7CCS

Consensus mutated xCT-CD98hc complex

Summary for 7CCS

Entry DOI	10.2210/pdb7ccs/pdb
EMDB information	30341
Descriptor	4F2 cell-surface antigen heavy chain, Consensus mutated Anionic Amino Acid Transporter Light Chain, Xc- System (2 entities in total)
Functional Keywords	transporter, membrane protein, complex, transport protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	124003.48
Authors	Oda, K.,Lee, Y.,Takemoto, M.,Yamashita, K.,Nishizawa, T.,Nureki, O. (deposition date: 2020-06-17, release date: 2020-12-09, Last modification date: 2020-12-16)
Primary citation	Oda, K.,Lee, Y.,Wiriyasermkul, P.,Tanaka, Y.,Takemoto, M.,Yamashita, K.,Nagamori, S.,Nishizawa, T.,Nureki, O. Consensus mutagenesis approach improves the thermal stability of system x c - transporter, xCT, and enables cryo-EM analyses. Protein Sci., 29:2398-2407, 2020 Cited by PubMed: 33016372 DOI: 10.1002/pro.3966 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (6.2 Å)

Structure validation