RNA Polymerase II form II in 150 mM Mn+2

Summary for 2NVY

Related1I50 2E2H 2E2I 2E2J 2NVQ 2NVS 2NVT 2NVX 2NVZ
DescriptorDNA-directed RNA polymerase II largest subunit, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 45 kDa polypeptide, ... (12 entities in total)
Functional Keywordstranscription, mrna, multiprotein complex, molecular machine, dna
Biological sourceSaccharomyces cerevisiae (baker's yeast)
Cellular locationNucleus P04050 P08518 P16370 P20434 P20436 P27999 P38902
Cytoplasm P20435
Nucleus, nucleolus P22139 P40422
Total number of polymer chains10
Total molecular weight470259.13
Wang, D.,Bushnell, D.A.,Westover, K.D.,Kaplan, C.D.,Kornberg, R.D. (deposition date: 2006-11-13, release date: 2006-12-26, Last modification date: 2011-07-13)
Primary citation
Wang, D.,Bushnell, D.A.,Westover, K.D.,Kaplan, C.D.,Kornberg, R.D.
Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127:941-954, 2006
PubMed: 17129781 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2006.11.023
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.28229 3.7% 9.4% 8.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-28