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4W5Q
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BU of 4w5q by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-8
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
4W5R
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BU of 4w5r by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-8 (Long Target)
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
5OMQ
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BU of 5omq by Molmil
Ternary complex of 9N DNA polymerase in the replicative state with three metal ions in the active site
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA Primer, DNA Template, ...
Authors:Betz, K, Marx, A, Diederichs, K.
Deposit date:2017-08-01
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Crystal structures of ternary complexes of archaeal B-family DNA polymerases.
PLoS ONE, 12, 2017
5OMV
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BU of 5omv by Molmil
Ternary complex of 9N DNA polymerase in the replicative state with two metal ions in the active site
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA polymerase, DNA primer, ...
Authors:Betz, K, Marx, A, Diederichs, K.
Deposit date:2017-08-01
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Crystal structures of ternary complexes of archaeal B-family DNA polymerases.
PLoS ONE, 12, 2017
5VVR
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BU of 5vvr by Molmil
Ternary complex of RNA Pol II, transcription scaffold and Rad26
Descriptor: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
Authors:Lahiri, I, Leschziner, A.E.
Deposit date:2017-05-19
Release date:2017-11-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structural basis for the initiation of eukaryotic transcription-coupled DNA repair.
Nature, 551, 2017
6DRD
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BU of 6drd by Molmil
RNA Pol II(G)
Descriptor: DNA-directed RNA polymerase II subunit GRINL1A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ...
Authors:Yu, X, Jishage, M, Shi, Y, Ganesan, S, Sali, A, Chait, B.T, Asturias, F, Roeder, R.G.
Deposit date:2018-06-11
Release date:2019-06-12
Last modified:2019-12-04
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1.
Nat. Struct. Mol. Biol., 25, 2018
4W5T
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BU of 4w5t by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-7
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
4W5O
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BU of 4w5o by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-9
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
4W5N
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BU of 4w5n by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Defined Guide RNA
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
8PJB
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BU of 8pjb by Molmil
Cryo-EM structure of MLE in complex with UUC RNA and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ...
Authors:Jagtap, P.K.A, Hennig, J.
Deposit date:2023-06-23
Release date:2023-11-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023
8PJJ
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BU of 8pjj by Molmil
Cryo-EM structure of MLE in complex with SL7UUC RNA and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, SL7UUC RNA
Authors:Jagtap, P.K.A, Hennig, J.
Deposit date:2023-06-23
Release date:2023-11-22
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.24 Å)
Cite:Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023
5VVS
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BU of 5vvs by Molmil
RNA pol II elongation complex
Descriptor: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Lahiri, I, Leschziner, A.E.
Deposit date:2017-05-20
Release date:2017-11-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Structural basis for the initiation of eukaryotic transcription-coupled DNA repair.
Nature, 551, 2017
6Y0C
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BU of 6y0c by Molmil
Influenza C virus polymerase in complex with human ANP32A - Subclass 2
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*CP*CP*UP*UP*UP*U)-3'), ...
Authors:Fan, H, Carrique, L, Keown, J.R, Grimes, J.M, Fodor, E.
Deposit date:2020-02-07
Release date:2020-11-25
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
6XZD
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BU of 6xzd by Molmil
Influenza C virus polymerase complex without chicken ANP32A - Subclass 2
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*CP*CP*CP*UP*GP*C)-3'), ...
Authors:Keown, J.R, Carrique, L, Fan, H, Grimes, J.M, Fodor, E.
Deposit date:2020-02-04
Release date:2020-12-23
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
6MDZ
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BU of 6mdz by Molmil
Human Argonaute2-miR-122 bound to a target RNA with two central mismatches (bu2)
Descriptor: PHENOL, Protein argonaute-2, RNA (5'-R(P*AP*AP*AP*CP*AP*CP*CP*AP*UP*UP*UP*CP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), ...
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-09-05
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
6MFR
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BU of 6mfr by Molmil
Human Argonaute2-miR-122 bound to a target RNA with three central mismatches (bu3)
Descriptor: PHENOL, PHOSPHATE ION, Protein argonaute-2, ...
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-09-12
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
6MFN
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BU of 6mfn by Molmil
Human Argonaute2-miR-27a bound to HSUR1 target RNA
Descriptor: PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*CP*UP*GP*UP*GP*AP*UP*AP*A)-3'), ...
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-09-11
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
6NIT
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BU of 6nit by Molmil
Human Argonaute2-miR-122 bound to a target RNA with four central mismatches (bu4)
Descriptor: Protein argonaute-2, RNA (5'-R(P*AP*AP*CP*AP*CP*CP*AP*UP*CP*CP*AP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3')
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-12-31
Release date:2019-08-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
4Z4H
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BU of 4z4h by Molmil
Human Argonaute2 A481T Mutant Bound to t1-A Target RNA
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2015-04-02
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4I
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BU of 4z4i by Molmil
Human Argonaute2 A481T Mutant Bound to t1-G Target RNA
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2015-04-02
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4F
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BU of 4z4f by Molmil
Human Argonaute2 Bound to t1-DAP Target RNA
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2015-04-02
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4D
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BU of 4z4d by Molmil
Human Argonaute2 Bound to t1-G Target RNA
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2015-04-02
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4E
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BU of 4z4e by Molmil
Human Argonaute2 Bound to t1-U Target RNA
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2015-04-02
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4G
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BU of 4z4g by Molmil
Human Argonaute2 Bound to t1-Inosine Target RNA
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2015-04-02
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4C
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BU of 4z4c by Molmil
Human Argonaute2 Bound to t1-C Target RNA
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2015-04-02
Release date:2015-09-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015

224201

数据于2024-08-28公开中

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