7CGT
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7CCS
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![BU of 7ccs by Molmil](/molmil-images/mine/7ccs) | Consensus mutated xCT-CD98hc complex | Descriptor: | 4F2 cell-surface antigen heavy chain, Consensus mutated Anionic Amino Acid Transporter Light Chain, Xc- System | Authors: | Oda, K, Lee, Y, Takemoto, M, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2020-06-17 | Release date: | 2020-12-09 | Last modified: | 2020-12-16 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Consensus mutagenesis approach improves the thermal stability of system x c - transporter, xCT, and enables cryo-EM analyses. Protein Sci., 29, 2020
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4AIE
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![BU of 4aie by Molmil](/molmil-images/mine/4aie) | Structure of glucan-1,6-alpha-glucosidase from Lactobacillus acidophilus NCFM | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLUCAN 1,6-ALPHA-GLUCOSIDASE, ... | Authors: | Fredslund, F, Navarro Poulsen, J.C, Lo Leggio, L. | Deposit date: | 2012-02-09 | Release date: | 2012-08-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Enzymology and Structure of the Gh13_31 Glucan 1,6-Alpha-Glucosidase that Confers Isomaltooligosaccharide Utilization in the Probiotic Lactobacillus Acidophilus Ncfm. J.Bacteriol., 194, 2012
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8WNS
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![BU of 8wns by Molmil](/molmil-images/mine/8wns) | Cryo EM map of SLC7A10 in the apo state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1 | Authors: | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | Deposit date: | 2023-10-06 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Cryo-EM structure of the human Asc-1 transporter complex. Nat Commun, 15, 2024
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8WNY
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![BU of 8wny by Molmil](/molmil-images/mine/8wny) | Cryo EM map of SLC7A10-SLC3A2 complex in the D-serine bound state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1, ... | Authors: | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | Deposit date: | 2023-10-06 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of the human Asc-1 transporter complex. Nat Commun, 15, 2024
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8WNT
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![BU of 8wnt by Molmil](/molmil-images/mine/8wnt) | Cryo EM map of SLC7A10 with L-Alanine substrate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALANINE, ... | Authors: | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | Deposit date: | 2023-10-06 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Cryo-EM structure of the human Asc-1 transporter complex. Nat Commun, 15, 2024
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4BZY
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![BU of 4bzy by Molmil](/molmil-images/mine/4bzy) | Crystal structure of human glycogen branching enzyme (GBE1) | Descriptor: | 1,4-ALPHA-GLUCAN-BRANCHING ENZYME | Authors: | Froese, D.S, Krojer, T, Goubin, S, Strain-Damerell, C, Mahajan, P, von Delft, F, Burgess-Brown, N, Bountra, C, Arrowsmith, C.H, Edwards, A, Yue, W.W. | Deposit date: | 2013-07-30 | Release date: | 2013-09-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural Basis of Glycogen Branching Enzyme Deficiency and Pharmacologic Rescue by Rational Peptide Design. Hum.Mol.Genet., 24, 2015
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8XPU
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![BU of 8xpu by Molmil](/molmil-images/mine/8xpu) | Overall structure of the LAT1-4F2hc bound with JPH203 | Descriptor: | (2~{S})-2-azanyl-3-[4-[(5-azanyl-2-phenyl-1,3-benzoxazol-7-yl)methoxy]-3,5-bis(chloranyl)phenyl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 5 of Amino acid transporter heavy chain SLC3A2, ... | Authors: | Hu, Z, Yan, R. | Deposit date: | 2024-01-04 | Release date: | 2024-07-17 | Last modified: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for the inhibition mechanism of LAT1-4F2hc complex by JPH203. Cell Discov, 10, 2024
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7D9C
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![BU of 7d9c by Molmil](/molmil-images/mine/7d9c) | Alpha-glucosidase from Weissella cibaria BBK-1 bound with maltose | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Alpha-glycosidase, CALCIUM ION, ... | Authors: | Krusong, K, Wangpaiboon, K, Kim, S, Mori, T, Hakoshima, T. | Deposit date: | 2020-10-13 | Release date: | 2021-08-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | A GH13 alpha-glucosidase from Weissella cibaria uncommonly acts on short-chain maltooligosaccharides. Acta Crystallogr D Struct Biol, 77, 2021
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3ZO9
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![BU of 3zo9 by Molmil](/molmil-images/mine/3zo9) | The structure of Trehalose Synthase (TreS) of Mycobacterium smegmatis | Descriptor: | CALCIUM ION, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Caner, S, Nguyen, N, Aguda, A, Zhang, R, Pan, Y.T, Withers, S.G, Brayer, G.D. | Deposit date: | 2013-02-21 | Release date: | 2013-07-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | The Structure of the Mycobacterium Smegmatis Trehalose Synthase Reveals an Unusual Active Site Configuration and Acarbose-Binding Mode. Glycobiology, 23, 2013
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4AEF
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![BU of 4aef by Molmil](/molmil-images/mine/4aef) | THE CRYSTAL STRUCTURE OF THERMOSTABLE AMYLASE FROM THE PYROCOCCUS | Descriptor: | NEOPULLULANASE (ALPHA-AMYLASE II) | Authors: | Song, H.-N, Jung, T.-Y, Yoon, S.-M, Yang, S.-J, Park, K.-H, Woo, E.-J. | Deposit date: | 2012-01-10 | Release date: | 2012-10-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | A Novel Domain Arrangement in a Monomeric Cyclodextrin-Hydrolyzing Enzyme from the Hyperthermophile Pyrococcus Furiosus. Biochim.Biophys.Acta, 1834, 2013
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4AEE
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![BU of 4aee by Molmil](/molmil-images/mine/4aee) | CRYSTAL STRUCTURE OF MALTOGENIC AMYLASE FROM S.MARINUS | Descriptor: | ALPHA AMYLASE, CATALYTIC REGION | Authors: | Jung, T.Y, Park, C.H, Yoon, S.M, Park, S.H, Park, K.H, Woo, E.J. | Deposit date: | 2012-01-10 | Release date: | 2012-01-18 | Last modified: | 2012-03-21 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Association of Novel Domain in Active Site of Archaic Hyperthermophilic Maltogenic Amylase from Staphylothermus Marinus. J.Biol.Chem., 287, 2012
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9CGT
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![BU of 9cgt by Molmil](/molmil-images/mine/9cgt) | STRUCTURE OF CYCLODEXTRIN GLYCOSYLTRANSFERASE COMPLEXED WITH A THIO-MALTOPENTAOSE | Descriptor: | CALCIUM ION, PROTEIN (CYCLODEXTRIN-GLYCOSYLTRANSFERASE), alpha-D-glucopyranose-(1-4)-4-thio-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-4-thio-alpha-D-glucopyranose-(1-4)-1-thio-alpha-D-glucopyranose | Authors: | Schmidt, A.K, Schulz, G.E. | Deposit date: | 1998-09-27 | Release date: | 1998-10-14 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Substrate binding to a cyclodextrin glycosyltransferase and mutations increasing the gamma-cyclodextrin production. Eur.J.Biochem., 255, 1998
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4CGT
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7DF1
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![BU of 7df1 by Molmil](/molmil-images/mine/7df1) | Crystal structure of human CD98 heavy chain extracellular domain in complex with S1-F4 scFv | Descriptor: | 4F2 cell-surface antigen heavy chain, IGL c2062_light_IGKV4-1_IGKJ5, S1-F4 VH | Authors: | Liu, X, Ding, J, Sui, J, Tian, X. | Deposit date: | 2020-11-06 | Release date: | 2022-12-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.806 Å) | Cite: | An anti-CD98 antibody displaying pH-dependent Fc-mediated tumour-specific activity against multiple cancers in CD98-humanized mice. Nat Biomed Eng, 2022
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7DSL
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![BU of 7dsl by Molmil](/molmil-images/mine/7dsl) | Overall structure of the LAT1-4F2hc bound with JX-078 | Descriptor: | (2~{S})-2-azanyl-7-[(2-phenylphenyl)methoxy]-3,4-dihydro-1~{H}-naphthalene-2-carboxylic acid, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yan, R.H, Li, Y.N, Zhang, Y.Y, Zhong, X.Y, Zhou, Q. | Deposit date: | 2020-12-31 | Release date: | 2021-03-10 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter. Cell Discov, 7, 2021
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7DSQ
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![BU of 7dsq by Molmil](/molmil-images/mine/7dsq) | Overall structure of the LAT1-4F2hc bound with 3,5-diiodo-L-tyrosine | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,5-DIIODOTYROSINE, ... | Authors: | Yan, R.H, Li, Y.N, Zhang, Y.Y, Zhong, X.Y, Zhou, Q. | Deposit date: | 2020-12-31 | Release date: | 2021-03-10 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter. Cell Discov, 7, 2021
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7DSN
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![BU of 7dsn by Molmil](/molmil-images/mine/7dsn) | Overall structure of the LAT1-4F2hc bound with JX-119 | Descriptor: | (2~{S})-2-azanyl-7-[[2-(1,3-benzoxazol-2-yl)phenyl]methoxy]-3,4-dihydro-1~{H}-naphthalene-2-carboxylic acid, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yan, R.H, Li, Y.N, Zhang, Y.Y, Zhong, X.Y, Zhou, Q. | Deposit date: | 2020-12-31 | Release date: | 2021-03-10 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter. Cell Discov, 7, 2021
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7DSK
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![BU of 7dsk by Molmil](/molmil-images/mine/7dsk) | Overall structure of the LAT1-4F2hc bound with JX-075 | Descriptor: | (2~{S})-2-azanyl-7-(naphthalen-1-ylmethoxy)-3,4-dihydro-1~{H}-naphthalene-2-carboxylic acid, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yan, R.H, Li, Y.N, Zhang, Y.Y, Zhong, X.Y, Zhou, Q. | Deposit date: | 2020-12-31 | Release date: | 2021-03-10 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter. Cell Discov, 7, 2021
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8YIF
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![BU of 8yif by Molmil](/molmil-images/mine/8yif) | Crystal structure of GH13_30 alpha-glucosidase CmmB in complex with acarviosin | Descriptor: | Acarviosin, Alpha-glucosidase | Authors: | Saburi, W, Tagami, T, Yu, J, Ose, T, Yao, M, Mori, H. | Deposit date: | 2024-02-29 | Release date: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Molecular mechanism for the substrate specificity of Arthrobacter globiformis M6 alpha-glucosidase CmmB, belonging to glycoside hydrolase family 13 subfamily 30 Food Biosci, 61, 2024
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8UZH
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8UQV
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8YIE
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![BU of 8yie by Molmil](/molmil-images/mine/8yie) | Crystal structure of GH13_30 alpha-glucosidase CmmB in complex with acarbose | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Alpha-glucosidase | Authors: | Saburi, W, Tagami, T, Yu, J, Ose, T, Yao, M, Mori, H. | Deposit date: | 2024-02-29 | Release date: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular mechanism for the substrate specificity of Arthrobacter globiformis M6 alpha-glucosidase CmmB, belonging to glycoside hydrolase family 13 subfamily 30 Food Biosci, 61, 2024
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7EAV
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![BU of 7eav by Molmil](/molmil-images/mine/7eav) | The X-ray crystallographic structure of glycogen debranching enzyme from Sulfolobus solfataricus STB09 | Descriptor: | Glycogen debranching enzyme | Authors: | Li, Z.F, Ban, X.F, Tian, Y.X, Li, C.M, Cheng, L, Hong, Y, Gu, Z.B. | Deposit date: | 2021-03-08 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.803 Å) | Cite: | The X-ray Crystallographic Structure of Debranching Enzyme from Sulfolobus solfataricus STB09 To Be Published
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4AYS
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![BU of 4ays by Molmil](/molmil-images/mine/4ays) | The Structure of Amylosucrase from D. radiodurans | Descriptor: | AMYLOSUCRASE | Authors: | Skov, L.K, Pizzut, S, Remaud-Simeon, M, Gajhede, M, Mirza, O. | Deposit date: | 2012-06-21 | Release date: | 2013-09-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | The Structure of Amylosucrase from Deinococcus Radiodurans Has an Unusual Open Active-Site Topology Acta Crystallogr.,Sect.F, 69, 2013
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