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8DK5

Structure of 187bp LIN28b nucleosome with site 0 mutation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(A, E)
Histone H3.1polymer13615437.22UniProt (P68431)
Pfam (PF00125)
Homo sapiens (human)Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
2B, F
(B, F)
Histone H4polymer10311394.42UniProt (P62805)
Pfam (PF15511)
Homo sapiens (human)
3C, G
(C, G)
Histone H2A type 2-Cpolymer12914017.42UniProt (Q16777)
Pfam (PF00125)
Pfam (PF16211)
Homo sapiens (human)H2A-clustered histone 20,Histone H2A-GL101,Histone H2A/q
4D, H
(D, H)
Histone H2B type 2-Epolymer12613951.22UniProt (Q16778)
Pfam (PF00125)
Homo sapiens (human)H2B-clustered histone 21,Histone H2B-GL105,Histone H2B.q,H2B/q
5I, J
(K, N)
Single-chain variable fragmentpolymer26529030.12Mus musculus
6K
(I)
DNA (187-MER)polymer18758223.41GenBank (2225930)Homo sapiens
7L
(J)
DNA (187-MER)polymer18757215.51GenBank (2225930)Homo sapiens
Sequence modifications
I: -9 - 177 (GenBank: 2225930)
PDBExternal DatabaseDetails
Da 6-insertion
Dg 7Dt 34520conflict
Dg 9Dt 34518conflict
Da 10Dt 34517conflict
Dg 13Dc 34514conflict
-Dt 34512deletion
J: -14 - 172 (GenBank: 2225930)
PDBExternal DatabaseDetails
-Da 34512deletion
Dc 150Dg 34514conflict
Dt 153Da 34517conflict
Dc 154Da 34518conflict
Dc 156Da 34520conflict
Dt 157-insertion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight283099.7
All*Total formula weight283099.7
*Water molecules are not included.

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PDB entries from 2024-11-06

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