6DRD

RNA Pol II(G)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA-directed RNA polymerase II subunit RPB1	polymer	1970	217450.1	1	UniProt (P24928) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) In PDB	Homo sapiens (Human)	RNA polymerase II subunit B1,DNA-directed RNA polymerase II subunit A,DNA-directed RNA polymerase III largest subunit,RNA-directed RNA polymerase II subunit RPB1
2	B	DNA-directed RNA polymerase II subunit RPB2	polymer	1174	134071.5	1	UniProt (P30876) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) In PDB	Homo sapiens (Human)	DNA-directed RNA polymerase II 140 kDa polypeptide,DNA-directed RNA polymerase II subunit B,RNA polymerase II subunit 2,RNA polymerase II subunit B2
3	C	DNA-directed RNA polymerase II subunit RPB3	polymer	275	31478.1	1	UniProt (P19387) Pfam (PF01193) Pfam (PF01000) In PDB	Homo sapiens (Human)	RNA polymerase II subunit B3,DNA-directed RNA polymerase II 33 kDa polypeptide,RPB33,DNA-directed RNA polymerase II subunit C,RPB31
4	D	DNA-directed RNA polymerase II subunit RPB4	polymer	142	16331.3	1	UniProt (O15514) Pfam (PF03874) In PDB	Homo sapiens (Human)	RNA polymerase II subunit B4,DNA-directed RNA polymerase II subunit D,RNA polymerase II 16 kDa subunit,RPB16
5	E	DNA-directed RNA polymerases I, II, and III subunit RPABC1	polymer	210	24659.3	1	UniProt (P19388) Pfam (PF03871) Pfam (PF01191) In PDB	Homo sapiens (Human)	RNA polymerases I,II,and III subunit ABC1,DNA-directed RNA polymerase II 23 kDa polypeptide,DNA-directed RNA polymerase II subunit E,RPB5 homolog,XAP4
6	F	DNA-directed RNA polymerases I, II, and III subunit RPABC2	polymer	127	14491.0	1	UniProt (P61218) Pfam (PF01192) In PDB	Homo sapiens (Human)	RNA polymerases I,II,and III subunit ABC2,DNA-directed RNA polymerase II subunit F,DNA-directed RNA polymerases I,and III 14.4 kDa polypeptide,RPABC14.4,RPB14.4,RPB6 homolog,RPC15
7	G	DNA-directed RNA polymerase II subunit RPB7	polymer	172	19314.3	1	UniProt (P62487) Pfam (PF03876) Pfam (PF00575) In PDB	Homo sapiens (Human)	RNA polymerase II subunit B7,DNA-directed RNA polymerase II subunit G,RNA polymerase II 19 kDa subunit,RPB19
8	H	DNA-directed RNA polymerases I, II, and III subunit RPABC3	polymer	150	17162.3	1	UniProt (P52434) Pfam (PF03870) In PDB	Homo sapiens (Human)	RNA polymerases I,II,and III subunit ABC3,DNA-directed RNA polymerase II subunit H,DNA-directed RNA polymerases I,and III 17.1 kDa polypeptide,RPB17,RPB8 homolog,hRPB8
9	I	DNA-directed RNA polymerase II subunit RPB9	polymer	125	14541.2	1	UniProt (P36954) Pfam (PF02150) Pfam (PF01096) In PDB	Homo sapiens (Human)	RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5
10	J	DNA-directed RNA polymerases I, II, and III subunit RPABC5	polymer	67	7655.1	1	UniProt (P62875) Pfam (PF01194) In PDB	Homo sapiens (Human)	RNA polymerases I,II,and III subunit ABC5,DNA-directed RNA polymerase III subunit L,RNA polymerase II 7.6 kDa subunit,RPB7.6,RPB10 homolog
11	K	DNA-directed RNA polymerase II subunit RPB11-a	polymer	117	13310.3	1	UniProt (P52435) Pfam (PF13656) Pfam (PF01193) In PDB	Homo sapiens (Human)	RPB11a,DNA-directed RNA polymerase II subunit J-1,RNA polymerase II 13.3 kDa subunit
12	L	DNA-directed RNA polymerases I, II, and III subunit RPABC4	polymer	58	7018.2	1	UniProt (P53803) Pfam (PF03604) In PDB	Homo sapiens (Human)	RNA polymerases I,II,and III subunit ABC4,ABC10-alpha,DNA-directed RNA polymerase II subunit K,RNA polymerase II 7.0 kDa subunit,RPB7.0,RPB10alpha
13	M	DNA-directed RNA polymerase II subunit GRINL1A	polymer	62	5756.9	1	UniProt (P0CAP2) In PDB	Homo sapiens (Human)	DNA-directed RNA polymerase II subunit M,Glutamate receptor-like protein 1A
14	C, I, J, L	ZINC ION	non-polymer		65.4	5	Chemie (ZN)

Sequence modifications

A: 1 - 1970 (UniProt: P24928)

PDB	External Database	Details
Thr 1835	Ala 1835	conflict

E: 1 - 210 (UniProt: P19388)

PDB	External Database	Details
Phe 44	Ser 44	conflict
Glu 132	Gln 132	conflict
Ser 157	Thr 157	conflict
Arg 186	Lys 186	conflict

M: 58 - 102 (PDB: 6DRD)
M: 300 - 316 (UniProt: P0CAP2)

Contents of the asymmetric unit

Polymers	Number of chains	13
	Total formula weight	523239.6
Non-Polymers*	Number of molecules	5
	Total formula weight	327.0
All*	Total formula weight	523566.6

*Water molecules are not included.