8B8S
 
 | | Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3 | | Descriptor: | Serine/arginine (SR)-type shuttling mRNA binding protein NPL3 | | Authors: | Kachariya, N, Sattler, M, Keil, P, Strasser, K. | | Deposit date: | 2022-10-04 | | Release date: | 2022-11-09 | | Last modified: | 2023-02-08 | | Method: | SOLUTION NMR, SOLUTION SCATTERING | | Cite: | Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic Acids Res., 51, 2023
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8ANY
 | | Human mitochondrial ribosome in complex with LRPPRC, SLIRP, A-site, P-site, E-site tRNAs and mRNA | | Descriptor: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | | Authors: | Singh, V, Itoh, Y, Amunts, A. | | Deposit date: | 2022-08-06 | | Release date: | 2023-08-16 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Structural basis of LRPPRC-SLIRP-dependent translation by the
mitoribosome
To Be Published
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8A98
 | | CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT | | Descriptor: | 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ... | | Authors: | Rajan, K.S, Yonath, A, Bashan, A. | | Deposit date: | 2022-06-28 | | Release date: | 2023-10-11 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.46 Å) | | Cite: | Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Cell Rep, 43, 2024
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8A3W
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7ZUG
 | | Heterogeneous nuclear ribonucleoprotein H1, qRRM2 domain | | Descriptor: | CHLORIDE ION, Heterogeneous nuclear ribonucleoprotein H, N-terminally processed, ... | | Authors: | Winter, N, Kumar, M, Isupov, M.N, Wiener, R. | | Deposit date: | 2022-05-12 | | Release date: | 2023-05-24 | | Method: | X-RAY DIFFRACTION (1.075 Å) | | Cite: | Heterogeneous nuclear ribonucleoprotein H1, qRRM2 domain
To Be Published
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7ZNK
 | | Structure of an endogenous human TREX complex bound to mRNA | | Descriptor: | RNA, Spliceosome RNA helicase DDX39B, THO complex subunit 1, ... | | Authors: | Pacheco-Fiallos, F.B, Vorlaender, M.K, Plaschka, C. | | Deposit date: | 2022-04-21 | | Release date: | 2023-05-03 | | Last modified: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | mRNA recognition and packaging by the human transcription-export complex.
Nature, 616, 2023
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7ZNJ
 | | Structure of an ALYREF-exon junction complex hexamer | | Descriptor: | Eukaryotic initiation factor 4A-III, N-terminally processed, MAGNESIUM ION, ... | | Authors: | Pacheco-Fiallos, F.B, Vorlaender, M.K, Plaschka, C. | | Deposit date: | 2022-04-21 | | Release date: | 2023-04-12 | | Last modified: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | mRNA recognition and packaging by the human transcription-export complex.
Nature, 616, 2023
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7ZJ2
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7ZIR
 | | Cryo-EM structure of hnRNPDL amyloid fibrils | | Descriptor: | Heterogeneous nuclear ribonucleoprotein D-like | | Authors: | Garcia-Pardo, J, Chaves-Sanjuan, A, Bartolome-Nafria, A, Gil-Garcia, M, Visentin, C, Bolognesi, M, Ricagno, S, Ventura, S. | | Deposit date: | 2022-04-08 | | Release date: | 2022-12-28 | | Last modified: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Cryo-EM structure of hnRNPDL-2 fibrils, a functional amyloid associated with limb-girdle muscular dystrophy D3.
Nat Commun, 14, 2023
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7ZHR
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7ZEZ
 | | Trimolecular complex Cyp33-RRMdelta alpha : MLL1-PHD3 : H3K4me3 | | Descriptor: | Histone H3, Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, MLL cleavage product N320, ... | | Authors: | Blatter, M, Allain, F, Meylan, C. | | Deposit date: | 2022-03-31 | | Release date: | 2022-04-13 | | Last modified: | 2023-05-03 | | Method: | SOLUTION NMR | | Cite: | RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
Sci Adv, 9, 2023
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7ZEY
 | | Complex Cyp33-RRM : MLL1-PHD3 | | Descriptor: | MLL cleavage product N320, Peptidyl-prolyl cis-trans isomerase E, ZINC ION | | Authors: | Blatter, M, Allain, F, Meylan, C. | | Deposit date: | 2022-03-31 | | Release date: | 2022-04-13 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
Sci Adv, 9, 2023
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7ZEX
 | | Complex Cyp33-RRMdelta alpha : UAAUGUCG RNA | | Descriptor: | Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, RNA (5'-R(*UP*AP*AP*UP*GP*UP*CP*G)-3') | | Authors: | Blatter, M, Allain, F, Meylan, C. | | Deposit date: | 2022-03-31 | | Release date: | 2022-05-04 | | Last modified: | 2023-05-03 | | Method: | SOLUTION NMR | | Cite: | RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
Sci Adv, 9, 2023
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7ZEW
 | | Complex Cyp33-RRM : AAUAAA RNA | | Descriptor: | Peptidyl-prolyl cis-trans isomerase E, RNA (5'-R(*AP*AP*UP*AP*AP*A)-3') | | Authors: | Blatter, M, Allain, F, Meylan, C. | | Deposit date: | 2022-03-31 | | Release date: | 2022-04-13 | | Last modified: | 2023-05-03 | | Method: | SOLUTION NMR | | Cite: | RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
Sci Adv, 9, 2023
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7ZEV
 | | Free form of extended Cyp33-RRM | | Descriptor: | Peptidyl-prolyl cis-trans isomerase E | | Authors: | Blatter, M, Allain, F, Meylan, C. | | Deposit date: | 2022-03-31 | | Release date: | 2022-04-13 | | Last modified: | 2023-05-03 | | Method: | SOLUTION NMR | | Cite: | RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
Sci Adv, 9, 2023
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7ZAP
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7Z3X
 | | Crystal structure of FIR RRM1-2 Y115F mutant bound to FUSE ssDNA | | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*T)-3'), DNA (5'-D(P*GP*TP*())-3'), ... | | Authors: | Ni, X, Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2022-03-02 | | Release date: | 2022-11-09 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal structure of FIR RRM1-2 Y115F mutant bound to FUSE ssDNA
To Be Published
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7YEX
 | | Structure of MmIGF2BP3 in complex with 8-mer RNA | | Descriptor: | Insulin-like growth factor 2 mRNA-binding protein 3, RNA (5'-R(P*CP*AP*CP*AP*CP*AP*CP*A)-3') | | Authors: | Li, X.J, Wu, B.X. | | Deposit date: | 2022-07-06 | | Release date: | 2023-07-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of MmIGF2BP3 in complex with 8-mer RNA
To Be Published
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7YEW
 | | Structure of MmIGF2BP3 in complex with 7-mer RNA | | Descriptor: | Insulin-like growth factor 2 mRNA-binding protein 3, RNA (5'-R(P*CP*AP*CP*AP*CP*AP*C)-3') | | Authors: | Li, X.J, Wu, B.X. | | Deposit date: | 2022-07-06 | | Release date: | 2023-07-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of MmIGF2BP3 in complex with 7-mer RNA
To Be Published
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7YCX
 | | The structure of INTAC-PEC complex | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Zheng, H, Jin, Q, Wang, X, Qi, Y, Liu, W, Ren, Y, Zhao, D, Chen, F.X, Cheng, J, Chen, X, Xu, Y. | | Deposit date: | 2022-07-02 | | Release date: | 2023-03-15 | | Last modified: | 2023-09-27 | | Method: | ELECTRON MICROSCOPY (4.18 Å) | | Cite: | Structural basis of INTAC-regulated transcription.
Protein Cell, 14, 2023
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7XX9
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7XX8
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7WM3
 | | hnRNP A2/B1 RRMs in complex with single-stranded DNA | | Descriptor: | DNA (5'-D(P*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), Heterogeneous nuclear ribonucleoproteins A2/B1 | | Authors: | Abula, A, Liu, Y, Guo, H, Li, T, Ji, X. | | Deposit date: | 2022-01-14 | | Release date: | 2022-06-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Structural Insight Into hnRNP A2/B1 Homodimerization and DNA Recognition.
J.Mol.Biol., 435, 2022
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7WEZ
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7W5B
 | | The cryo-EM structure of human C* complex | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | | Authors: | Zhan, X, Lu, Y, Shi, Y. | | Deposit date: | 2021-11-29 | | Release date: | 2022-06-22 | | Last modified: | 2022-08-17 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
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