2JDO
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![BU of 2jdo by Molmil](/molmil-images/mine/2jdo) | STRUCTURE OF PKB-BETA (AKT2) COMPLEXED WITH ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY) ETHYLAMINO)ETHYL)AMIDE | Descriptor: | 1,2-ETHANEDIOL, GLYCOGEN SYNTHASE KINASE-3 BETA, ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE, ... | Authors: | Davies, T.G, Verdonk, M.L, Graham, B, Saalau-Bethell, S, Hamlett, C.C.F, Mchardy, T, Collins, I, Garrett, M.D, Workman, P, Woodhead, S.J, Jhoti, H, Barford, D. | Deposit date: | 2007-01-11 | Release date: | 2007-02-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Structural Comparison of Inhibitor Binding to Pkb, Pka and Pka-Pkb Chimera J.Mol.Biol., 367, 2007
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4R3Z
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![BU of 4r3z by Molmil](/molmil-images/mine/4r3z) | Crystal structure of human ArgRS-GlnRS-AIMP1 complex | Descriptor: | Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Arginine--tRNA ligase, cytoplasmic, ... | Authors: | Fu, Y, Kim, Y, Cho, Y. | Deposit date: | 2014-08-18 | Release date: | 2014-10-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (4.033 Å) | Cite: | Structure of the ArgRS-GlnRS-AIMP1 complex and its implications for mammalian translation Proc.Natl.Acad.Sci.USA, 111, 2014
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1KH1
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![BU of 1kh1 by Molmil](/molmil-images/mine/1kh1) | |
1KOR
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![BU of 1kor by Molmil](/molmil-images/mine/1kor) | Crystal Structure of Thermus thermophilus HB8 Argininosuccinate Synthetase in complex with inhibitors | Descriptor: | ARGININE, Argininosuccinate Synthetase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Goto, M, Nakajima, Y, Hirotsu, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-12-22 | Release date: | 2002-04-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of argininosuccinate synthetase from Thermus thermophilus HB8. Structural basis for the catalytic action. J.Biol.Chem., 277, 2002
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1JW9
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![BU of 1jw9 by Molmil](/molmil-images/mine/1jw9) | Structure of the Native MoeB-MoaD Protein Complex | Descriptor: | MOLYBDOPTERIN BIOSYNTHESIS MOEB PROTEIN, MOLYBDOPTERIN [MPT] CONVERTING FACTOR, SUBUNIT 1, ... | Authors: | Lake, M.W, Wuebbens, M.M, Rajagopalan, K.V, Schindelin, H. | Deposit date: | 2001-09-03 | Release date: | 2001-11-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex. Nature, 414, 2001
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6IYL
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![BU of 6iyl by Molmil](/molmil-images/mine/6iyl) | The structure of EntE with 3-cyanobenzoyl adenylate analog | Descriptor: | 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex, 5'-O-[(3-cyanobenzene-1-carbonyl)sulfamoyl]adenosine | Authors: | Miyanaga, A, Ishikawa, F. | Deposit date: | 2018-12-17 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | An Engineered Aryl Acid Adenylation Domain with an Enlarged Substrate Binding Pocket. Angew.Chem.Int.Ed.Engl., 58, 2019
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1MBZ
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![BU of 1mbz by Molmil](/molmil-images/mine/1mbz) | BETA-LACTAM SYNTHETASE WITH TRAPPED INTERMEDIATE | Descriptor: | ARGININE-N-METHYLCARBONYL PHOSPHORIC ACID 5'-ADENOSINE ESTER, BETA-LACTAM SYNTHETASE, GLYCEROL, ... | Authors: | Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C. | Deposit date: | 2002-08-04 | Release date: | 2002-10-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots Proc.Natl.Acad.Sci.USA, 99, 2002
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1MC1
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![BU of 1mc1 by Molmil](/molmil-images/mine/1mc1) | BETA-LACTAM SYNTHETASE WITH PRODUCT (DGPC), AMP AND PPI | Descriptor: | ADENOSINE MONOPHOSPHATE, BETA-LACTAM SYNTHETASE, DEOXYGUANIDINOPROCLAVAMINIC ACID, ... | Authors: | Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C. | Deposit date: | 2002-08-04 | Release date: | 2002-10-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots Proc.Natl.Acad.Sci.USA, 99, 2002
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4MRT
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![BU of 4mrt by Molmil](/molmil-images/mine/4mrt) | Structure of the Phosphopantetheine Transferase Sfp in Complex with Coenzyme A and a Peptidyl Carrier Protein | Descriptor: | 4'-phosphopantetheinyl transferase sfp, COENZYME A, GLYCEROL, ... | Authors: | Tufar, P, Rahighi, S, Kraas, F.I, Kirchner, D.K, Loehr, F, Henrich, E, Koepke, J, Dikic, I, Guentert, P, Marahiel, M.A, Doetsch, V. | Deposit date: | 2013-09-17 | Release date: | 2014-04-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification. Chem.Biol., 21, 2014
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5H9U
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![BU of 5h9u by Molmil](/molmil-images/mine/5h9u) | |
8H77
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![BU of 8h77 by Molmil](/molmil-images/mine/8h77) | Hsp90-AhR-p23-XAP2 complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... | Authors: | Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. | Deposit date: | 2022-10-19 | Release date: | 2023-01-04 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of the cytosolic AhR complex. Structure, 31, 2023
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1M1Z
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1M6V
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![BU of 1m6v by Molmil](/molmil-images/mine/1m6v) | Crystal Structure of the G359F (small subunit) Point Mutant of Carbamoyl Phosphate Synthetase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, L-ornithine, ... | Authors: | Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M. | Deposit date: | 2002-07-17 | Release date: | 2002-07-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Carbamoyl-phosphate synthetase. Creation of an escape route for ammonia J.Biol.Chem., 277, 2002
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2H06
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![BU of 2h06 by Molmil](/molmil-images/mine/2h06) | |
2H07
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![BU of 2h07 by Molmil](/molmil-images/mine/2h07) | |
2H08
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![BU of 2h08 by Molmil](/molmil-images/mine/2h08) | |
8W41
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![BU of 8w41 by Molmil](/molmil-images/mine/8w41) | Cryo-EM structure of Myosin VI in the autoinhibited state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calmodulin-1, ... | Authors: | Niu, F, Wei, Z. | Deposit date: | 2023-08-23 | Release date: | 2024-02-21 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Autoinhibition and activation of myosin VI revealed by its cryo-EM structure. Nat Commun, 15, 2024
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6P9V
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![BU of 6p9v by Molmil](/molmil-images/mine/6p9v) | Crystal Structure of hMAT Mutant K289L | Descriptor: | ADENOSINE, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Miller, M.D, Xu, W, Huber, T.D, Clinger, J.A, Liu, Y, Thorson, J.S, Phillips Jr, G.N. | Deposit date: | 2019-06-10 | Release date: | 2020-04-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.051 Å) | Cite: | Methionine Adenosyltransferase Engineering to Enable Bioorthogonal Platforms for AdoMet-Utilizing Enzymes. Acs Chem.Biol., 15, 2020
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1W78
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![BU of 1w78 by Molmil](/molmil-images/mine/1w78) | E.coli FolC in complex with DHPP and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, FOLC BIFUNCTIONAL PROTEIN, MAGNESIUM ION, ... | Authors: | Mathieu, M, Debousker, G, Vincent, S, Viviani, F, Bamas-Jacques, N, Mikol, V. | Deposit date: | 2004-08-31 | Release date: | 2005-02-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Escherichia Coli Folc Structure Reveals an Unexpected Dihydrofolate Binding Site Providing an Attractive Target for Anti-Microbial Therapy J.Biol.Chem., 280, 2005
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1W7K
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![BU of 1w7k by Molmil](/molmil-images/mine/1w7k) | E.coli FolC in complex with ADP, without folate substrate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, FOLC BIFUNCTIONAL PROTEIN, MAGNESIUM ION, ... | Authors: | Mathieu, M, Debousker, G, Vincent, S, Viviani, F, Bamas-Jacques, N, Mikol, V. | Deposit date: | 2004-09-06 | Release date: | 2005-02-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Escherichia Coli Folc Structure Reveals an Unexpected Dihydrofolate Binding Site Providing an Attractive Target for Anti-Microbial Therapy J.Biol.Chem., 280, 2005
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8PTK
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![BU of 8ptk by Molmil](/molmil-images/mine/8ptk) | Composite structure of Dynein-Dynactin-JIP3-LIS1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ... | Authors: | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | Deposit date: | 2023-07-14 | Release date: | 2024-03-27 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Molecular mechanism of dynein-dynactin complex assembly by LIS1. Science, 383, 2024
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8HVR
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![BU of 8hvr by Molmil](/molmil-images/mine/8hvr) | |
2UW9
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![BU of 2uw9 by Molmil](/molmil-images/mine/2uw9) | STRUCTURE OF PKB-BETA (AKT2) COMPLEXED WITH 4-(4-chloro-phenyl)-4-(4-(1H-pyrazol-4-yl)-phenyl)-piperidine | Descriptor: | 4-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINE, GLYCOGEN SYNTHASE KINASE-3 BETA, RAC-BETA SERINE/THREONINE-PROTEIN KINASE | Authors: | Davies, T.G, Saxty, G, Woodhead, S.J, Berdini, V, Verdonk, M.L, Wyatt, P.G, Boyle, R.G, Barford, D, Downham, R, Garrett, M.D, Carr, R.A. | Deposit date: | 2007-03-19 | Release date: | 2007-05-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Identification of Inhibitors of Protein Kinase B Using Fragment-Based Lead Discovery. J.Med.Chem., 50, 2007
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1T4A
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![BU of 1t4a by Molmil](/molmil-images/mine/1t4a) | Structure of B. Subtilis PurS C2 Crystal Form | Descriptor: | PurS | Authors: | Anand, R, Hoskins, A.A, Bennett, E.M, Sintchak, M.D, Stubbe, J, Ealick, S.E. | Deposit date: | 2004-04-28 | Release date: | 2004-09-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A model for the Bacillus subtilis formylglycinamide ribonucleotide amidotransferase multiprotein complex. Biochemistry, 43, 2004
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1IBS
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![BU of 1ibs by Molmil](/molmil-images/mine/1ibs) | PHOSPHORIBOSYLDIPHOSPHATE SYNTHETASE IN COMPLEX WITH CADMIUM IONS | Descriptor: | CADMIUM ION, METHYL PHOSPHONIC ACID ADENOSINE ESTER, RIBOSE-PHOSPHATE PYROPHOSPHOKINASE, ... | Authors: | Eriksen, T.A, Kadziola, A, Larsen, S. | Deposit date: | 2001-03-29 | Release date: | 2002-02-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Binding of cations in Bacillus subtilis phosphoribosyldiphosphate synthetase and their role in catalysis. Protein Sci., 11, 2002
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