6HLR
Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP (core focused)
Summary for 6HLR
Entry DOI | 10.2210/pdb6hlr/pdb |
EMDB information | 0238 0239 0240 |
Descriptor | DNA-directed RNA polymerase I subunit RPA190, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerases I and III subunit RPAC2, ... (18 entities in total) |
Functional Keywords | transcription, polymerase, nucleotide, elongation |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
Total number of polymer chains | 15 |
Total formula weight | 547362.27 |
Authors | Tafur, L.,Sadian, Y.,Weis, F.,Muller, C.W. (deposition date: 2018-09-11, release date: 2019-04-03, Last modification date: 2024-05-15) |
Primary citation | Tafur, L.,Sadian, Y.,Hanske, J.,Wetzel, R.,Weis, F.,Muller, C.W. The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8:-, 2019 Cited by PubMed: 30913026DOI: 10.7554/eLife.43204 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.18 Å) |
Structure validation
Download full validation report