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4FWF

Complex structure of LSD2/AOF1/KDM1b with H3K4 mimic

Summary for 4FWF
Entry DOI10.2210/pdb4fwf/pdb
Related4FWE 4FWJ
DescriptorLysine-specific histone demethylase 1B, Histone H3.1, ZINC ION, ... (5 entities in total)
Functional Keywordslsd2, fad, histone demethylase, c4h2c2, cw, histone, epigenetic, oxidoreductase-protein binding complex, oxidoreductase/protein binding
Biological sourceHomo sapiens (human)
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Cellular locationNucleus (By similarity): Q8NB78
Nucleus: P68431
Total number of polymer chains2
Total formula weight92515.34
Authors
Zhang, Q.,Chen, Z. (deposition date: 2012-07-01, release date: 2013-01-16, Last modification date: 2023-11-08)
Primary citationZhang, Q.,Qi, S.,Xu, M.,Yu, L.,Tao, Y.,Deng, Z.,Wu, W.,Li, J.,Chen, Z.,Wong, J.
Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b
Cell Res., 23:225-241, 2013
Cited by
PubMed: 23266887
DOI: 10.1038/cr.2012.177
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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