4Z4H
Human Argonaute2 A481T Mutant Bound to t1-A Target RNA
Summary for 4Z4H
Entry DOI | 10.2210/pdb4z4h/pdb |
Related | 4Z4C 4Z4D 4Z4E 4Z4F 4Z4G 4Z4I |
Descriptor | Protein argonaute-2, RNA (5'-R(P*UP*UP*CP*AP*CP*AP*UP*UP*GP*CP*CP*CP*AP*AP*GP*UP*CP*UP*UP*U)-3'), RNA (5'-R(*CP*AP*AP*UP*GP*UP*GP*A)-3'), ... (6 entities in total) |
Functional Keywords | argonaute2, gene regulation-rna complex, gene regulation/rna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 107943.64 |
Authors | Schirle, N.T.,MacRae, I.J. (deposition date: 2015-04-02, release date: 2015-09-23, Last modification date: 2023-09-27) |
Primary citation | Schirle, N.T.,Sheu-Gruttadauria, J.,Chandradoss, S.D.,Joo, C.,MacRae, I.J. Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets. Elife, 4:-, 2015 Cited by PubMed: 26359634DOI: 10.7554/eLife.07646 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.504 Å) |
Structure validation
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