8OX1
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![BU of 8ox1 by Molmil](/molmil-images/mine/8ox1) | Structure of TRF1core in complex with telomeric nucleosome | Descriptor: | Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ... | Authors: | Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D. | Deposit date: | 2023-04-28 | Release date: | 2023-08-30 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis of telomeric nucleosome recognition by shelterin factor TRF1. Sci Adv, 9, 2023
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4FWF
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![BU of 4fwf by Molmil](/molmil-images/mine/4fwf) | Complex structure of LSD2/AOF1/KDM1b with H3K4 mimic | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.1, Lysine-specific histone demethylase 1B, ... | Authors: | Zhang, Q, Chen, Z. | Deposit date: | 2012-07-01 | Release date: | 2013-01-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b Cell Res., 23, 2013
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6V3N
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![BU of 6v3n by Molmil](/molmil-images/mine/6v3n) | Crystal structure of CDYL2 in complex with H3K27me3 | Descriptor: | ACE-GLN-LEU-ALA-THR-LYS-ALA-ALA-ARG-M3L-SER-ALA-PRO-ALA-THR-TYR-NH2, Chromodomain Y-like protein 2, UNKNOWN ATOM OR ION | Authors: | Qin, S, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC) | Deposit date: | 2019-11-26 | Release date: | 2020-04-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis for the Binding Selectivity of Human CDY Chromodomains. Cell Chem Biol, 27, 2020
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7LBK
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![BU of 7lbk by Molmil](/molmil-images/mine/7lbk) | |
3AZI
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![BU of 3azi by Molmil](/molmil-images/mine/3azi) | Crystal Structure of Human Nucleosome Core Particle Containing H4K31Q mutation | Descriptor: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | Authors: | Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. | Deposit date: | 2011-05-25 | Release date: | 2011-09-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
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5HJB
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![BU of 5hjb by Molmil](/molmil-images/mine/5hjb) | AF9 YEATS in complex with histone H3 Crotonylation at K9 | Descriptor: | Protein AF-9, peptide of Histone H3.1 | Authors: | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | Deposit date: | 2016-01-12 | Release date: | 2016-04-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain Mol.Cell, 62, 2016
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3U5O
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![BU of 3u5o by Molmil](/molmil-images/mine/3u5o) | |
3UIK
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![BU of 3uik by Molmil](/molmil-images/mine/3uik) | |
5FB0
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![BU of 5fb0 by Molmil](/molmil-images/mine/5fb0) | Crystal Structure of a PHD finger bound to histone H3 T3ph peptide | Descriptor: | Nuclear autoantigen Sp-100, Peptide from Histone H3, ZINC ION | Authors: | Li, H, Zhang, X. | Deposit date: | 2015-12-13 | Release date: | 2016-05-04 | Last modified: | 2016-06-22 | Method: | X-RAY DIFFRACTION (2.702 Å) | Cite: | Multifaceted Histone H3 Methylation and Phosphorylation Readout by the Plant Homeodomain Finger of Human Nuclear Antigen Sp100C J.Biol.Chem., 291, 2016
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5J9S
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![BU of 5j9s by Molmil](/molmil-images/mine/5j9s) | ENL YEATS in complex with histone H3 acetylation at K27 | Descriptor: | H3K27ac peptide from Histone H3.1, Protein ENL, SULFATE ION | Authors: | Li, Y, Li, H. | Deposit date: | 2016-04-11 | Release date: | 2017-03-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.702 Å) | Cite: | ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia Nature, 543, 2017
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8DK5
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![BU of 8dk5 by Molmil](/molmil-images/mine/8dk5) | Structure of 187bp LIN28b nucleosome with site 0 mutation | Descriptor: | DNA (187-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | Authors: | Lian, T, Guan, R, Bai, Y. | Deposit date: | 2022-07-02 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
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2UXN
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![BU of 2uxn by Molmil](/molmil-images/mine/2uxn) | Structural Basis of Histone Demethylation by LSD1 Revealed by Suicide Inactivation | Descriptor: | CHLORIDE ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Yang, M, Culhane, J.C, Szewczuk, L.M, Gocke, C.B, Brautigam, C.A, Tomchick, D.R, Machius, M, Cole, P.A, Yu, H. | Deposit date: | 2007-03-28 | Release date: | 2007-05-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structural Basis of Histone Demethylation by Lsd1 Revealed by Suicide Inactivation. Nat.Struct.Mol.Biol., 14, 2007
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5Z23
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![BU of 5z23 by Molmil](/molmil-images/mine/5z23) | Crystal structure of the nucleosome containing a chimeric histone H3/CENP-A CATD | Descriptor: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Arimura, Y, Tachiwana, H, Takagi, H. | Deposit date: | 2017-12-28 | Release date: | 2019-02-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism. Nat Commun, 10, 2019
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4A0N
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![BU of 4a0n by Molmil](/molmil-images/mine/4a0n) | Crystal structure of Survivin bound to the phosphorylated N-terminal tail of histone H3 | Descriptor: | BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5, HISTONE H3 PEPTIDE, ZINC ION | Authors: | Jeyaprakash, A.A, Basquin, C, Jayachandran, U, Conti, E. | Deposit date: | 2011-09-09 | Release date: | 2011-11-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.743 Å) | Cite: | Structural Basis for the Recognition of Phosphorylated Histone H3 by the Survivin Subunit of the Chromosomal Passenger Complex. Structure, 19, 2011
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6K1I
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![BU of 6k1i by Molmil](/molmil-images/mine/6k1i) | Human nucleosome core particle with gammaH2A.X variant | Descriptor: | CHLORIDE ION, DNA (147-MER), Histone H2AX, ... | Authors: | Sharma, D, De Falco, L, Davey, C.A. | Deposit date: | 2019-05-10 | Release date: | 2020-01-15 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome. Nat Commun, 10, 2019
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8EVG
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![BU of 8evg by Molmil](/molmil-images/mine/8evg) | |
7K5Y
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![BU of 7k5y by Molmil](/molmil-images/mine/7k5y) | |
8SPU
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![BU of 8spu by Molmil](/molmil-images/mine/8spu) | Structure of ESRRB nucleosome bound OCT4 at site c | Descriptor: | DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | Authors: | Lian, T, Guan, R, Bai, Y. | Deposit date: | 2023-05-03 | Release date: | 2023-06-28 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
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8OO7
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![BU of 8oo7 by Molmil](/molmil-images/mine/8oo7) | CryoEM Structure INO80core Hexasome complex composite model state1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, ... | Authors: | Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S. | Deposit date: | 2023-04-04 | Release date: | 2023-07-26 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling. Science, 381, 2023
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8GUJ
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![BU of 8guj by Molmil](/molmil-images/mine/8guj) | Bre1-nucleosome complex (Model II) | Descriptor: | DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ... | Authors: | Onishi, S, Sato, K, Hamada, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T. | Deposit date: | 2022-09-12 | Release date: | 2023-09-20 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structure of the human Bre1 complex bound to the nucleosome. Nat Commun, 15, 2024
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7E8D
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![BU of 7e8d by Molmil](/molmil-images/mine/7e8d) | NSD2 E1099K mutant bound to nucleosome | Descriptor: | DNA (185-MER), Histone H2A type 1, Histone H2B type 1-J, ... | Authors: | Sengoku, T, Sato, K, Nishizawa, T, Nureki, O, Ogata, K. | Deposit date: | 2021-03-01 | Release date: | 2021-11-10 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2. Nat Commun, 12, 2021
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6M4G
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![BU of 6m4g by Molmil](/molmil-images/mine/6m4g) | Structural mechanism of nucleosome dynamics governed by human histone variants H2A.B and H2A.Z.2.2 | Descriptor: | DNA (93-MER), Histone H2A-Bbd type 2/3, Histone H2B type 2-E, ... | Authors: | Zhou, M, Dai, L.C, Li, C.M, Shi, L.X, Huang, Y, Guo, Z.Q. | Deposit date: | 2020-03-06 | Release date: | 2020-09-23 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis of nucleosome dynamics modulation by histone variants H2A.B and H2A.Z.2.2. Embo J., 40, 2021
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3U5P
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![BU of 3u5p by Molmil](/molmil-images/mine/3u5p) | |
3WKJ
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![BU of 3wkj by Molmil](/molmil-images/mine/3wkj) | The nucleosome containing human TSH2B | Descriptor: | CHLORIDE ION, DNA (145-MER), Histone H2A type 1-B/E, ... | Authors: | Urahama, T, Horikoshi, N, Osakabe, A, Tachiwana, H, Kurumizaka, H. | Deposit date: | 2013-10-22 | Release date: | 2014-04-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of human nucleosome containing the testis-specific histone variant TSH2B. Acta Crystallogr.,Sect.F, 70, 2014
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5C11
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![BU of 5c11 by Molmil](/molmil-images/mine/5c11) | |