4FWF
Complex structure of LSD2/AOF1/KDM1b with H3K4 mimic
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific histone demethylase 1B | polymer | 796 | 89341.0 | 1 | UniProt (Q8NB78) Pfam (PF07496) Pfam (PF04433) Pfam (PF01593) | Homo sapiens (human) | Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2 |
| 2 | B (E) | Histone H3.1 | polymer | 20 | 2192.6 | 1 | UniProt (P68431) | Homo sapiens | |
| 3 | C, D, E (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | F (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 5 | G (A) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A: 30 - 822 (UniProt: Q8NB78)
E: 1 - 20 (UniProt: P68431)
| PDB | External Database | Details |
|---|---|---|
| Gly 27 | - | expression tag |
| His 28 | - | expression tag |
| Met 29 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 4 | Lys 5 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 91533.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 981.8 | |
| All* | Total formula weight | 92515.3 |
