriptor: DNA (25-MER), DNA (5'-D(*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*GP*CP*GP*A)-3'), DNA-directed RNA polymerase I subunit RPA1, ...
Authors:Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y.
Deposit date:2021-08-31
Release date:2022-03-02
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Structure of the human RNA polymerase I elongation complex.
Cell Discov, 7, 2021
1EF4
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BU of 1ef4 by Molmil
SOLUTION STRUCTURE OF THE ESSENTIAL RNA POLYMERASE SUBUNIT RPB10 FROM METHANOBACTERIUM THERMOAUTOTROPHICUM
Descriptor: DNA-DIRECTED RNA POLYMERASE, ZINC ION
Authors:Mackereth, C.D, Arrowsmith, C.H, Edwards, A.M, Mcintosh, L.P, Northeast Structural Genomics Consortium (NESG)
Deposit date:2000-02-07
Release date:2000-06-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Zinc-bundle structure of the essential RNA polymerase subunit RPB10 from Methanobacterium thermoautotrophicum.
Proc.Natl.Acad.Sci.USA, 97, 2000
5FJ8
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BU of 5fj8 by Molmil
Cryo-EM structure of yeast RNA polymerase III elongation complex at 3. 9 A
Descriptor: DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1, DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10, DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2, ...
Authors:Hoffmann, N.A, Jakobi, A.J, Moreno-Morcillo, M, Glatt, S, Kosinski, J, Hagen, W.J, Sachse, C, Muller, C.W.
Deposit date:2015-10-06
Release date:2015-11-25
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular Structures of Unbound and Transcribing RNA Polymerase III.
Nature, 528, 2015
8A43
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BU of 8a43 by Molmil
Human RNA polymerase I
Descriptor: DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA2, ...
Authors:Daiss, J.L, Pilsl, M, Straub, K, Bleckmann, A, Hoecherl, M, Heiss, F.B, Abascal-Palacios, G, Ramsay, E, Tluckova, K, Mars, J.C, Fuertges, T, Bruckmann, A, Rudack, T, Bernecky, C, Lamour, V, Panov, K, Vannini, A, Moss, T, Engel, C.
Deposit date:2022-06-10
Release date:2022-08-31
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (4.09 Å)
Cite:The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans.
Life Sci Alliance, 5, 2022
6TPS
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BU of 6tps by Molmil
early intermediate RNA Polymerase I Pre-initiation complex - eiPIC
Descriptor: DNA foreign, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, ...
Authors:Pilsl, M, Engel, C.
Deposit date:2019-12-14
Release date:2020-03-18
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural basis of RNA polymerase I pre-initiation complex formation and promoter melting.
Nat Commun, 11, 2020
7DTI
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BU of 7dti by Molmil
Solution structure of the complex between RNA polymerase subunit RPB6 and TFIIH p62 PH domain
Descriptor: DNA-directed RNA polymerases I, II, and III subunit RPABC2, ...
Authors:Okuda, M, Nishimura, Y.
Deposit date:2021-01-05
Release date:2022-08-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Three human RNA polymerases interact with TFIIH via a common RPB6 subunit.
Nucleic Acids Res., 50, 2022
7DTH
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BU of 7dth by Molmil
Solution structure of RPB6, common subunit of RNA polymerases I, II, and III
Descriptor: DNA-directed RNA polymerases I, II, and III subunit RPABC2
Authors:Okuda, M, Nishimura, Y.
Deposit date:2021-01-05
Release date:2022-01-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Three human RNA polymerases interact with TFIIH via a common RPB6 subunit.
Nucleic Acids Res., 50, 2022
6RFL
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BU of 6rfl by Molmil
Structure of the complete Vaccinia DNA-dependent RNA polymerase complex
Descriptor: DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ...
Authors:Grimm, C, Hillen, S.H, Bedenk, K, Bartuli, J, Neyer, S, Zhang, Q, Huettenhofer, A, Erlacher, M, Dienemann, C, Schlosser, A, Urlaub, H, Boettcher, B, Szalay, A.A, Cramer, P, Fischer, U.
Deposit date:2019-04-15
Release date:2019-12-11
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes.
Cell, 179, 2019
6TUT
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BU of 6tut by Molmil
Cryo-EM structure of the RNA Polymerase III-Maf1 complex
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Vorlaender, M.K, Hagen, W.J.H, Mueller, C.W.
Deposit date:2020-01-08
Release date:2020-02-19
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Structural basis for RNA polymerase III transcription repression by Maf1.
Nat.Struct.Mol.Biol., 27, 2020
8Q3B
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BU of 8q3b by Molmil
The closed state of the ASFV apo-RNA polymerase
Descriptor: DNA-directed RNA polymerase RPB1 homolog, DNA-directed RNA polymerase RPB10 homolog, DNA-directed RNA polymerase RPB2 homolog, ...
Authors:Pilotto, S, Sykora, M, Cackett, G, Werner, F.
Deposit date:2023-08-03
Release date:2024-02-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Structure of the recombinant RNA polymerase from African Swine Fever Virus.
Nat Commun, 15, 2024
8Q3K
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BU of 8q3k by Molmil
The open state of the ASFV apo-RNA polymerase
Descriptor: DNA-directed RNA polymerase RPB1 homolog, DNA-directed RNA polymerase RPB10 homolog, DNA-directed RNA polymerase RPB2 homolog, ...
Authors:Pilotto, S, Sykora, M, Cackett, G, Werner, F.
Deposit date:2023-08-04
Release date:2024-02-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Structure of the recombinant RNA polymerase from African Swine Fever Virus.
Nat Commun, 15, 2024
6KF9
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BU of 6kf9 by Molmil
Cryo-EM structure of Thermococcus kodakarensis RNA polymerase
Descriptor: DNA (27-MER), DNA (5'-D(P*TP*CP*GP*GP*TP*AP*AP*TP*CP*AP*CP*GP*CP*TP*CP*C)-3'), DNA-directed RNA polymerase subunit, ...
Authors:Jun, S.-H, Hyun, J, Jeong, H, Cha, J.S, Kim, H, Bartlett, M.S, Cho, H.-S, Murakami, K.S.
Deposit date:2019-07-07
Release date:2020-07-01
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
Nat Commun, 11, 2020
6KF4
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BU of 6kf4 by Molmil
Cryo-EM structure of Thermococcus kodakarensis RNA polymerase
Descriptor: DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit A'', DNA-directed RNA polymerase subunit D, ...
Authors:Jun, S.-H, Hyun, J, Jeong, H, Cha, J.S, Kim, H, Bartlett, M.S, Cho, H.-S, Murakami, K.S.
Deposit date:2019-07-06
Release date:2020-07-01
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.97 Å)
Cite:Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
Nat Commun, 11, 2020
7UM0
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BU of 7um0 by Molmil
Structure of the phage AR9 non-virion RNA polymerase holoenzyme in complex with two DNA oligonucleotides containing the AR9 P077 promoter as determined by cryo-EM
Descriptor: DNA (5'-D(P*GP*UP*U)-3'), DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, ...
Authors:Leiman, P.G, Fraser, A, Sokolova, M.L.
Deposit date:2022-04-05
Release date:2022-07-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase.
Nat Commun, 13, 2022
7UM1
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BU of 7um1 by Molmil
Structure of bacteriophage AR9 non-virion RNAP polymerase holoenzyme determined by cryo-EM
Descriptor: DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, DNA-directed RNA polymerase beta' subunit, ...
Authors:Leiman, P.G, Fraser, A, Sokolova, M.L.
Deposit date:2022-04-05
Release date:2022-07-06
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase.
Nat Commun, 13, 2022
7S01
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BU of 7s01 by Molmil
X-ray structure of the phage AR9 non-virion RNA polymerase holoenzyme in complex with a forked oligonucleotide containing the P077 promoter
Descriptor: DNA-directed RNA polymerase, DNA-directed RNA polymerase beta subunit, DNA-directed RNA polymerase beta' subunit, ...
Authors:Leiman, P.G, Sokolova, M.L, Gordeeva, J, Fraser, A, Severinov, K.V.
Deposit date:2021-08-28
Release date:2022-07-06
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase.
Nat Commun, 13, 2022
4RY5
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BU of 4ry5 by Molmil
C-terminal mutant (W550N) of HCV/J4 RNA polymerase
Descriptor: HCV J4 RNA polymerase (NS5B), MANGANESE (II) ION, URIDINE 5'-TRIPHOSPHATE
Authors:Jaeger, J, Cherry, A, Dennis, C.
Deposit date:2014-12-13
Release date:2014-12-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Hydrophobic and Charged Residues in the C-Terminal Arm of Hepatitis C Virus RNA-Dependent RNA Polymerase Regulate Initiation and Elongation.
J.Virol., 89, 2015
7AST
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BU of 7ast by Molmil
Apo Human RNA Polymerase III
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Ramsay, E.P, Abascal-Palacios, G, Daiss, J.L, King, H, Gouge, J, Pilsl, M, Beuron, F, Morris, E, Gunkel, P, Engel, C, Vannini, A.
Deposit date:2020-10-28
Release date:2020-12-23
Last modified:2020-12-30
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of human RNA polymerase III.
Nat Commun, 11, 2020

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數據於2024-06-26公開中

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