6DRD

RNA Pol II(G)

Summary for 6DRD

EMDB information7997 7998
DescriptorDNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... (14 entities in total)
Functional Keywordsrna pol ii(g), gdown1, transcription repression, molecular mechanism, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains13
Total molecular weight523566.62
Authors
Yu, X.,Jishage, M.,Shi, Y.,Ganesan, S.,Sali, A.,Chait, B.T.,Asturias, F.,Roeder, R.G. (deposition date: 2018-06-11, release date: 2019-06-12)
Primary citation
Jishage, M.,Yu, X.,Shi, Y.,Ganesan, S.J.,Chen, W.Y.,Sali, A.,Chait, B.T.,Asturias, F.J.,Roeder, R.G.
Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1.
Nat. Struct. Mol. Biol., 25:859-867, 2018
PubMed: 30190596 (PDB entries with the same primary citation)
DOI: 10.1038/s41594-018-0118-5
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers7 0.1% 0.6%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures