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4DV4
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BU of 4dv4 by Molmil
Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A914G
Descriptor: 16S rRNA, MAGNESIUM ION, ZINC ION, ...
Authors:Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G.
Deposit date:2012-02-22
Release date:2013-02-27
Method:X-RAY DIFFRACTION (3.651 Å)
Cite:A structural basis for streptomycin resistance
To be Published
6AWD
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BU of 6awd by Molmil
Structure of 30S (S1 depleted) ribosomal subunit and RNA polymerase complex
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
Deposit date:2017-09-05
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
6AWB
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BU of 6awb by Molmil
Structure of 30S ribosomal subunit and RNA polymerase complex in non-rotated state
Descriptor: 16S rRNA, 30S ribosomal protein S1, 30S ribosomal protein S10, ...
Authors:Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
Deposit date:2017-09-05
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
6AWC
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BU of 6awc by Molmil
Structure of 30S ribosomal subunit and RNA polymerase complex in rotated state
Descriptor: 16S rRNA, 30S ribosomal protein S1, 30S ribosomal protein S10, ...
Authors:Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
Deposit date:2017-09-05
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
6AZ1
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BU of 6az1 by Molmil
Cryo-EM structure of the small subunit of Leishmania ribosome bound to paromomycin
Descriptor: E-site tRNA, LACK1, MAGNESIUM ION, ...
Authors:Shalev-Benami, M, Zhang, Y, Rozenberg, H, Matzov, D, Zimmerman, E, Bashan, A, Jaffe, C.L, Yonath, A, Skiniotis, G.
Deposit date:2017-09-09
Release date:2017-12-06
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.
Nat Commun, 8, 2017
6CAP
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BU of 6cap by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus in complex with Sisomicin
Descriptor: (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, ...
Authors:DeMirci, H.
Deposit date:2018-01-31
Release date:2018-07-25
Last modified:2020-10-21
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of 30S ribosomal subunit from Thermus thermophilus in complex with Sisomicin
To Be Published
6CAS
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BU of 6cas by Molmil
Serial Femtosecond X-ray Crystal Structure of 30S ribosomal subunit from Thermus thermophilus in complex with N1MS
Descriptor: 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:DeMirci, H.
Deposit date:2018-01-31
Release date:2018-07-25
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature.
Nucleic Acids Res., 46, 2018
6CAR
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BU of 6car by Molmil
Serial Femtosecond X-ray Crystal Structure of 30S ribosomal subunit from Thermus thermophilus in complex with Sisomicin
Descriptor: (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, ...
Authors:DeMirci, H.
Deposit date:2018-01-31
Release date:2018-07-25
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature.
Nucleic Acids Res., 46, 2018
6CFL
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BU of 6cfl by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with lysyl-CAM and bound to protein Y (YfiA) at 2.6A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
Authors:Tereshchenkov, A.G, Dobosz-Bartoszek, M, Osterman, I.A, Marks, J, Sergeeva, V.A, Kasatsky, P, Komarova, E.S, Stavrianidi, A.N, Rodin, I.A, Konevega, A.L, Sergiev, P.V, Sumbatyan, N.V, Mankin, A.S, Bogdanov, A.A, Polikanov, Y.S.
Deposit date:2018-02-15
Release date:2018-03-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Binding and Action of Amino Acid Analogs of Chloramphenicol upon the Bacterial Ribosome.
J. Mol. Biol., 430, 2018
6BOK
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BU of 6bok by Molmil
E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Svidritskiy, E, Korostelev, A.A.
Deposit date:2017-11-20
Release date:2018-05-23
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Conformational Control of Translation Termination on the 70S Ribosome.
Structure, 26, 2018
6BZ7
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BU of 6bz7 by Molmil
Thermus thermophilus 70S containing 16S G299A point mutation and near-cognate ASL Leucine in A site.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2017-12-22
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.68 Å)
Cite:Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
Nucleic Acids Res., 47, 2019
6C5L
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BU of 6c5l by Molmil
Conformation of methylated GGQ in the Peptidyl Transferase Center during translation termination (T. thermophilus)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Zeng, F, Jin, H.
Deposit date:2018-01-16
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Conformation of methylated GGQ in the Peptidyl Transferase Center during Translation Termination.
Sci Rep, 8, 2018
6CAE
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BU of 6cae by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with NOSO-95179 antibiotic and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Pantel, L, Florin, T, Dobosz-Bartoszek, M, Racine, E, Sarciaux, M, Serri, M, Houard, J, Campagne, J.M, Marcia de Figueiredo, R, Midrier, C, Gaudriault, S, Givaudan, A, Lanois, A, Forst, S, Aumelas, A, Cotteaux-Lautard, C, Bolla, J.M, Vingsbo Lundberg, C, Huseby, D, Hughes, D, Villain-Guillot, P, Mankin, A.S, Polikanov, Y.S, Gualtieri, M.
Deposit date:2018-01-30
Release date:2018-04-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Odilorhabdins, Antibacterial Agents that Cause Miscoding by Binding at a New Ribosomal Site.
Mol. Cell, 70, 2018
6BOH
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BU of 6boh by Molmil
Antibiotic blasticidin S and E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Svidritskiy, E, Korostelev, A.A.
Deposit date:2017-11-20
Release date:2018-05-23
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Conformational Control of Translation Termination on the 70S Ribosome.
Structure, 26, 2018
6BU8
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BU of 6bu8 by Molmil
70S ribosome with S1 domains 1 and 2 (Class 1)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ...
Authors:Loveland, A.B, Korostelev, A.A.
Deposit date:2017-12-08
Release date:2018-01-31
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural dynamics of protein S1 on the 70S ribosome visualized by ensemble cryo-EM.
Methods, 137, 2018
6CAQ
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BU of 6caq by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Descriptor: 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:DeMirci, H.
Deposit date:2018-01-31
Release date:2018-07-25
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
To Be Published
6BUW
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BU of 6buw by Molmil
Thermus thermophilus 70S complex containing 16S G299A ram mutation and empty A site.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2017-12-11
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
Nucleic Acids Res., 47, 2019
6BZ6
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BU of 6bz6 by Molmil
Thermus thermophilus 70S complex containing 16S G347U ram mutation and empty A site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2017-12-22
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
Nucleic Acids Res., 47, 2019
6C4I
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BU of 6c4i by Molmil
Conformation of methylated GGQ in the peptidyl transferase center during translation termination
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Zeng, F, Jin, H.
Deposit date:2018-01-12
Release date:2018-02-21
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Conformation of methylated GGQ in the Peptidyl Transferase Center during Translation Termination.
Sci Rep, 8, 2018
6CFJ
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BU of 6cfj by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with histidyl-CAM and bound to mRNA and A-, P-, and E-site tRNAs at 2.8A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Tereshchenkov, A.G, Dobosz-Bartoszek, M, Osterman, I.A, Marks, J, Sergeeva, V.A, Kasatsky, P, Komarova, E.S, Stavrianidi, A.N, Rodin, I.A, Konevega, A.L, Sergiev, P.V, Sumbatyan, N.V, Mankin, A.S, Bogdanov, A.A, Polikanov, Y.S.
Deposit date:2018-02-15
Release date:2018-03-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding and Action of Amino Acid Analogs of Chloramphenicol upon the Bacterial Ribosome.
J. Mol. Biol., 430, 2018
6CFK
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BU of 6cfk by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with D-histidyl-CAM and bound to protein Y (YfiA) at 2.7A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
Authors:Tereshchenkov, A.G, Dobosz-Bartoszek, M, Osterman, I.A, Marks, J, Sergeeva, V.A, Kasatsky, P, Komarova, E.S, Stavrianidi, A.N, Rodin, I.A, Konevega, A.L, Sergiev, P.V, Sumbatyan, N.V, Mankin, A.S, Bogdanov, A.A, Polikanov, Y.S.
Deposit date:2018-02-15
Release date:2018-03-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Binding and Action of Amino Acid Analogs of Chloramphenicol upon the Bacterial Ribosome.
J. Mol. Biol., 430, 2018
6B4V
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BU of 6b4v by Molmil
Antibiotic blasticidin S and E. coli release factor 1 bound to the 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Svidritskiy, E, Korostelev, A.A.
Deposit date:2017-09-27
Release date:2018-02-07
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Mechanism of Inhibition of Translation Termination by Blasticidin S.
J. Mol. Biol., 430, 2018
6BZ8
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BU of 6bz8 by Molmil
Thermus thermophilus 70S containing 16S G347U point mutation and near-cognate ASL Leucine in A site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2017-12-22
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.74 Å)
Cite:Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
Nucleic Acids Res., 47, 2019
6CAO
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BU of 6cao by Molmil
Structure of the ribosomal decoding complex at ambient temperature
Descriptor: 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:DeMirci, H.
Deposit date:2018-01-31
Release date:2018-07-25
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structure of the 30S ribosomal decoding complex at ambient temperature.
RNA, 24, 2018
6CZR
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BU of 6czr by Molmil
The structure of amicetin bound to the 70S ribosome
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
Authors:Eiler, D.R, Steitz, T.A, Looper, R.E, Serrano, C.M, Kannareddy, H.R, Koch, M.R, Barrows, L.R, Testa, C.A, Sebahar, P.R.
Deposit date:2018-04-09
Release date:2019-04-10
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Unifying the Aminohexopyranose- and Peptidyl-Nucleoside Antibiotics: Implications for Antibiotic Design
Angew.Chem.Int.Ed.Engl., 132, 2020

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數據於2024-06-12公開中

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