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7DSN

Overall structure of the LAT1-4F2hc bound with JX-119

Summary for 7DSN
Entry DOI10.2210/pdb7dsn/pdb
EMDB information30839
Descriptor4F2 cell-surface antigen heavy chain, Large neutral amino acids transporter small subunit 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywordslat1-4f2hc, membrane protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight131138.23
Authors
Yan, R.H.,Li, Y.N.,Zhang, Y.Y.,Zhong, X.Y.,Zhou, Q. (deposition date: 2020-12-31, release date: 2021-03-10, Last modification date: 2022-06-29)
Primary citationYan, R.,Li, Y.,Muller, J.,Zhang, Y.,Singer, S.,Xia, L.,Zhong, X.,Gertsch, J.,Altmann, K.H.,Zhou, Q.
Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter.
Cell Discov, 7:16-16, 2021
Cited by
PubMed: 33758168
DOI: 10.1038/s41421-021-00247-4
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.1 Å)
Structure validation

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