8DK5

Structure of 187bp LIN28b nucleosome with site 0 mutation

Summary for 8DK5

• Entry DOI: 10.2210/pdb8dk5/pdb
• Related: 7U0G 7U0I 7U0J
• EMDB information: 27483
• Descriptor: Histone H3.1, Histone H4, Histone H2A type 2-C, ... (7 entities in total)
• Functional Keywords: nucleosome, transcription, chromatin binding protein-dna complex, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 283099.68

Authors

Lian, T.,Guan, R.,Bai, Y. (deposition date: 2022-07-02, release date: 2023-06-28)

• Primary citation: Guan, R.,Lian, T.,Zhou, B.R.,Wheeler, D.,Bai, Y.; Structural mechanism of LIN28B nucleosome targeting by OCT4.; Mol.Cell, 83:1970-1982.e6, 2023; PubMed: 37327775; DOI: 10.1016/j.molcel.2023.05.030

Experimental method

ELECTRON MICROSCOPY (2.71 Å)