6HLR

Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP (core focused)

Summary for 6HLR

Entry DOI	10.2210/pdb6hlr/pdb
EMDB information	0238 0239 0240
Descriptor	DNA-directed RNA polymerase I subunit RPA190, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerases I and III subunit RPAC2, ... (18 entities in total)
Functional Keywords	transcription, polymerase, nucleotide, elongation
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More
Total number of polymer chains	15
Total formula weight	547362.27
Authors	Tafur, L.,Sadian, Y.,Weis, F.,Muller, C.W. (deposition date: 2018-09-11, release date: 2019-04-03, Last modification date: 2024-05-15)
Primary citation	Tafur, L.,Sadian, Y.,Hanske, J.,Wetzel, R.,Weis, F.,Muller, C.W. The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8:-, 2019 Cited by PubMed: 30913026 DOI: 10.7554/eLife.43204 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.18 Å)

Structure validation