6EU2

Apo RNA Polymerase III - open conformation (oPOL3)

Summary for 6EU2

EMDB information3957
DescriptorDNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC2, DNA-directed RNA polymerases I and III subunit RPAC1, ... (19 entities in total)
Functional Keywordsrna pol iii, promoter opening, transcription
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Cellular locationNucleus  P04051 P22276 P47076 P20434 P35718 P20436 P36121 P25441 P32910 P17890
Nucleus, nucleolus  P07703 Q04307 P22139 P28000 P40422
Cytoplasm  P20435 P32349
Total number of polymer chains17
Total molecular weight694526.96
Authors
Abascal-Palacios, G.,Ramsay, E.P.,Beuron, F.,Morris, E.,Vannini, A. (deposition date: 2017-10-27, release date: 2018-01-17, Last modification date: 2018-01-31)
Primary citation
Abascal-Palacios, G.,Ramsay, E.P.,Beuron, F.,Morris, E.,Vannini, A.
Structural basis of RNA polymerase III transcription initiation.
Nature, 553:301-306, 2018
PubMed: 29345637 (PDB entries with the same primary citation)
DOI: 10.1038/nature25441
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers50.5%1.7%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures