8XPU

Overall structure of the LAT1-4F2hc bound with JPH203

Summary for 8XPU

Entry DOI	10.2210/pdb8xpu/pdb
EMDB information	38561
Descriptor	Isoform 5 of Amino acid transporter heavy chain SLC3A2, Large neutral amino acids transporter small subunit 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	transporter, slc family, inhibitor, transport protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	129517.65
Authors	Yan, R.,Hu, Z. (deposition date: 2024-01-04, release date: 2024-07-17)
Primary citation	Hu, Z.,Yan, R. Structural basis for the inhibition mechanism of LAT1-4F2hc complex by JPH203. Cell Discov, 10:73-73, 2024 Cited by PubMed: 38956038 DOI: 10.1038/s41421-024-00697-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation